Identity
HGNC
LOCATION
11p15.3
LOCUSID
ALIAS
CH-ILKBP,MXRA2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 55742
MIM: 608120
HGNC: 14652
Ensembl: ENSG00000197702
Variants:
dbSNP: 55742
ClinVar: 55742
TCGA: ENSG00000197702
COSMIC: PARVA
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000197702 | ENST00000334956 | Q9NVD7 |
| ENSG00000197702 | ENST00000528916 | E9PS97 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33587032 | 2021 | Complex structures of Rsu1 and PINCH1 reveal a regulatory mechanism of the ILK/PINCH/Parvin complex for F-actin dynamics. | 5 |
| 33587032 | 2021 | Complex structures of Rsu1 and PINCH1 reveal a regulatory mechanism of the ILK/PINCH/Parvin complex for F-actin dynamics. | 5 |
| 30804457 | 2019 | α-Parvin promotes breast cancer progression and metastasis through interaction with G3BP2 and regulation of TWIST1 signaling. | 4 |
| 30804457 | 2019 | α-Parvin promotes breast cancer progression and metastasis through interaction with G3BP2 and regulation of TWIST1 signaling. | 4 |
| 29386624 | 2018 | A-to-I miR-378a-3p editing can prevent melanoma progression via regulation of PARVA expression. | 39 |
| 29386624 | 2018 | A-to-I miR-378a-3p editing can prevent melanoma progression via regulation of PARVA expression. | 39 |
| 25738875 | 2015 | PARVA promotes metastasis by modulating ILK signalling pathway in lung adenocarcinoma. | 14 |
| 25925587 | 2015 | Endothelial alpha-parvin controls integrity of developing vasculature and is required for maintenance of cell-cell junctions. | 24 |
| 26115385 | 2015 | Focal Adhesion Proteins α- and β-Parvin are Overexpressed in Human Colorectal Cancer and Correlate with Tumor Progression. | 7 |
| 25738875 | 2015 | PARVA promotes metastasis by modulating ILK signalling pathway in lung adenocarcinoma. | 14 |
| 25925587 | 2015 | Endothelial alpha-parvin controls integrity of developing vasculature and is required for maintenance of cell-cell junctions. | 24 |
| 26115385 | 2015 | Focal Adhesion Proteins α- and β-Parvin are Overexpressed in Human Colorectal Cancer and Correlate with Tumor Progression. | 7 |
| 24496929 | 2014 | α-Parvin, a pseudopodial constituent, promotes cell motility and is associated with lymph node metastasis of lobular breast carcinoma. | 8 |
| 24496929 | 2014 | α-Parvin, a pseudopodial constituent, promotes cell motility and is associated with lymph node metastasis of lobular breast carcinoma. | 8 |
| 23099104 | 2013 | Migfilin, α-parvin and β-parvin are differentially expressed in ovarian serous carcinoma effusions, primary tumors and solid metastases. | 2 |
Citation
Dessen P
PARVA (parvin alpha)
Atlas Genet Cytogenet Oncol Haematol. 2013-04-01
Online version: http://atlasgeneticsoncology.org/gene/53248/parva
