| Nomenclature |
|---|
| HGNC (Hugo) | PAX7 8621 |
| Cards |
|---|
| Entrez_Gene (NCBI) | PAX7 5081 paired box 7 |
| Aliases | HUP1; PAX7B; RMS2 |
| GeneCards (Weizmann) | PAX7 |
| Ensembl hg19 (Hinxton) | ENSG00000009709 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000009709 [Gene_View] ENSG00000009709 [Sequence] chr1:18631006-18736138 [Contig_View] PAX7 [Vega] |
| ICGC DataPortal | ENSG00000009709 |
| TCGA cBioPortal | PAX7 |
| AceView (NCBI) | PAX7 |
| Genatlas (Paris) | PAX7 |
| WikiGenes | 5081 |
| SOURCE (Princeton) | PAX7 |
| Genetics Home Reference (NIH) | PAX7 |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | PAX7 - chr1:18631006-18736138 + 1p36.13 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | PAX7 - 1p36.13 [Description] (hg19-Feb_2009) |
| Ensembl | PAX7 - 1p36.13 [CytoView hg19] PAX7 - 1p36.13 [CytoView hg38] |
| Mapping of homologs : NCBI | PAX7 [Mapview hg19] PAX7 [Mapview hg38] |
| OMIM | 167410 268220 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AK094779 AY578141 BC121165 BC121166 DB474828 |
| RefSeq transcript (Entrez) | NM_001135254 NM_002584 NM_013945 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | PAX7 |
| Cluster EST : Unigene | Hs.113253 [ NCBI ] |
| CGAP (NCI) | Hs.113253 |
| Alternative Splicing Gallery | ENSG00000009709 |
| Gene Expression | PAX7 [ NCBI-GEO ] PAX7 [ EBI - ARRAY_EXPRESS ]
PAX7 [ SEEK ] PAX7 [ MEM ] |
| Gene Expression Viewer (FireBrowse) | PAX7 [ Firebrowse - Broad ] |
| SOURCE (Princeton) | Expression in : [Datasets] [Normal Tissue Atlas] [carcinoma Classsification] [NCI60] |
| Genevestigator | Expression in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 5081 |
| GTEX Portal (Tissue expression) | PAX7 |
| Human Protein Atlas | ENSG00000009709-PAX7 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | P23759 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | P23759 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | P23759 |
| Splice isoforms : SwissVar | P23759 |
| PhosPhoSitePlus | P23759 |
| Domaine pattern : Prosite (Expaxy) | HOMEOBOX_1 (PS00027) HOMEOBOX_2 (PS50071) OAR (PS50803) PAIRED_1 (PS00034) PAIRED_2 (PS51057) |
| Domains : Interpro (EBI) | Homeobox-like_sf Homeobox_CS Homeobox_dom OAR_dom Paired_dom Pax7_C WH-like_DNA-bd_sf |
| Domain families : Pfam (Sanger) | Homeobox (PF00046) PAX (PF00292) Pax7 (PF12360) |
| Domain families : Pfam (NCBI) | pfam00046 pfam00292 pfam12360 |
| Domain families : Smart (EMBL) | HOX (SM00389) PAX (SM00351) |
| Conserved Domain (NCBI) | PAX7 |
| DMDM Disease mutations | 5081 |
| Blocks (Seattle) | PAX7 |
| Superfamily | P23759 |
| Human Protein Atlas [tissue] | ENSG00000009709-PAX7 [tissue] |
| Peptide Atlas | P23759 |
| HPRD | 01331 |
| IPI | IPI00012894 IPI00004431 IPI00719545 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | P23759 |
| IntAct (EBI) | P23759 |
| FunCoup | ENSG00000009709 |
| BioGRID | PAX7 |
| STRING (EMBL) | PAX7 |
| ZODIAC | PAX7 |
| Ontologies - Pathways |
|---|
| QuickGO | P23759 |
| Ontology : AmiGO | DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity nucleus chromatin remodeling transcription by RNA polymerase II anatomical structure morphogenesis regulation of cell fate commitment skeletal muscle satellite cell commitment RNA polymerase II general transcription initiation factor activity spinal cord association neuron differentiation dorsal/ventral neural tube patterning positive regulation of histone methylation negative regulation of apoptotic process regulation of protein binding skeletal muscle tissue regeneration sequence-specific DNA binding positive regulation of transcription by RNA polymerase II neuron fate commitment embryonic skeletal system development cartilage development muscle tissue morphogenesis positive regulation of myoblast proliferation |
| Ontology : EGO-EBI | DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity nucleus chromatin remodeling transcription by RNA polymerase II anatomical structure morphogenesis regulation of cell fate commitment skeletal muscle satellite cell commitment RNA polymerase II general transcription initiation factor activity spinal cord association neuron differentiation dorsal/ventral neural tube patterning positive regulation of histone methylation negative regulation of apoptotic process regulation of protein binding skeletal muscle tissue regeneration sequence-specific DNA binding positive regulation of transcription by RNA polymerase II neuron fate commitment embryonic skeletal system development cartilage development muscle tissue morphogenesis positive regulation of myoblast proliferation |
| Pathways : KEGG | Transcriptional misregulation in cancer |
| NDEx Network | PAX7 |
| Atlas of Cancer Signalling Network | PAX7 |
| Wikipedia pathways | PAX7 |
| Orthology - Evolution |
|---|
| OrthoDB | 5081 |
| GeneTree (enSembl) | ENSG00000009709 |
| Phylogenetic Trees/Animal Genes : TreeFam | PAX7 |
| HOGENOM | P23759 |
| Homologs : HomoloGene | PAX7 |
| Homology/Alignments : Family Browser (UCSC) | PAX7 |
| Gene fusions - Rearrangements |
|---|
| Fusion : Mitelman | PAX7/FOXO1 [1p36.13/13q14.11] |
| Fusion : Mitelman | UBR4/PAX7 [1p36.13/1p36.13] [t(1;1)(p36;p36)] |
| Fusion Portal | UBR4 1p36.13 PAX7 1p36.13 LGG |
| Fusion : Quiver | PAX7 |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | PAX7 [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | PAX7 |
| dbVar | PAX7 |
| ClinVar | PAX7 |
| 1000_Genomes | PAX7 |
| Exome Variant Server | PAX7 |
| ExAC (Exome Aggregation Consortium) | ENSG00000009709 |
| GNOMAD Browser | ENSG00000009709 |
| Varsome Browser | PAX7 |
| Genetic variants : HAPMAP | 5081 |
| Genomic Variants (DGV) | PAX7 [DGVbeta] |
| DECIPHER | PAX7 [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | PAX7 |
| Mutations |
|---|
| ICGC Data Portal | PAX7 |
| TCGA Data Portal | PAX7 |
| Broad Tumor Portal | PAX7 |
| OASIS Portal | PAX7 [ Somatic mutations - Copy number] |
| Cancer Gene: Census | PAX7 |
| Somatic Mutations in Cancer : COSMIC | PAX7 [overview] [genome browser] [tissue] [distribution] |
| Mutations and Diseases : HGMD | PAX7 |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| BioMuta | search PAX7 |
| DgiDB (Drug Gene Interaction Database) | PAX7 |
| DoCM (Curated mutations) | PAX7 (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | PAX7 (select a term) |
| intoGen | PAX7 |
| Cancer3D | PAX7(select the gene name) |
| Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 167410 268220 |
| Orphanet | 14329 |
| DisGeNET | PAX7 |
| Medgen | PAX7 |
| Genetic Testing Registry | PAX7
|
| NextProt | P23759 [Medical] |
| TSGene | 5081 |
| GENETests | PAX7 |
| Target Validation | PAX7 |
| Huge Navigator |
PAX7 [HugePedia] |
| snp3D : Map Gene to Disease | 5081 |
| BioCentury BCIQ | PAX7 |
| ClinGen | PAX7 |
| Clinical trials, drugs, therapy |
|---|
| Chemical/Protein Interactions : CTD | 5081 |
| Chemical/Pharm GKB Gene | PA32961 |
| Clinical trial | PAX7 |
| Miscellaneous |
|---|
| canSAR (ICR) | PAX7 (select the gene name) |
| DataMed Index | PAX7 |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 65 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| CoreMine | PAX7 |
| EVEX | PAX7 |
| GoPubMed | PAX7 |
| iHOP | PAX7 |
