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PAXX (PAXX, non-homologous end joining factor)

Identity

Other aliasC9orf142
XLS
HGNC (Hugo) PAXX
LocusID (NCBI) 286257
Atlas_Id 57040
Location 9q34.3  [Link to chromosome band 9q34]
Location_base_pair Starts at 136992418 and ends at 136993988 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute


External links

Nomenclature
HGNC (Hugo)PAXX   27849
Cards
Entrez_Gene (NCBI)PAXX  286257  PAXX, non-homologous end joining factor
AliasesC9orf142; XLS
GeneCards (Weizmann)PAXX
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr9:136992418-136993988 [Contig_View]  PAXX [Vega]
TCGA cBioPortalPAXX
AceView (NCBI)PAXX
Genatlas (Paris)PAXX
WikiGenes286257
SOURCE (Princeton)PAXX
Genetics Home Reference (NIH)PAXX
Genomic and cartography
GoldenPath hg38 (UCSC)PAXX  -     chr9:136992418-136993988 +  9q34.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PAXX  -     9q34.3   [Description]    (hg19-Feb_2009)
EnsemblPAXX - 9q34.3 [CytoView hg19]  PAXX - 9q34.3 [CytoView hg38]
Mapping of homologs : NCBIPAXX [Mapview hg19]  PAXX [Mapview hg38]
OMIM616315   
Gene and transcription
Genbank (Entrez)AA404597 BC002613 BC038191 HQ447605
RefSeq transcript (Entrez)NM_001329678 NM_183241
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PAXX
Cluster EST : UnigeneHs.409582 [ NCBI ]
CGAP (NCI)Hs.409582
Gene ExpressionPAXX [ NCBI-GEO ]   PAXX [ EBI - ARRAY_EXPRESS ]   PAXX [ SEEK ]   PAXX [ MEM ]
Gene Expression Viewer (FireBrowse)PAXX [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)286257
GTEX Portal (Tissue expression)PAXX
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BUH6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BUH6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BUH6
Splice isoforms : SwissVarQ9BUH6
PhosPhoSitePlusQ9BUH6
Domains : Interpro (EBI)PAXX   
Domain families : Pfam (Sanger)PAXX (PF15384)   
Domain families : Pfam (NCBI)pfam15384   
Conserved Domain (NCBI)PAXX
DMDM Disease mutations286257
Blocks (Seattle)PAXX
PDB (SRS)3WTD    3WTF    4WJA   
PDB (PDBSum)3WTD    3WTF    4WJA   
PDB (IMB)3WTD    3WTF    4WJA   
PDB (RSDB)3WTD    3WTF    4WJA   
Structural Biology KnowledgeBase3WTD    3WTF    4WJA   
SCOP (Structural Classification of Proteins)3WTD    3WTF    4WJA   
CATH (Classification of proteins structures)3WTD    3WTF    4WJA   
SuperfamilyQ9BUH6
Peptide AtlasQ9BUH6
IPIIPI00030968   IPI00845499   
Protein Interaction databases
DIP (DOE-UCLA)Q9BUH6
IntAct (EBI)Q9BUH6
BioGRIDPAXX
STRING (EMBL)PAXX
ZODIACPAXX
Ontologies - Pathways
QuickGOQ9BUH6
Ontology : AmiGOprotein binding  nucleus  double-strand break repair via nonhomologous end joining  cellular response to DNA damage stimulus  protein complex scaffold activity  site of double-strand break  protein homodimerization activity  Ku70:Ku80 complex  DNA ligation involved in DNA repair  extracellular exosome  nonhomologous end joining complex  
Ontology : EGO-EBIprotein binding  nucleus  double-strand break repair via nonhomologous end joining  cellular response to DNA damage stimulus  protein complex scaffold activity  site of double-strand break  protein homodimerization activity  Ku70:Ku80 complex  DNA ligation involved in DNA repair  extracellular exosome  nonhomologous end joining complex  
NDEx NetworkPAXX
Atlas of Cancer Signalling NetworkPAXX
Wikipedia pathwaysPAXX
Orthology - Evolution
OrthoDB286257
Phylogenetic Trees/Animal Genes : TreeFamPAXX
HOVERGENQ9BUH6
HOGENOMQ9BUH6
Homologs : HomoloGenePAXX
Homology/Alignments : Family Browser (UCSC)PAXX
Gene fusions - Rearrangements
Tumor Fusion PortalPAXX
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPAXX [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PAXX
dbVarPAXX
ClinVarPAXX
1000_GenomesPAXX 
Exome Variant ServerPAXX
ExAC (Exome Aggregation Consortium)
Genetic variants : HAPMAP286257
Genomic Variants (DGV)PAXX [DGVbeta]
DECIPHERPAXX [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPAXX 
Mutations
ICGC Data PortalPAXX 
TCGA Data PortalPAXX 
Broad Tumor PortalPAXX
OASIS PortalPAXX [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDPAXX
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PAXX
DgiDB (Drug Gene Interaction Database)PAXX
DoCM (Curated mutations)PAXX (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PAXX (select a term)
intoGenPAXX
Cancer3DPAXX(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616315   
Orphanet
DisGeNETPAXX
MedgenPAXX
Genetic Testing Registry PAXX
NextProtQ9BUH6 [Medical]
TSGene286257
GENETestsPAXX
Target ValidationPAXX
Huge Navigator PAXX [HugePedia]
snp3D : Map Gene to Disease286257
BioCentury BCIQPAXX
ClinGenPAXX
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD286257
Chemical/Pharm GKB GenePA143485344
Clinical trialPAXX
Miscellaneous
canSAR (ICR)PAXX (select the gene name)
Probes
Litterature
PubMed11 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePAXX
EVEXPAXX
GoPubMedPAXX
iHOPPAXX
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:27:53 CET 2017

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