Atlas of Genetics and Cytogenetics in Oncology and Haematology

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   
X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

PBK (PDZ binding kinase)

Identity

Other namesCT84
Nori-3
SPK
TOPK
HGNC (Hugo) PBK
LocusID (NCBI) 55872
Location 8p21.1
Location_base_pair Starts at 27667138 and ends at 27695349 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)PBK   18282
Entrez_Gene (NCBI)PBK  55872  PDZ binding kinase
Cards
GeneCards (Weizmann)PBK
Ensembl (Hinxton)ENSG00000168078 [Gene_View]  chr8:27667138-27695349 [Contig_View]  PBK [Vega]
AceView (NCBI)PBK
Genatlas (Paris)PBK
SOURCE (Stanford)NM_018492
Genomic and cartography
GoldenPath (UCSC)PBK  -  8p21.1   chr8:27667138-27695349 -  8p21.1   [Description]    (hg19-Feb_2009)
EnsemblPBK - 8p21.1 [CytoView]
Mapping of homologs : NCBIPBK [Mapview]
OMIM611210   
Gene and transcription
Genbank (Entrez)AB027249 AB027250 AF189722 AF237709 AK027291
RefSeq transcript (SRS)NM_018492
RefSeq transcript (Entrez)NM_018492
RefSeq genomic (SRS)AC_000140 NC_000008 NC_018919 NT_167187 NW_001839127 NW_004078035
RefSeq genomic (Entrez)AC_000140 NC_000008 NC_018919 NT_167187 NW_001839127 NW_004078035
Consensus coding sequences : CCDS (NCBI)PBK
Cluster EST : UnigeneHs.104741 [ SRS ] Hs.104741 [ NCBI ]
CGAP (NCI)Hs.104741
Alternative Splicing : Fast-db (Paris)GSHG0029491
Alternative Splicing GalleryENSG00000168078
Gene ExpressionPBK [ NCBI-GEO ]   PBK [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96KB5 (SRS) Q96KB5 (Uniprot)
NextProtQ96KB5
With graphics : InterProQ96KB5
Splice isoforms : SwissVarQ96KB5(Swissvar)
Domaine pattern : Prosite (SRS)PROTEIN_KINASE_ATP (PS00107)    PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_ST (PS00108)   
Domaine pattern : Prosite (Expaxy)PROTEIN_KINASE_ATP (PS00107)    PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_ST (PS00108)   
Domains : Interpro (SRS)Kinase-like_dom    Prot_kinase_cat_dom    Ser/Thr_kinase_AS   
Domains : Interpro (EBI)Kinase-like_dom    Prot_kinase_cat_dom    Ser/Thr_kinase_AS   
Related proteins : CluSTrQ96KB5
Domain families : Pfam (SRS)Pkinase (PF00069)   
Domain families : Pfam (Sanger)Pkinase (PF00069)   
Domain families : Pfam (NCBI)pfam00069   
DMDM55872
Blocks (Seattle)Q96KB5
Human Protein AtlasENSG00000168078
HPRD17822
IPIIPI00306708   IPI00980645   IPI00974208   IPI00974235   
Protein Interaction databases
DIP (DOE-UCLA)Q96KB5
IntAct (EBI)Q96KB5
FunCoupENSG00000168078
REACTOMEPBK
Protein Interaction Database55872
BioGRIDPBK
InParanoidQ96KB5
Interologous Interaction database Q96KB5
IntegromeDBPBK
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)PBK
SNP (GeneSNP Utah)PBK
SNP : HGBasePBK
Genetic variants : HAPMAPPBK
Somatic Mutations in Cancer : COSMICPBK 
CONAN: Copy Number AnalysisPBK 
Mutations and Diseases : HGMDPBK
OMIM611210   
GENETests611210   
Disease Genetic AssociationPBK
Huge Navigator PBK [HugePedia]  PBK [HugeCancerGEM]
Genomic VariantsPBK  PBK [DGVbeta]
ClinVarPBK
snp3D : Map Gene to Disease55872
General knowledge
Homologs : HomoloGenePBK
Homology/Alignments : Family Browser (UCSC)PBK
Phylogenetic Trees/Animal Genes : TreeFamPBK
Catalytic activity : Enzyme2.7.12.2 [ Enzyme-Expasy ]   2.7.12.2 [ Enzyme-SRS ]   2.7.12.2 [ IntEnz-EBI ]   2.7.12.2 [ BRENDA ]   2.7.12.2 [ KEGG ]   
Chemical/Protein Interactions : CTD55872
Chemical/Pharm GKB GenePA134925802
Clinical trialPBK
Cancer Resource (Charite)ENSG00000168078
Ontology : AmiGOprotein serine/threonine kinase activity  protein binding  ATP binding  cellular_component  protein phosphorylation  mitosis  
Ontology : EGO-EBIprotein serine/threonine kinase activity  protein binding  ATP binding  cellular_component  protein phosphorylation  mitosis  
Other databases
Probes
Litterature
PubMed41 Pubmed reference(s) in Entrez
PubGenePBK
iHOPPBK
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jun 14 17:36:03 CEST 2013
Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.