Atlas of Genetics and Cytogenetics in Oncology and Haematology

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PBRM1 (polybromo 1)

Identity

Other namesBAF180
PB1
HGNC (Hugo) PBRM1
LocusID (NCBI) 55193
Location 3p21.1
Location_base_pair Starts at 52579368 and ends at 52719866 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)PBRM1   30064
Entrez_Gene (NCBI)PBRM1  55193  polybromo 1
Cards
GeneCards (Weizmann)PBRM1
Ensembl (Hinxton)ENSG00000163939 [Gene_View]  chr3:52579368-52719866 [Contig_View]  PBRM1 [Vega]
AceView (NCBI)PBRM1
Genatlas (Paris)PBRM1
SOURCE (Stanford)NM_018165 NM_018313 NM_181041 NM_181042
Genomic and cartography
GoldenPath (UCSC)PBRM1  -  3p21.1   chr3:52579368-52719866 -  3p21.1   [Description]    (hg19-Feb_2009)
EnsemblPBRM1 - 3p21.1 [CytoView]
Mapping of homologs : NCBIPBRM1 [Mapview]
OMIM606083   
Gene and transcription
Genbank (Entrez)AA047886 AF177387 AF197569 AF225870 AF225871
RefSeq transcript (SRS)NM_018165 NM_018313 NM_181041 NM_181042
RefSeq transcript (Entrez)NM_018165 NM_018313 NM_181041 NM_181042
RefSeq genomic (SRS)AC_000135 NC_000003 NC_018914 NG_032108 NT_022517 NW_001838877 NW_004078011
RefSeq genomic (Entrez)AC_000135 NC_000003 NC_018914 NG_032108 NT_022517 NW_001838877 NW_004078011
Consensus coding sequences : CCDS (NCBI)PBRM1
Cluster EST : UnigeneHs.476320 [ SRS ] Hs.476320 [ NCBI ]
CGAP (NCI)Hs.476320
Alternative Splicing : Fast-db (Paris)GSHG0021765
Alternative Splicing GalleryENSG00000163939
Gene ExpressionPBRM1 [ NCBI-GEO ]   PBRM1 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86U86 (SRS) Q86U86 (Uniprot)
NextProtQ86U86
With graphics : InterProQ86U86
Splice isoforms : SwissVarQ86U86(Swissvar)
Domaine pattern : Prosite (SRS)BAH (PS51038)    BROMODOMAIN_1 (PS00633)    BROMODOMAIN_2 (PS50014)    HMG_BOX_2 (PS50118)   
Domaine pattern : Prosite (Expaxy)BAH (PS51038)    BROMODOMAIN_1 (PS00633)    BROMODOMAIN_2 (PS50014)    HMG_BOX_2 (PS50118)   
Domains : Interpro (SRS)BAH_dom    Bromodomain    Bromodomain_CS    HMG_superfamily   
Domains : Interpro (EBI)BAH_dom    Bromodomain    Bromodomain_CS    HMG_superfamily   
Related proteins : CluSTrQ86U86
Domain families : Pfam (SRS)BAH (PF01426)    Bromodomain (PF00439)    HMG_box (PF00505)   
Domain families : Pfam (Sanger)BAH (PF01426)    Bromodomain (PF00439)    HMG_box (PF00505)   
Domain families : Pfam (NCBI)pfam01426    pfam00439    pfam00505   
Domain families : Smart (EMBL)BAH (SM00439)  BROMO (SM00297)  HMG (SM00398)  
DMDM55193
Blocks (Seattle)Q86U86
PDB (SRS)2KTB    3G0J    3HMF    3IU5    3IU6    3K2J    3LJW    3MB4    3TLP   
PDB (PDBSum)2KTB    3G0J    3HMF    3IU5    3IU6    3K2J    3LJW    3MB4    3TLP   
PDB (IMB)2KTB    3G0J    3HMF    3IU5    3IU6    3K2J    3LJW    3MB4    3TLP   
PDB (RSDB)2KTB    3G0J    3HMF    3IU5    3IU6    3K2J    3LJW    3MB4    3TLP   
Human Protein AtlasENSG00000163939
IPIIPI00384176   IPI00301041   IPI00334894   IPI00640304   IPI00023097   IPI00398781   IPI00873041   IPI00910435   IPI00909142   IPI00451426   IPI00001787   IPI00917738   IPI00917187   IPI00917316   IPI00916357   IPI00917875   IPI00918010   IPI00917348   IPI00916875   
Protein Interaction databases
DIP (DOE-UCLA)Q86U86
IntAct (EBI)Q86U86
FunCoupENSG00000163939
REACTOMEPBRM1
Protein Interaction Database55193
BioGRIDPBRM1
InParanoidQ86U86
Interologous Interaction database Q86U86
IntegromeDBPBRM1
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)PBRM1
SNP (GeneSNP Utah)PBRM1
SNP : HGBasePBRM1
Genetic variants : HAPMAPPBRM1
Cancer Gene: CensusPBRM1 
Somatic Mutations in Cancer : COSMICPBRM1 
CONAN: Copy Number AnalysisPBRM1 
Mutations and Diseases : HGMDPBRM1
OMIM606083   
GENETests606083   
Disease Genetic AssociationPBRM1
Huge Navigator PBRM1 [HugePedia]  PBRM1 [HugeCancerGEM]
Genomic VariantsPBRM1  PBRM1 [DGVbeta]
snp3D : Map Gene to Disease55193
General knowledge
Homologs : HomoloGenePBRM1
Homology/Alignments : Family Browser (UCSC)PBRM1
Phylogenetic Trees/Animal Genes : TreeFamPBRM1
Chemical/Protein Interactions : CTD55193
Chemical/Pharm GKB GenePA162398846
Clinical trialPBRM1
Cancer Resource (Charite)ENSG00000163939
Ontology : AmiGOnuclear chromosome  kinetochore  placenta development  DNA binding  chromatin binding  protein binding  chromatin remodeling  transcription, DNA-dependent  regulation of transcription, DNA-dependent  mitosis  heart development  negative regulation of cell proliferation  
Ontology : EGO-EBInuclear chromosome  kinetochore  placenta development  DNA binding  chromatin binding  protein binding  chromatin remodeling  transcription, DNA-dependent  regulation of transcription, DNA-dependent  mitosis  heart development  negative regulation of cell proliferation  
Other databases
Probes
Litterature
PubMed50 Pubmed reference(s) in Entrez
PubGenePBRM1
iHOPPBRM1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:35:40 CEST 2013
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