Atlas of Genetics and Cytogenetics in Oncology and Haematology


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PBX2 (pre-B-cell leukemia homeobox 2)

Identity

Other namesG17
HOX12
PBX2MHC
HGNC (Hugo) PBX2
LocusID (NCBI) 5089
Location 6p21.32
Location_base_pair Starts at 32152510 and ends at 32157963 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)PBX2   8633
Cards
Entrez_Gene (NCBI)PBX2  5089  pre-B-cell leukemia homeobox 2
GeneCards (Weizmann)PBX2
Ensembl (Hinxton)ENSG00000204304 [Gene_View]  chr6:32152510-32157963 [Contig_View]  PBX2 [Vega]
ICGC DataPortalENSG00000204304
cBioPortalPBX2
AceView (NCBI)PBX2
Genatlas (Paris)PBX2
WikiGenes5089
SOURCE (Princeton)NM_002586
Genomic and cartography
GoldenPath (UCSC)PBX2  -  6p21.32   chr6:32152510-32157963 -  6p21.32   [Description]    (hg19-Feb_2009)
EnsemblPBX2 - 6p21.32 [CytoView]
Mapping of homologs : NCBIPBX2 [Mapview]
OMIM176311   
Gene and transcription
Genbank (Entrez)BC003111 BC082261 BQ182713 BT009823 DB162975
RefSeq transcript (Entrez)NM_002586
RefSeq genomic (Entrez)AC_000138 NC_000006 NC_018917 NT_007592 NT_113891 NT_167244 NT_167246 NT_167247 NT_167248 NT_167249 NW_001838980 NW_004929326
Consensus coding sequences : CCDS (NCBI)PBX2
Cluster EST : UnigeneHs.718462 [ NCBI ]
CGAP (NCI)Hs.718462
Alternative Splicing : Fast-db (Paris)GSHG0026493
Alternative Splicing GalleryENSG00000204304
Gene ExpressionPBX2 [ NCBI-GEO ]     PBX2 [ SEEK ]   PBX2 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP40425 (Uniprot)
NextProtP40425  [Medical]
With graphics : InterProP40425
Splice isoforms : SwissVarP40425 (Swissvar)
Domaine pattern : Prosite (Expaxy)HOMEOBOX_1 (PS00027)    HOMEOBOX_2 (PS50071)   
Domains : Interpro (EBI)Homeobox_CS [organisation]   Homeobox_dom [organisation]   Homeodomain-like [organisation]   PBX [organisation]  
Related proteins : CluSTrP40425
Domain families : Pfam (Sanger)Homeobox (PF00046)    PBC (PF03792)   
Domain families : Pfam (NCBI)pfam00046    pfam03792   
Domain families : Smart (EMBL)HOX (SM00389)  
DMDM Disease mutations5089
Blocks (Seattle)P40425
Human Protein AtlasENSG00000204304 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasP40425
HPRD08890
IPIIPI00028416   IPI01021527   IPI01022892   IPI01022588   
Protein Interaction databases
DIP (DOE-UCLA)P40425
IntAct (EBI)P40425
FunCoupENSG00000204304
BioGRIDPBX2
InParanoidP40425
Interologous Interaction database P40425
IntegromeDBPBX2
STRING (EMBL)PBX2
Ontologies - Pathways
Ontology : AmiGOchromatin binding  sequence-specific DNA binding transcription factor activity  nucleus  transcription factor complex  transcription, DNA-templated  transcription factor binding  proximal/distal pattern formation  embryonic limb morphogenesis  sequence-specific DNA binding  positive regulation of transcription from RNA polymerase II promoter  
Ontology : EGO-EBIchromatin binding  sequence-specific DNA binding transcription factor activity  nucleus  transcription factor complex  transcription, DNA-templated  transcription factor binding  proximal/distal pattern formation  embryonic limb morphogenesis  sequence-specific DNA binding  positive regulation of transcription from RNA polymerase II promoter  
Protein Interaction DatabasePBX2
Wikipedia pathwaysPBX2
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)PBX2
snp3D : Map Gene to Disease5089
SNP (GeneSNP Utah)PBX2
SNP : HGBasePBX2
Genetic variants : HAPMAPPBX2
Exome VariantPBX2
1000_GenomesPBX2 
ICGC programENSG00000204304 
Somatic Mutations in Cancer : COSMICPBX2 
CONAN: Copy Number AnalysisPBX2 
Mutations and Diseases : HGMDPBX2
Mutations and Diseases : intOGenPBX2
Genomic VariantsPBX2  PBX2 [DGVbeta]
dbVarPBX2
ClinVarPBX2
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM176311   
MedgenPBX2
GENETestsPBX2
Disease Genetic AssociationPBX2
Huge Navigator PBX2 [HugePedia]  PBX2 [HugeCancerGEM]
General knowledge
Homologs : HomoloGenePBX2
Homology/Alignments : Family Browser (UCSC)PBX2
Phylogenetic Trees/Animal Genes : TreeFamPBX2
Chemical/Protein Interactions : CTD5089
Chemical/Pharm GKB GenePA32971
Clinical trialPBX2
Cancer Resource (Charite)ENSG00000204304
Other databases
Probes
Litterature
PubMed35 Pubmed reference(s) in Entrez
CoreMinePBX2
iHOPPBX2
OncoSearchPBX2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 26 16:58:59 CEST 2014

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