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PBXIP1 (PBX homeobox interacting protein 1)

Identity

Alias_namespre-B-cell leukemia transcription factor interacting protein 1
pre-B-cell leukemia homeobox interacting protein 1
Alias_symbol (synonym)HPIP
Other alias
HGNC (Hugo) PBXIP1
LocusID (NCBI) 57326
Atlas_Id 41650
Location 1q21.3  [Link to chromosome band 1q21]
Location_base_pair Starts at 154944083 and ends at 154956163 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
PBXIP1 (1q21.3) / FAIM2 (12q13.12)PBXIP1 (1q21.3) / MAN2B2 (4p16.1)PBXIP1 (1q21.3) / PMVK (1q21.3)
VGLL3 (3p12.1) / PBXIP1 (1q21.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]

Solid Tumors TT_t0101q21q21ID103876


External links

Nomenclature
HGNC (Hugo)PBXIP1   21199
Cards
Entrez_Gene (NCBI)PBXIP1  57326  PBX homeobox interacting protein 1
AliasesHPIP
GeneCards (Weizmann)PBXIP1
Ensembl hg19 (Hinxton)ENSG00000163346 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000163346 [Gene_View]  ENSG00000163346 [Sequence]  chr1:154944083-154956163 [Contig_View]  PBXIP1 [Vega]
ICGC DataPortalENSG00000163346
TCGA cBioPortalPBXIP1
AceView (NCBI)PBXIP1
Genatlas (Paris)PBXIP1
WikiGenes57326
SOURCE (Princeton)PBXIP1
Genetics Home Reference (NIH)PBXIP1
Genomic and cartography
GoldenPath hg38 (UCSC)PBXIP1  -     chr1:154944083-154956163 -  1q21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PBXIP1  -     1q21.3   [Description]    (hg19-Feb_2009)
GoldenPathPBXIP1 - 1q21.3 [CytoView hg19]  PBXIP1 - 1q21.3 [CytoView hg38]
ImmunoBaseENSG00000163346
Mapping of homologs : NCBIPBXIP1 [Mapview hg19]  PBXIP1 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF221521 AK022497 AK023219 AK300544 AK300987
RefSeq transcript (Entrez)NM_001317734 NM_001317735 NM_020524
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PBXIP1
Cluster EST : UnigeneHs.505806 [ NCBI ]
CGAP (NCI)Hs.505806
Alternative Splicing GalleryENSG00000163346
Gene ExpressionPBXIP1 [ NCBI-GEO ]   PBXIP1 [ EBI - ARRAY_EXPRESS ]   PBXIP1 [ SEEK ]   PBXIP1 [ MEM ]
Gene Expression Viewer (FireBrowse)PBXIP1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57326
GTEX Portal (Tissue expression)PBXIP1
Human Protein AtlasENSG00000163346-PBXIP1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96AQ6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96AQ6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96AQ6
Splice isoforms : SwissVarQ96AQ6
PhosPhoSitePlusQ96AQ6
Domains : Interpro (EBI)PBXIP1   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)PBXIP1
DMDM Disease mutations57326
Blocks (Seattle)PBXIP1
SuperfamilyQ96AQ6
Human Protein Atlas [tissue]ENSG00000163346-PBXIP1 [tissue]
Peptide AtlasQ96AQ6
HPRD17823
IPIIPI00332106   IPI00645060   IPI00220556   IPI00828109   IPI01021919   IPI01013708   IPI01011313   IPI00514346   IPI00980442   
Protein Interaction databases
DIP (DOE-UCLA)Q96AQ6
IntAct (EBI)Q96AQ6
FunCoupENSG00000163346
BioGRIDPBXIP1
STRING (EMBL)PBXIP1
ZODIACPBXIP1
Ontologies - Pathways
QuickGOQ96AQ6
Ontology : AmiGOtranscription corepressor activity  protein binding  nucleus  cytosol  microtubule  multicellular organism development  cell differentiation  negative regulation of transcription, DNA-templated  
Ontology : EGO-EBItranscription corepressor activity  protein binding  nucleus  cytosol  microtubule  multicellular organism development  cell differentiation  negative regulation of transcription, DNA-templated  
NDEx NetworkPBXIP1
Atlas of Cancer Signalling NetworkPBXIP1
Wikipedia pathwaysPBXIP1
Orthology - Evolution
OrthoDB57326
GeneTree (enSembl)ENSG00000163346
Phylogenetic Trees/Animal Genes : TreeFamPBXIP1
HOGENOMQ96AQ6
Homologs : HomoloGenePBXIP1
Homology/Alignments : Family Browser (UCSC)PBXIP1
Gene fusions - Rearrangements
Fusion : MitelmanPBXIP1/PMVK [1q21.3/1q21.3]  
Fusion : QuiverPBXIP1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPBXIP1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PBXIP1
dbVarPBXIP1
ClinVarPBXIP1
1000_GenomesPBXIP1 
Exome Variant ServerPBXIP1
ExAC (Exome Aggregation Consortium)ENSG00000163346
GNOMAD BrowserENSG00000163346
Varsome BrowserPBXIP1
Genetic variants : HAPMAP57326
Genomic Variants (DGV)PBXIP1 [DGVbeta]
DECIPHERPBXIP1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPBXIP1 
Mutations
ICGC Data PortalPBXIP1 
TCGA Data PortalPBXIP1 
Broad Tumor PortalPBXIP1
OASIS PortalPBXIP1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPBXIP1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DPBXIP1
Mutations and Diseases : HGMDPBXIP1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PBXIP1
DgiDB (Drug Gene Interaction Database)PBXIP1
DoCM (Curated mutations)PBXIP1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PBXIP1 (select a term)
intoGenPBXIP1
Cancer3DPBXIP1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETPBXIP1
MedgenPBXIP1
Genetic Testing Registry PBXIP1
NextProtQ96AQ6 [Medical]
TSGene57326
GENETestsPBXIP1
Target ValidationPBXIP1
Huge Navigator PBXIP1 [HugePedia]
snp3D : Map Gene to Disease57326
BioCentury BCIQPBXIP1
ClinGenPBXIP1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57326
Chemical/Pharm GKB GenePA134956095
Clinical trialPBXIP1
Miscellaneous
canSAR (ICR)PBXIP1 (select the gene name)
DataMed IndexPBXIP1
Probes
Litterature
PubMed38 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePBXIP1
EVEXPBXIP1
GoPubMedPBXIP1
iHOPPBXIP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Aug 26 18:22:23 CEST 2019

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