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PCBP1 (poly(rC) binding protein 1)

Identity

Alias_namespoly(rC)-binding protein 1
Alias_symbol (synonym)HNRPE1
hnRNP-E1
HNRPX
hnRNP-X
Other aliasHEL-S-85
HGNC (Hugo) PCBP1
LocusID (NCBI) 5093
Atlas_Id 43728
Location 2p13.3  [Link to chromosome band 2p13]
Location_base_pair Starts at 70087453 and ends at 70089202 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
B2M (15q21.1) / PCBP1 (2p13.3)GNLY (2p11.2) / PCBP1 (2p13.3)PCBP1 (2p13.3) / B2M (15q21.1)
PCBP1 (2p13.3) / PCBP1 (2p13.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PCBP1   8647
Cards
Entrez_Gene (NCBI)PCBP1  5093  poly(rC) binding protein 1
AliasesHEL-S-85; HNRPE1; HNRPX; hnRNP-E1; 
hnRNP-X
GeneCards (Weizmann)PCBP1
Ensembl hg19 (Hinxton)ENSG00000169564 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000169564 [Gene_View]  chr2:70087453-70089202 [Contig_View]  PCBP1 [Vega]
ICGC DataPortalENSG00000169564
TCGA cBioPortalPCBP1
AceView (NCBI)PCBP1
Genatlas (Paris)PCBP1
WikiGenes5093
SOURCE (Princeton)PCBP1
Genetics Home Reference (NIH)PCBP1
Genomic and cartography
GoldenPath hg38 (UCSC)PCBP1  -     chr2:70087453-70089202 +  2p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PCBP1  -     2p13.3   [Description]    (hg19-Feb_2009)
EnsemblPCBP1 - 2p13.3 [CytoView hg19]  PCBP1 - 2p13.3 [CytoView hg38]
Mapping of homologs : NCBIPCBP1 [Mapview hg19]  PCBP1 [Mapview hg38]
OMIM601209   
Gene and transcription
Genbank (Entrez)AK130439 AK314225 BC039742 BM794597 FJ224329
RefSeq transcript (Entrez)NM_006196
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PCBP1
Cluster EST : UnigeneHs.2853 [ NCBI ]
CGAP (NCI)Hs.2853
Alternative Splicing GalleryENSG00000169564
Gene ExpressionPCBP1 [ NCBI-GEO ]   PCBP1 [ EBI - ARRAY_EXPRESS ]   PCBP1 [ SEEK ]   PCBP1 [ MEM ]
Gene Expression Viewer (FireBrowse)PCBP1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5093
GTEX Portal (Tissue expression)PCBP1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ15365   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ15365  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ15365
Splice isoforms : SwissVarQ15365
PhosPhoSitePlusQ15365
Domaine pattern : Prosite (Expaxy)KH_TYPE_1 (PS50084)   
Domains : Interpro (EBI)KH_dom    KH_dom_type_1   
Domain families : Pfam (Sanger)KH_1 (PF00013)   
Domain families : Pfam (NCBI)pfam00013   
Domain families : Smart (EMBL)KH (SM00322)  
Conserved Domain (NCBI)PCBP1
DMDM Disease mutations5093
Blocks (Seattle)PCBP1
PDB (SRS)1WVN    1ZTG    3VKE   
PDB (PDBSum)1WVN    1ZTG    3VKE   
PDB (IMB)1WVN    1ZTG    3VKE   
PDB (RSDB)1WVN    1ZTG    3VKE   
Structural Biology KnowledgeBase1WVN    1ZTG    3VKE   
SCOP (Structural Classification of Proteins)1WVN    1ZTG    3VKE   
CATH (Classification of proteins structures)1WVN    1ZTG    3VKE   
SuperfamilyQ15365
Human Protein AtlasENSG00000169564
Peptide AtlasQ15365
HPRD03128
IPIIPI00016610   
Protein Interaction databases
DIP (DOE-UCLA)Q15365
IntAct (EBI)Q15365
FunCoupENSG00000169564
BioGRIDPCBP1
STRING (EMBL)PCBP1
ZODIACPCBP1
Ontologies - Pathways
QuickGOQ15365
Ontology : AmiGOmRNA splicing, via spliceosome  P-body  RNA polymerase II transcription factor activity, sequence-specific DNA binding  single-stranded DNA binding  RNA binding  mRNA binding  protein binding  nucleoplasm  nucleoplasm  cytoplasm  cytosol  gene expression  membrane  nuclear speck  viral RNA genome replication  cadherin binding  positive regulation of transcription from RNA polymerase II promoter  extracellular exosome  sequence-specific single stranded DNA binding  
Ontology : EGO-EBImRNA splicing, via spliceosome  P-body  RNA polymerase II transcription factor activity, sequence-specific DNA binding  single-stranded DNA binding  RNA binding  mRNA binding  protein binding  nucleoplasm  nucleoplasm  cytoplasm  cytosol  gene expression  membrane  nuclear speck  viral RNA genome replication  cadherin binding  positive regulation of transcription from RNA polymerase II promoter  extracellular exosome  sequence-specific single stranded DNA binding  
Pathways : KEGGSpliceosome   
NDEx NetworkPCBP1
Atlas of Cancer Signalling NetworkPCBP1
Wikipedia pathwaysPCBP1
Orthology - Evolution
OrthoDB5093
GeneTree (enSembl)ENSG00000169564
Phylogenetic Trees/Animal Genes : TreeFamPCBP1
HOVERGENQ15365
HOGENOMQ15365
Homologs : HomoloGenePCBP1
Homology/Alignments : Family Browser (UCSC)PCBP1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPCBP1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PCBP1
dbVarPCBP1
ClinVarPCBP1
1000_GenomesPCBP1 
Exome Variant ServerPCBP1
ExAC (Exome Aggregation Consortium)PCBP1 (select the gene name)
Genetic variants : HAPMAP5093
Genomic Variants (DGV)PCBP1 [DGVbeta]
DECIPHERPCBP1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPCBP1 
Mutations
ICGC Data PortalPCBP1 
TCGA Data PortalPCBP1 
Broad Tumor PortalPCBP1
OASIS PortalPCBP1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPCBP1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPCBP1
intOGen PortalPCBP1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PCBP1
DgiDB (Drug Gene Interaction Database)PCBP1
DoCM (Curated mutations)PCBP1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PCBP1 (select a term)
intoGenPCBP1
Cancer3DPCBP1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601209   
Orphanet
MedgenPCBP1
Genetic Testing Registry PCBP1
NextProtQ15365 [Medical]
TSGene5093
GENETestsPCBP1
Huge Navigator PCBP1 [HugePedia]
snp3D : Map Gene to Disease5093
BioCentury BCIQPCBP1
ClinGenPCBP1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5093
Chemical/Pharm GKB GenePA32986
Clinical trialPCBP1
Miscellaneous
canSAR (ICR)PCBP1 (select the gene name)
Probes
Litterature
PubMed147 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePCBP1
EVEXPCBP1
GoPubMedPCBP1
iHOPPCBP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:30:25 CEST 2017

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