Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

PCCB (propionyl CoA carboxylase, beta polypeptide)

Identity

Alias_namespropionyl Coenzyme A carboxylase, beta polypeptide
Other alias-
HGNC (Hugo) PCCB
LocusID (NCBI) 5096
Atlas_Id 71694
Location 3q22.3  [Link to chromosome band 3q22]
Location_base_pair Starts at 135969167 and ends at 136049013 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
PCCB (3q22.3) / DLG1 (3q29)PCCB (3q22.3) / PCCB (3q22.3)PIK3CB (3q22.3) / PCCB (3q22.3)
RPL34 (4q25) / PCCB (3q22.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PCCB   8654
Cards
Entrez_Gene (NCBI)PCCB  5096  propionyl CoA carboxylase, beta polypeptide
Aliases
GeneCards (Weizmann)PCCB
Ensembl hg19 (Hinxton)ENSG00000114054 [Gene_View]  chr3:135969167-136049013 [Contig_View]  PCCB [Vega]
Ensembl hg38 (Hinxton)ENSG00000114054 [Gene_View]  chr3:135969167-136049013 [Contig_View]  PCCB [Vega]
ICGC DataPortalENSG00000114054
TCGA cBioPortalPCCB
AceView (NCBI)PCCB
Genatlas (Paris)PCCB
WikiGenes5096
SOURCE (Princeton)PCCB
Genetics Home Reference (NIH)PCCB
Genomic and cartography
GoldenPath hg19 (UCSC)PCCB  -     chr3:135969167-136049013 +  3q22.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)PCCB  -     3q22.3   [Description]    (hg38-Dec_2013)
EnsemblPCCB - 3q22.3 [CytoView hg19]  PCCB - 3q22.3 [CytoView hg38]
Mapping of homologs : NCBIPCCB [Mapview hg19]  PCCB [Mapview hg38]
OMIM232050   606054   
Gene and transcription
Genbank (Entrez)AB209009 AF217984 AI191766 AK130359 AK225215
RefSeq transcript (Entrez)NM_000532 NM_001178014
RefSeq genomic (Entrez)NC_000003 NC_018914 NG_008939 NT_005612 NW_004929311
Consensus coding sequences : CCDS (NCBI)PCCB
Cluster EST : UnigeneHs.63788 [ NCBI ]
CGAP (NCI)Hs.63788
Alternative Splicing GalleryENSG00000114054
Gene ExpressionPCCB [ NCBI-GEO ]   PCCB [ EBI - ARRAY_EXPRESS ]   PCCB [ SEEK ]   PCCB [ MEM ]
Gene Expression Viewer (FireBrowse)PCCB [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5096
GTEX Portal (Tissue expression)PCCB
Protein : pattern, domain, 3D structure
UniProt/SwissProtP05166   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP05166  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP05166
Splice isoforms : SwissVarP05166
Catalytic activity : Enzyme6.4.1.3 [ Enzyme-Expasy ]   6.4.1.36.4.1.3 [ IntEnz-EBI ]   6.4.1.3 [ BRENDA ]   6.4.1.3 [ KEGG ]   
PhosPhoSitePlusP05166
Domaine pattern : Prosite (Expaxy)COA_CT_CTER (PS50989)    COA_CT_NTER (PS50980)   
Domains : Interpro (EBI)Carboxyl_trans    ClpP/crotonase-like_dom    COA_CT_C    COA_CT_N   
Domain families : Pfam (Sanger)Carboxyl_trans (PF01039)   
Domain families : Pfam (NCBI)pfam01039   
Conserved Domain (NCBI)PCCB
DMDM Disease mutations5096
Blocks (Seattle)PCCB
SuperfamilyP05166
Human Protein AtlasENSG00000114054
Peptide AtlasP05166
HPRD01982
IPIIPI00007247   IPI00387103   IPI01021705   IPI00945117   IPI00921904   IPI00985361   IPI00945130   IPI00946409   IPI00947502   IPI00946553   IPI00946876   IPI00792361   IPI00945862   IPI00947356   IPI00947051   IPI00947150   
Protein Interaction databases
DIP (DOE-UCLA)P05166
IntAct (EBI)P05166
FunCoupENSG00000114054
BioGRIDPCCB
STRING (EMBL)PCCB
ZODIACPCCB
Ontologies - Pathways
QuickGOP05166
Ontology : AmiGOpropionyl-CoA carboxylase activity  ATP binding  mitochondrion  mitochondrial matrix  cytosol  fatty acid beta-oxidation  vitamin metabolic process  water-soluble vitamin metabolic process  biotin metabolic process  short-chain fatty acid catabolic process  cellular lipid metabolic process  small molecule metabolic process  
Ontology : EGO-EBIpropionyl-CoA carboxylase activity  ATP binding  mitochondrion  mitochondrial matrix  cytosol  fatty acid beta-oxidation  vitamin metabolic process  water-soluble vitamin metabolic process  biotin metabolic process  short-chain fatty acid catabolic process  cellular lipid metabolic process  small molecule metabolic process  
Pathways : KEGGValine, leucine and isoleucine degradation    Glyoxylate and dicarboxylate metabolism    Propanoate metabolism   
NDEx NetworkPCCB
Atlas of Cancer Signalling NetworkPCCB
Wikipedia pathwaysPCCB
Orthology - Evolution
OrthoDB5096
GeneTree (enSembl)ENSG00000114054
Phylogenetic Trees/Animal Genes : TreeFamPCCB
HOVERGENP05166
HOGENOMP05166
Homologs : HomoloGenePCCB
Homology/Alignments : Family Browser (UCSC)PCCB
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPCCB [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PCCB
dbVarPCCB
ClinVarPCCB
1000_GenomesPCCB 
Exome Variant ServerPCCB
ExAC (Exome Aggregation Consortium)PCCB (select the gene name)
Genetic variants : HAPMAP5096
Genomic Variants (DGV)PCCB [DGVbeta]
DECIPHER (Syndromes)3:135969167-136049013  ENSG00000114054
CONAN: Copy Number AnalysisPCCB 
Mutations
ICGC Data PortalPCCB 
TCGA Data PortalPCCB 
Broad Tumor PortalPCCB
OASIS PortalPCCB [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPCCB  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPCCB
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Mendelian genes
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch PCCB
DgiDB (Drug Gene Interaction Database)PCCB
DoCM (Curated mutations)PCCB (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PCCB (select a term)
intoGenPCCB
Cancer3DPCCB(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM232050    606054   
Orphanet3557   
MedgenPCCB
Genetic Testing Registry PCCB
NextProtP05166 [Medical]
TSGene5096
GENETestsPCCB
Huge Navigator PCCB [HugePedia]
snp3D : Map Gene to Disease5096
BioCentury BCIQPCCB
ClinGenPCCB
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5096
Chemical/Pharm GKB GenePA32993
Clinical trialPCCB
Miscellaneous
canSAR (ICR)PCCB (select the gene name)
Probes
Litterature
PubMed45 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePCCB
EVEXPCCB
GoPubMedPCCB
iHOPPCCB
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 12:37:54 CET 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.