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PCDHA8 (protocadherin alpha 8)

Identity

Other aliasPCDH-ALPHA8
HGNC (Hugo) PCDHA8
LocusID (NCBI) 56140
Atlas_Id 71715
Location 5q31.3  [Link to chromosome band 5q31]
Location_base_pair Starts at 140841322 and ends at 141012344 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ADAMTS17 (15q26.3) / PCDHA8 (5q31.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PCDHA8   8674
Cards
Entrez_Gene (NCBI)PCDHA8  56140  protocadherin alpha 8
AliasesPCDH-ALPHA8
GeneCards (Weizmann)PCDHA8
Ensembl hg19 (Hinxton)ENSG00000204962 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000204962 [Gene_View]  chr5:140841322-141012344 [Contig_View]  PCDHA8 [Vega]
ICGC DataPortalENSG00000204962
TCGA cBioPortalPCDHA8
AceView (NCBI)PCDHA8
Genatlas (Paris)PCDHA8
WikiGenes56140
SOURCE (Princeton)PCDHA8
Genetics Home Reference (NIH)PCDHA8
Genomic and cartography
GoldenPath hg38 (UCSC)PCDHA8  -     chr5:140841322-141012344 +  5q31.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PCDHA8  -     5q31.3   [Description]    (hg19-Feb_2009)
EnsemblPCDHA8 - 5q31.3 [CytoView hg19]  PCDHA8 - 5q31.3 [CytoView hg38]
Mapping of homologs : NCBIPCDHA8 [Mapview hg19]  PCDHA8 [Mapview hg38]
OMIM606314   
Gene and transcription
Genbank (Entrez)AF152316 AF152486 BC136749 BC136750
RefSeq transcript (Entrez)NM_018911 NM_031856
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PCDHA8
Cluster EST : UnigeneHs.199343 [ NCBI ]
CGAP (NCI)Hs.199343
Alternative Splicing GalleryENSG00000204962
Gene ExpressionPCDHA8 [ NCBI-GEO ]   PCDHA8 [ EBI - ARRAY_EXPRESS ]   PCDHA8 [ SEEK ]   PCDHA8 [ MEM ]
Gene Expression Viewer (FireBrowse)PCDHA8 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)56140
GTEX Portal (Tissue expression)PCDHA8
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y5H6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y5H6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y5H6
Splice isoforms : SwissVarQ9Y5H6
PhosPhoSitePlusQ9Y5H6
Domaine pattern : Prosite (Expaxy)CADHERIN_1 (PS00232)    CADHERIN_2 (PS50268)   
Domains : Interpro (EBI)Cadherin    Cadherin-like    Cadherin_CBD    Cadherin_CS    Cadherin_N   
Domain families : Pfam (Sanger)Cadherin (PF00028)    Cadherin_2 (PF08266)    Cadherin_tail (PF15974)   
Domain families : Pfam (NCBI)pfam00028    pfam08266    pfam15974   
Domain families : Smart (EMBL)CA (SM00112)  
Conserved Domain (NCBI)PCDHA8
DMDM Disease mutations56140
Blocks (Seattle)PCDHA8
SuperfamilyQ9Y5H6
Human Protein AtlasENSG00000204962
Peptide AtlasQ9Y5H6
HPRD07326
IPIIPI00001495   IPI00221023   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y5H6
IntAct (EBI)Q9Y5H6
FunCoupENSG00000204962
BioGRIDPCDHA8
STRING (EMBL)PCDHA8
ZODIACPCDHA8
Ontologies - Pathways
QuickGOQ9Y5H6
Ontology : AmiGOcalcium ion binding  integral component of plasma membrane  cell adhesion  homophilic cell adhesion via plasma membrane adhesion molecules  cell-cell signaling  nervous system development  
Ontology : EGO-EBIcalcium ion binding  integral component of plasma membrane  cell adhesion  homophilic cell adhesion via plasma membrane adhesion molecules  cell-cell signaling  nervous system development  
NDEx NetworkPCDHA8
Atlas of Cancer Signalling NetworkPCDHA8
Wikipedia pathwaysPCDHA8
Orthology - Evolution
OrthoDB56140
GeneTree (enSembl)ENSG00000204962
Phylogenetic Trees/Animal Genes : TreeFamPCDHA8
HOVERGENQ9Y5H6
HOGENOMQ9Y5H6
Homologs : HomoloGenePCDHA8
Homology/Alignments : Family Browser (UCSC)PCDHA8
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPCDHA8 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PCDHA8
dbVarPCDHA8
ClinVarPCDHA8
1000_GenomesPCDHA8 
Exome Variant ServerPCDHA8
ExAC (Exome Aggregation Consortium)PCDHA8 (select the gene name)
Genetic variants : HAPMAP56140
Genomic Variants (DGV)PCDHA8 [DGVbeta]
DECIPHERPCDHA8 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPCDHA8 
Mutations
ICGC Data PortalPCDHA8 
TCGA Data PortalPCDHA8 
Broad Tumor PortalPCDHA8
OASIS PortalPCDHA8 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPCDHA8  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPCDHA8
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PCDHA8
DgiDB (Drug Gene Interaction Database)PCDHA8
DoCM (Curated mutations)PCDHA8 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PCDHA8 (select a term)
intoGenPCDHA8
Cancer3DPCDHA8(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606314   
Orphanet
MedgenPCDHA8
Genetic Testing Registry PCDHA8
NextProtQ9Y5H6 [Medical]
TSGene56140
GENETestsPCDHA8
Target ValidationPCDHA8
Huge Navigator PCDHA8 [HugePedia]
snp3D : Map Gene to Disease56140
BioCentury BCIQPCDHA8
ClinGenPCDHA8
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD56140
Chemical/Pharm GKB GenePA33020
Clinical trialPCDHA8
Miscellaneous
canSAR (ICR)PCDHA8 (select the gene name)
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePCDHA8
EVEXPCDHA8
GoPubMedPCDHA8
iHOPPCDHA8
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:34:04 CEST 2017

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