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PCF11 (PCF11 cleavage and polyadenylation factor subunit)

Identity

Alias (NCBI)-
HGNC (Hugo) PCF11
HGNC Alias symbKIAA0824
HGNC Previous namePCF11, cleavage and polyadenylation factor II subunit, homolog (S. cerevisiae)
 PCF11, cleavage and polyadenylation factor subunit, homolog (S. cerevisiae)
LocusID (NCBI) 51585
Atlas_Id 71759
Location 11q14.1  [Link to chromosome band 11q14]
Location_base_pair Starts at 83157131 and ends at 83187451 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
PCF11 (11q14.1)::ANK2 (4q25)PCF11 (11q14.1)::KDM2A (11q13.2)PCF11 (11q14.1)::PCF11 (11q14.1)
PCF11 (11q14.1)::SPON1 (11p15.2)SPAG17 (1p12)::PCF11 (11q14.1)PCF11 SPON1
PCF11 KDM2A

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)PCF11   30097
Cards
Entrez_Gene (NCBI)PCF11    PCF11 cleavage and polyadenylation factor subunit
Aliases
GeneCards (Weizmann)PCF11
Ensembl hg19 (Hinxton)ENSG00000165494 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000165494 [Gene_View]  ENSG00000165494 [Sequence]  chr11:83157131-83187451 [Contig_View]  PCF11 [Vega]
ICGC DataPortalENSG00000165494
TCGA cBioPortalPCF11
AceView (NCBI)PCF11
Genatlas (Paris)PCF11
SOURCE (Princeton)PCF11
Genetics Home Reference (NIH)PCF11
Genomic and cartography
GoldenPath hg38 (UCSC)PCF11  -     chr11:83157131-83187451 +  11q14.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PCF11  -     11q14.1   [Description]    (hg19-Feb_2009)
GoldenPathPCF11 - 11q14.1 [CytoView hg19]  PCF11 - 11q14.1 [CytoView hg38]
ImmunoBaseENSG00000165494
Genome Data Viewer NCBIPCF11 [Mapview hg19]  
OMIM608876   
Gene and transcription
Genbank (Entrez)AB020631 AF046935 AF086097 AK025103 AK302606
RefSeq transcript (Entrez)NM_001346413 NM_001346414 NM_001346415 NM_015885
Consensus coding sequences : CCDS (NCBI)PCF11
Gene ExpressionPCF11 [ NCBI-GEO ]   PCF11 [ EBI - ARRAY_EXPRESS ]   PCF11 [ SEEK ]   PCF11 [ MEM ]
Gene Expression Viewer (FireBrowse)PCF11 [ Firebrowse - Broad ]
GenevisibleExpression of PCF11 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51585
GTEX Portal (Tissue expression)PCF11
Human Protein AtlasENSG00000165494-PCF11 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO94913   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO94913  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO94913
PhosPhoSitePlusO94913
Domaine pattern : Prosite (Expaxy)CID (PS51391)   
Domains : Interpro (EBI)CID_dom    ENTH_VHS   
Domain families : Pfam (Sanger)CID (PF04818)   
Domain families : Pfam (NCBI)pfam04818   
Domain families : Smart (EMBL)RPR (SM00582)  
Conserved Domain (NCBI)PCF11
PDB (RSDB)6WJH   
PDB Europe6WJH   
PDB (PDBSum)6WJH   
PDB (IMB)6WJH   
Structural Biology KnowledgeBase6WJH   
SCOP (Structural Classification of Proteins)6WJH   
CATH (Classification of proteins structures)6WJH   
SuperfamilyO94913
AlphaFold pdb e-kbO94913   
Human Protein Atlas [tissue]ENSG00000165494-PCF11 [tissue]
HPRD10592
Protein Interaction databases
DIP (DOE-UCLA)O94913
IntAct (EBI)O94913
BioGRIDPCF11
STRING (EMBL)PCF11
ZODIACPCF11
Ontologies - Pathways
QuickGOO94913
Ontology : AmiGOmRNA splicing, via spliceosome  RNA polymerase II complex binding  mRNA binding  nucleoplasm  nucleoplasm  cytoplasm  mitochondrion  mRNA cleavage factor complex  mRNA cleavage factor complex  termination of RNA polymerase II transcription  termination of RNA polymerase II transcription  mRNA polyadenylation  mRNA cleavage  mRNA 3'-end processing  
Ontology : EGO-EBImRNA splicing, via spliceosome  RNA polymerase II complex binding  mRNA binding  nucleoplasm  nucleoplasm  cytoplasm  mitochondrion  mRNA cleavage factor complex  mRNA cleavage factor complex  termination of RNA polymerase II transcription  termination of RNA polymerase II transcription  mRNA polyadenylation  mRNA cleavage  mRNA 3'-end processing  
NDEx NetworkPCF11
Atlas of Cancer Signalling NetworkPCF11
Wikipedia pathwaysPCF11
Orthology - Evolution
OrthoDB51585
GeneTree (enSembl)ENSG00000165494
Phylogenetic Trees/Animal Genes : TreeFamPCF11
Homologs : HomoloGenePCF11
Homology/Alignments : Family Browser (UCSC)PCF11
Gene fusions - Rearrangements
Fusion : QuiverPCF11
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPCF11 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PCF11
dbVarPCF11
ClinVarPCF11
MonarchPCF11
1000_GenomesPCF11 
Exome Variant ServerPCF11
GNOMAD BrowserENSG00000165494
Varsome BrowserPCF11
ACMGPCF11 variants
VarityO94913
Genomic Variants (DGV)PCF11 [DGVbeta]
DECIPHERPCF11 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPCF11 
Mutations
ICGC Data PortalPCF11 
TCGA Data PortalPCF11 
Broad Tumor PortalPCF11
OASIS PortalPCF11 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPCF11  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DPCF11
Mutations and Diseases : HGMDPCF11
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaPCF11
DgiDB (Drug Gene Interaction Database)PCF11
DoCM (Curated mutations)PCF11
CIViC (Clinical Interpretations of Variants in Cancer)PCF11
Cancer3DPCF11
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608876   
Orphanet
DisGeNETPCF11
MedgenPCF11
Genetic Testing Registry PCF11
NextProtO94913 [Medical]
GENETestsPCF11
Target ValidationPCF11
Huge Navigator PCF11 [HugePedia]
ClinGenPCF11
Clinical trials, drugs, therapy
MyCancerGenomePCF11
Protein Interactions : CTDPCF11
Pharm GKB GenePA142671196
PharosO94913
Clinical trialPCF11
Miscellaneous
canSAR (ICR)PCF11
HarmonizomePCF11
ARCHS4PCF11
DataMed IndexPCF11
Probes
Litterature
PubMed43 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXPCF11
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sun Jan 16 19:19:09 CET 2022

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