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PCGF5 (polycomb group ring finger 5)

Identity

Alias (NCBI)RNF159
HGNC (Hugo) PCGF5
HGNC Alias symbMGC16202
HGNC Previous nameRNF159
HGNC Previous namering finger protein (C3HC4 type) 159
LocusID (NCBI) 84333
Atlas_Id 46683
Location 10q23.32  [Link to chromosome band 10q23]
Location_base_pair Starts at 91220663 and ends at 91284337 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CASP8 (2q33.1) / PCGF5 (10q23.32)HECTD2 (10q23.32) / PCGF5 (10q23.32)TRPS1 (8q23.3) / PCGF5 (10q23.32)
HECTD2 10q23.32 / PCGF5 10q23.32

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)PCGF5   28264
Cards
Entrez_Gene (NCBI)PCGF5    polycomb group ring finger 5
AliasesRNF159
GeneCards (Weizmann)PCGF5
Ensembl hg19 (Hinxton)ENSG00000180628 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000180628 [Gene_View]  ENSG00000180628 [Sequence]  chr10:91220663-91284337 [Contig_View]  PCGF5 [Vega]
ICGC DataPortalENSG00000180628
TCGA cBioPortalPCGF5
AceView (NCBI)PCGF5
Genatlas (Paris)PCGF5
SOURCE (Princeton)PCGF5
Genetics Home Reference (NIH)PCGF5
Genomic and cartography
GoldenPath hg38 (UCSC)PCGF5  -     chr10:91220663-91284337 +  10q23.32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PCGF5  -     10q23.32   [Description]    (hg19-Feb_2009)
GoldenPathPCGF5 - 10q23.32 [CytoView hg19]  PCGF5 - 10q23.32 [CytoView hg38]
ImmunoBaseENSG00000180628
Genome Data Viewer NCBIPCGF5 [Mapview hg19]  
OMIM617407   
Gene and transcription
Genbank (Entrez)AK055625 AK303014 AL832003 AL832496 BC007377
RefSeq transcript (Entrez)NM_001256549 NM_001257101 NM_032373
Consensus coding sequences : CCDS (NCBI)PCGF5
Gene ExpressionPCGF5 [ NCBI-GEO ]   PCGF5 [ EBI - ARRAY_EXPRESS ]   PCGF5 [ SEEK ]   PCGF5 [ MEM ]
Gene Expression Viewer (FireBrowse)PCGF5 [ Firebrowse - Broad ]
GenevisibleExpression of PCGF5 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84333
GTEX Portal (Tissue expression)PCGF5
Human Protein AtlasENSG00000180628-PCGF5 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86SE9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86SE9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86SE9
PhosPhoSitePlusQ86SE9
Domaine pattern : Prosite (Expaxy)ZF_RING_1 (PS00518)    ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)RAWUL    Znf_RING    Znf_RING/FYVE/PHD    Znf_RING_CS   
Domain families : Pfam (Sanger)RAWUL (PF16207)   
Domain families : Pfam (NCBI)pfam16207   
Domain families : Smart (EMBL)RING (SM00184)  
Conserved Domain (NCBI)PCGF5
PDB (RSDB)4S3O   
PDB Europe4S3O   
PDB (PDBSum)4S3O   
PDB (IMB)4S3O   
Structural Biology KnowledgeBase4S3O   
SCOP (Structural Classification of Proteins)4S3O   
CATH (Classification of proteins structures)4S3O   
SuperfamilyQ86SE9
AlphaFold pdb e-kbQ86SE9   
Human Protein Atlas [tissue]ENSG00000180628-PCGF5 [tissue]
HPRD17825
Protein Interaction databases
DIP (DOE-UCLA)Q86SE9
IntAct (EBI)Q86SE9
BioGRIDPCGF5
STRING (EMBL)PCGF5
ZODIACPCGF5
Ontologies - Pathways
QuickGOQ86SE9
Ontology : AmiGOX chromosome  protein binding  nucleus  nucleoplasm  Golgi apparatus  centrosome  regulation of transcription by RNA polymerase II  PcG protein complex  PRC1 complex  histone H2A-K119 monoubiquitination  histone H2A-K119 monoubiquitination  positive regulation of transcription by RNA polymerase II  metal ion binding  inactivation of X chromosome by genetic imprinting  inactivation of X chromosome by genetic imprinting  
Ontology : EGO-EBIX chromosome  protein binding  nucleus  nucleoplasm  Golgi apparatus  centrosome  regulation of transcription by RNA polymerase II  PcG protein complex  PRC1 complex  histone H2A-K119 monoubiquitination  histone H2A-K119 monoubiquitination  positive regulation of transcription by RNA polymerase II  metal ion binding  inactivation of X chromosome by genetic imprinting  inactivation of X chromosome by genetic imprinting  
NDEx NetworkPCGF5
Atlas of Cancer Signalling NetworkPCGF5
Wikipedia pathwaysPCGF5
Orthology - Evolution
OrthoDB84333
GeneTree (enSembl)ENSG00000180628
Phylogenetic Trees/Animal Genes : TreeFamPCGF5
Homologs : HomoloGenePCGF5
Homology/Alignments : Family Browser (UCSC)PCGF5
Gene fusions - Rearrangements
Fusion : MitelmanHECTD2/PCGF5 [10q23.32/10q23.32]  
Fusion : QuiverPCGF5
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPCGF5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PCGF5
dbVarPCGF5
ClinVarPCGF5
MonarchPCGF5
1000_GenomesPCGF5 
Exome Variant ServerPCGF5
GNOMAD BrowserENSG00000180628
Varsome BrowserPCGF5
ACMGPCGF5 variants
VarityQ86SE9
Genomic Variants (DGV)PCGF5 [DGVbeta]
DECIPHERPCGF5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPCGF5 
Mutations
ICGC Data PortalPCGF5 
TCGA Data PortalPCGF5 
Broad Tumor PortalPCGF5
OASIS PortalPCGF5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPCGF5  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DPCGF5
Mutations and Diseases : HGMDPCGF5
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaPCGF5
DgiDB (Drug Gene Interaction Database)PCGF5
DoCM (Curated mutations)PCGF5
CIViC (Clinical Interpretations of Variants in Cancer)PCGF5
Cancer3DPCGF5
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM617407   
Orphanet
DisGeNETPCGF5
MedgenPCGF5
Genetic Testing Registry PCGF5
NextProtQ86SE9 [Medical]
GENETestsPCGF5
Target ValidationPCGF5
Huge Navigator PCGF5 [HugePedia]
ClinGenPCGF5
Clinical trials, drugs, therapy
MyCancerGenomePCGF5
Protein Interactions : CTDPCGF5
Pharm GKB GenePA134929149
PharosQ86SE9
Clinical trialPCGF5
Miscellaneous
canSAR (ICR)PCGF5
HarmonizomePCGF5
DataMed IndexPCGF5
Probes
Litterature
PubMed37 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXPCGF5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:24:36 CEST 2021

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