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PCGF6 (polycomb group ring finger 6)

Identity

Alias_namesRNF134
ring finger protein 134
Alias_symbol (synonym)MBLR
Other alias
HGNC (Hugo) PCGF6
LocusID (NCBI) 84108
Atlas_Id 46905
Location 10q24.33  [Link to chromosome band 10q24]
Location_base_pair Starts at 105062553 and ends at 105110891 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
PALLD (4q32.3) / PCGF6 (10q24.33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PCGF6   21156
Cards
Entrez_Gene (NCBI)PCGF6  84108  polycomb group ring finger 6
AliasesMBLR; RNF134
GeneCards (Weizmann)PCGF6
Ensembl hg19 (Hinxton)ENSG00000156374 [Gene_View]  chr10:105062553-105110891 [Contig_View]  PCGF6 [Vega]
Ensembl hg38 (Hinxton)ENSG00000156374 [Gene_View]  chr10:105062553-105110891 [Contig_View]  PCGF6 [Vega]
ICGC DataPortalENSG00000156374
TCGA cBioPortalPCGF6
AceView (NCBI)PCGF6
Genatlas (Paris)PCGF6
WikiGenes84108
SOURCE (Princeton)PCGF6
Genetics Home Reference (NIH)PCGF6
Genomic and cartography
GoldenPath hg19 (UCSC)PCGF6  -     chr10:105062553-105110891 -  10q24.33   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)PCGF6  -     10q24.33   [Description]    (hg38-Dec_2013)
EnsemblPCGF6 - 10q24.33 [CytoView hg19]  PCGF6 - 10q24.33 [CytoView hg38]
Mapping of homologs : NCBIPCGF6 [Mapview hg19]  PCGF6 [Mapview hg38]
OMIM607816   
Gene and transcription
Genbank (Entrez)AB047006 AK027885 AK290679 AK309105 BC007602
RefSeq transcript (Entrez)NM_001011663 NM_032154
RefSeq genomic (Entrez)NC_000010 NC_018921 NT_030059 NW_004929376
Consensus coding sequences : CCDS (NCBI)PCGF6
Cluster EST : UnigeneHs.335808 [ NCBI ]
CGAP (NCI)Hs.335808
Alternative Splicing GalleryENSG00000156374
Gene ExpressionPCGF6 [ NCBI-GEO ]   PCGF6 [ EBI - ARRAY_EXPRESS ]   PCGF6 [ SEEK ]   PCGF6 [ MEM ]
Gene Expression Viewer (FireBrowse)PCGF6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84108
GTEX Portal (Tissue expression)PCGF6
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BYE7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BYE7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BYE7
Splice isoforms : SwissVarQ9BYE7
PhosPhoSitePlusQ9BYE7
Domaine pattern : Prosite (Expaxy)ZF_RING_1 (PS00518)    ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)RAWUL    Ubiquitin-rel_dom    Znf_C3HC4_RING-type    Znf_RING    Znf_RING/FYVE/PHD    Znf_RING_CS   
Domain families : Pfam (Sanger)RAWUL (PF16207)    zf-C3HC4 (PF00097)   
Domain families : Pfam (NCBI)pfam16207    pfam00097   
Domain families : Smart (EMBL)RING (SM00184)  
Conserved Domain (NCBI)PCGF6
DMDM Disease mutations84108
Blocks (Seattle)PCGF6
PDB (SRS)2DJB   
PDB (PDBSum)2DJB   
PDB (IMB)2DJB   
PDB (RSDB)2DJB   
Structural Biology KnowledgeBase2DJB   
SCOP (Structural Classification of Proteins)2DJB   
CATH (Classification of proteins structures)2DJB   
SuperfamilyQ9BYE7
Human Protein AtlasENSG00000156374
Peptide AtlasQ9BYE7
HPRD07427
IPIIPI00063571   IPI00030334   
Protein Interaction databases
DIP (DOE-UCLA)Q9BYE7
IntAct (EBI)Q9BYE7
FunCoupENSG00000156374
BioGRIDPCGF6
STRING (EMBL)PCGF6
ZODIACPCGF6
Ontologies - Pathways
QuickGOQ9BYE7
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II regulatory region sequence-specific DNA binding  transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding  DNA binding  transcription factor activity, sequence-specific DNA binding  protein binding  nucleus  transcription, DNA-templated  zinc ion binding  PcG protein complex  PcG protein complex  PRC1 complex  negative regulation of transcription, DNA-templated  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II regulatory region sequence-specific DNA binding  transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding  DNA binding  transcription factor activity, sequence-specific DNA binding  protein binding  nucleus  transcription, DNA-templated  zinc ion binding  PcG protein complex  PcG protein complex  PRC1 complex  negative regulation of transcription, DNA-templated  
NDEx NetworkPCGF6
Atlas of Cancer Signalling NetworkPCGF6
Wikipedia pathwaysPCGF6
Orthology - Evolution
OrthoDB84108
GeneTree (enSembl)ENSG00000156374
Phylogenetic Trees/Animal Genes : TreeFamPCGF6
HOVERGENQ9BYE7
HOGENOMQ9BYE7
Homologs : HomoloGenePCGF6
Homology/Alignments : Family Browser (UCSC)PCGF6
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPCGF6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PCGF6
dbVarPCGF6
ClinVarPCGF6
1000_GenomesPCGF6 
Exome Variant ServerPCGF6
ExAC (Exome Aggregation Consortium)PCGF6 (select the gene name)
Genetic variants : HAPMAP84108
Genomic Variants (DGV)PCGF6 [DGVbeta]
DECIPHER (Syndromes)10:105062553-105110891  ENSG00000156374
CONAN: Copy Number AnalysisPCGF6 
Mutations
ICGC Data PortalPCGF6 
TCGA Data PortalPCGF6 
Broad Tumor PortalPCGF6
OASIS PortalPCGF6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPCGF6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPCGF6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PCGF6
DgiDB (Drug Gene Interaction Database)PCGF6
DoCM (Curated mutations)PCGF6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PCGF6 (select a term)
intoGenPCGF6
Cancer3DPCGF6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607816   
Orphanet
MedgenPCGF6
Genetic Testing Registry PCGF6
NextProtQ9BYE7 [Medical]
TSGene84108
GENETestsPCGF6
Huge Navigator PCGF6 [HugePedia]
snp3D : Map Gene to Disease84108
BioCentury BCIQPCGF6
ClinGenPCGF6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84108
Chemical/Pharm GKB GenePA134887110
Clinical trialPCGF6
Miscellaneous
canSAR (ICR)PCGF6 (select the gene name)
Probes
Litterature
PubMed34 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePCGF6
EVEXPCGF6
GoPubMedPCGF6
iHOPPCGF6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:13:45 CEST 2017

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