PCIF1 (phosphorylated CTD interacting factor 1)

2014-11-01  

Identity

HGNC
LOCATION
20q13.12
LOCUSID
ALIAS
C20orf67,CAPAM,PPP1R121,hCAPAM,hPCIF1
FUSION GENES

Other Information

Locus ID:

NCBI: 63935
MIM: 618626
HGNC: 16200
Ensembl: ENSG00000100982

Variants:

dbSNP: 63935
ClinVar: 63935
TCGA: ENSG00000100982
COSMIC: PCIF1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000100982ENST00000372409Q9H4Z3
ENSG00000100982ENST00000479348A0A087WWZ2

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
304671782019Cap-specific terminal N 6-methylation of RNA by an RNA polymerase II-associated methyltransferase.44
304875542019Cap-specific, terminal N6-methylation by a mammalian m6Am methyltransferase.24
312796582019Identification of the m6Am Methyltransferase PCIF1 Reveals the Location and Functions of m6Am in the Transcriptome.14
125658712003PCIF1, a novel human WW domain-containing protein, interacts with the phosphorylated RNA polymerase II.11
312796592019PCIF1 Catalyzes m6Am mRNA Methylation to Regulate Gene Expression.11
182944532008Human phosphorylated CTD-interacting protein, PCIF1, negatively modulates gene expression by RNA polymerase II.6
318226642019Atlas of quantitative single-base-resolution N6-methyl-adenine methylomes.2
196820922009Prolyl isomerase Pin1 shares functional similarity with phosphorylated CTD interacting factor PCIF1 in vertebrate cells.1

Citation

Dessen P

PCIF1 (phosphorylated CTD interacting factor 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/71761/pcif1