Atlas of Genetics and Cytogenetics in Oncology and Haematology

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PCM1 (pericentriolar material 1)


Alias (NCBI)PTC4
HGNC (Hugo) PCM1
HGNC Alias symbPTC4
LocusID (NCBI) 5108
Atlas_Id 41668
Location 8p22  [Link to chromosome band 8p22]
Location_base_pair Starts at 17922988 and ends at 18029948 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ASAH1 (8p22)::PCM1 (8p22)CCDC14 (3q21.1)::PCM1 (8p22)CREB3L2 (7q33)::PCM1 (8p22)
ERICH1 (8p23.3)::PCM1 (8p22)JAK2 (9p24.1)::PCM1 (8p22)PCM1 (8p22)::FGL1 (8p22)
PCM1 (8p22)::JAK2 (9p24.1)PCM1 (8p22)::NRG1 (8p12)PCM1 (8p22)::PCM1 (8p22)
PCM1 (8p22)::RET (10q11.21)PODXL2 (3q21.3)::PCM1 (8p22)RET (10q11.21)::PCM1 (8p22)
JAK2 9p24.1::PCM1 8p22PCM1 8p22::JAK2 9p24.1PCM1 8p22::RET 10q11.21
ERICH1 8p23.3::PCM1 8p22PCM1 8p22::NRG1 8p12


Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute





Other Leukemias implicated (Data extracted from papers in the Atlas) [ 8 ]
  Chronic Eosinophilic Leukemia-Not Otherwise Specified (CEL-NOS)::Idiopathic Hypereosinophilic Syndrome (IHES)
Myeloid::Lymphoid neoplasms with abnormalities of PDGFRA
Myeloid::Lymphoid neoplasms with abnormalities of PDGFRB
Myeloid::lymphoid neoplasms with eosinophilia and rearrangement of PDGFRA, PDGFRB, or FGFR1, or with PCM1-JAK2: Overview 2019
t(5;9)(q14.1;p24) SSBP2::JAK2
t(5;14)(q33;q24) NIN::PDGFRB
t(8;9)(p22;p24) PCM1::JAK2
T-lineage acute lymphoblastic leukemia (T-ALL)

External links

HGNC (Hugo)PCM1   8727
Entrez_Gene (NCBI)PCM1    pericentriolar material 1
AliasesPTC4; RET/PCM-1
GeneCards (Weizmann)PCM1
Ensembl hg19 (Hinxton)ENSG00000078674 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000078674 [Gene_View]  ENSG00000078674 [Sequence]  chr8:17922988-18029948 [Contig_View]  PCM1 [Vega]
ICGC DataPortalENSG00000078674
TCGA cBioPortalPCM1
AceView (NCBI)PCM1
Genatlas (Paris)PCM1
SOURCE (Princeton)PCM1
Genetics Home Reference (NIH)PCM1
Genomic and cartography
GoldenPath hg38 (UCSC)PCM1  -     chr8:17922988-18029948 +  8p22   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PCM1  -     8p22   [Description]    (hg19-Feb_2009)
GoldenPathPCM1 - 8p22 [CytoView hg19]  PCM1 - 8p22 [CytoView hg38]
Genome Data Viewer NCBIPCM1 [Mapview hg19]  
Gene and transcription
Genbank (Entrez)AA931266 AF068293 AI810388 AI924817 AK091406
RefSeq transcript (Entrez)NM_001315507 NM_001315508 NM_001352632 NM_001352633 NM_001352634 NM_001352635 NM_001352636 NM_001352637 NM_001352638 NM_001352639 NM_001352640 NM_001352641 NM_001352642 NM_001352643 NM_001352644 NM_001352645 NM_001352646 NM_001352647 NM_001352648 NM_001352649 NM_001352650 NM_001352651 NM_001352652 NM_001352653 NM_001352654 NM_001352655 NM_001352656 NM_001352657 NM_001352658 NM_001352659 NM_001352660 NM_006197
Consensus coding sequences : CCDS (NCBI)PCM1
Gene ExpressionPCM1 [ NCBI-GEO ]   PCM1 [ EBI - ARRAY_EXPRESS ]   PCM1 [ SEEK ]   PCM1 [ MEM ]
Gene Expression Viewer (FireBrowse)PCM1 [ Firebrowse - Broad ]
GenevisibleExpression of PCM1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5108
GTEX Portal (Tissue expression)PCM1
Human Protein AtlasENSG00000078674-PCM1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)PCM1
Human Protein Atlas [tissue]ENSG00000078674-PCM1 [tissue]
Protein Interaction databases
Ontologies - Pathways
PubMed160 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Jan 20 12:51:29 CET 2022

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