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PCNT (pericentrin)

Identity

Other namesKEN
MOPD2
PCN
PCNT2
PCNTB
PCTN2
SCKL4
HGNC (Hugo) PCNT
LocusID (NCBI) 5116
Atlas_Id 46563
Location 21q22.3  [Link to chromosome band 21q22]
Location_base_pair Starts at 47744802 and ends at 47865682 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ADIPOQ (3q27.3) / PCNT (21q22.3)FAIM2 (12q13.12) / PCNT (21q22.3)PCNT (21q22.3) / HNRNPU (1q44)
PCNT (21q22.3) / MCOLN1 (19p13.2)PCNT (21q22.3) / POC1A (3p21.2)SLC37A1 (21q22.3) / PCNT (21q22.3)
USP25 (21q21.1) / PCNT (21q22.3)PCNT 21q22.3 / MCOLN1 19p13.2PCNT 21q22.3 / POC1A 3p21.2
SLC37A1 21q22.3 / PCNT 21q22.3USP25 21q21.1 / PCNT 21q22.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PCNT   16068
Cards
Entrez_Gene (NCBI)PCNT  5116  pericentrin
AliasesKEN; MOPD2; PCN; PCNT2; 
PCNTB; PCTN2; SCKL4
GeneCards (Weizmann)PCNT
Ensembl hg19 (Hinxton)ENSG00000160299 [Gene_View]  chr21:47744802-47865682 [Contig_View]  PCNT [Vega]
Ensembl hg38 (Hinxton)ENSG00000160299 [Gene_View]  chr21:47744802-47865682 [Contig_View]  PCNT [Vega]
ICGC DataPortalENSG00000160299
TCGA cBioPortalPCNT
AceView (NCBI)PCNT
Genatlas (Paris)PCNT
WikiGenes5116
SOURCE (Princeton)PCNT
Genomic and cartography
GoldenPath hg19 (UCSC)PCNT  -     chr21:47744802-47865682 +  21q22.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)PCNT  -     21q22.3   [Description]    (hg38-Dec_2013)
EnsemblPCNT - 21q22.3 [CytoView hg19]  PCNT - 21q22.3 [CytoView hg38]
Mapping of homologs : NCBIPCNT [Mapview hg19]  PCNT [Mapview hg38]
OMIM210720   605925   
Gene and transcription
Genbank (Entrez)AB007862 AF515282 AK024009 AK093923 AK296731
RefSeq transcript (Entrez)NM_001315529 NM_006031
RefSeq genomic (Entrez)NC_000021 NC_018932 NG_008961 NT_011512 NW_004929427
Consensus coding sequences : CCDS (NCBI)PCNT
Cluster EST : UnigeneHs.474069 [ NCBI ]
CGAP (NCI)Hs.474069
Alternative Splicing GalleryENSG00000160299
Gene ExpressionPCNT [ NCBI-GEO ]   PCNT [ EBI - ARRAY_EXPRESS ]   PCNT [ SEEK ]   PCNT [ MEM ]
Gene Expression Viewer (FireBrowse)PCNT [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5116
GTEX Portal (Tissue expression)PCNT
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95613 (Uniprot)
NextProtO95613  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95613
Splice isoforms : SwissVarO95613 (Swissvar)
PhosPhoSitePlusO95613
Domains : Interpro (EBI)PACT_domain    Pericentrin   
Domain families : Pfam (Sanger)PACT_coil_coil (PF10495)   
Domain families : Pfam (NCBI)pfam10495   
DMDM Disease mutations5116
Blocks (Seattle)PCNT
SuperfamilyO95613
Human Protein AtlasENSG00000160299
Peptide AtlasO95613
HPRD05804
IPIIPI00479143   IPI00973279   IPI00794771   IPI00220259   IPI00795262   
Protein Interaction databases
DIP (DOE-UCLA)O95613
IntAct (EBI)O95613
FunCoupENSG00000160299
BioGRIDPCNT
STRING (EMBL)PCNT
ZODIACPCNT
Ontologies - Pathways
QuickGOO95613
Ontology : AmiGOG2/M transition of mitotic cell cycle  microtubule cytoskeleton organization  protein binding  calmodulin binding  cytoplasm  centrosome  centriole  cytosol  microtubule  mitotic spindle organization  membrane  centriolar satellite  cilium assembly  positive regulation of intracellular protein transport  
Ontology : EGO-EBIG2/M transition of mitotic cell cycle  microtubule cytoskeleton organization  protein binding  calmodulin binding  cytoplasm  centrosome  centriole  cytosol  microtubule  mitotic spindle organization  membrane  centriolar satellite  cilium assembly  positive regulation of intracellular protein transport  
Pathways : BIOCARTAProtein Kinase A at the Centrosome [Genes]   
NDEx NetworkPCNT
Atlas of Cancer Signalling NetworkPCNT
Wikipedia pathwaysPCNT
Orthology - Evolution
OrthoDB5116
GeneTree (enSembl)ENSG00000160299
Phylogenetic Trees/Animal Genes : TreeFamPCNT
Homologs : HomoloGenePCNT
Homology/Alignments : Family Browser (UCSC)PCNT
Gene fusions - Rearrangements
Fusion: TCGAPCNT 21q22.3 MCOLN1 19p13.2 BRCA
Fusion: TCGAPCNT 21q22.3 POC1A 3p21.2 HNSC
Fusion: TCGASLC37A1 21q22.3 PCNT 21q22.3 BRCA
Fusion: TCGAUSP25 21q21.1 PCNT 21q22.3 HNSC
Polymorphisms : SNP, variants
NCBI Variation ViewerPCNT [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PCNT
dbVarPCNT
ClinVarPCNT
1000_GenomesPCNT 
Exome Variant ServerPCNT
ExAC (Exome Aggregation Consortium)PCNT (select the gene name)
Genetic variants : HAPMAP5116
Genomic Variants (DGV)PCNT [DGVbeta]
Mutations
ICGC Data PortalPCNT 
TCGA Data PortalPCNT 
Broad Tumor PortalPCNT
OASIS PortalPCNT [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPCNT 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
BioMutasearch PCNT
DgiDB (Drug Gene Interaction Database)PCNT
DoCM (Curated mutations)PCNT (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PCNT (select a term)
intoGenPCNT
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)21:47744802-47865682  ENSG00000160299
CONAN: Copy Number AnalysisPCNT 
Mutations and Diseases : HGMDPCNT
OMIM210720    605925   
MedgenPCNT
Genetic Testing Registry PCNT
NextProtO95613 [Medical]
TSGene5116
GENETestsPCNT
Huge Navigator PCNT [HugePedia]
snp3D : Map Gene to Disease5116
BioCentury BCIQPCNT
ClinGenPCNT
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5116
Chemical/Pharm GKB GenePA33079
Clinical trialPCNT
Miscellaneous
canSAR (ICR)PCNT (select the gene name)
Probes
Litterature
PubMed75 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePCNT
EVEXPCNT
GoPubMedPCNT
iHOPPCNT
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 19 19:06:28 CEST 2016

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