Atlas of Genetics and Cytogenetics in Oncology and Haematology


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PCYOX1 (prenylcysteine oxidase 1)

Identity

Alias_symbol (synonym)KIAA0908
PCL1
Other alias
HGNC (Hugo) PCYOX1
LocusID (NCBI) 51449
Atlas_Id 71777
Location 2p13.3  [Link to chromosome band 2p13]
Location_base_pair Starts at 70258099 and ends at 70281185 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
PCYOX1 (2p13.3) / CEL (9q34.2)PCYOX1 (2p13.3) / MAST3 (19p13.11)PCYOX1 (2p13.3) / UBAP2 (9p13.3)
SPRR2A (1q21.3) / PCYOX1 (2p13.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PCYOX1   20588
Cards
Entrez_Gene (NCBI)PCYOX1  51449  prenylcysteine oxidase 1
AliasesPCL1
GeneCards (Weizmann)PCYOX1
Ensembl hg19 (Hinxton)ENSG00000116005 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000116005 [Gene_View]  chr2:70258099-70281185 [Contig_View]  PCYOX1 [Vega]
ICGC DataPortalENSG00000116005
TCGA cBioPortalPCYOX1
AceView (NCBI)PCYOX1
Genatlas (Paris)PCYOX1
WikiGenes51449
SOURCE (Princeton)PCYOX1
Genetics Home Reference (NIH)PCYOX1
Genomic and cartography
GoldenPath hg38 (UCSC)PCYOX1  -     chr2:70258099-70281185 +  2p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PCYOX1  -     2p13.3   [Description]    (hg19-Feb_2009)
EnsemblPCYOX1 - 2p13.3 [CytoView hg19]  PCYOX1 - 2p13.3 [CytoView hg38]
Mapping of homologs : NCBIPCYOX1 [Mapview hg19]  PCYOX1 [Mapview hg38]
OMIM610995   
Gene and transcription
Genbank (Entrez)AB020715 AF181490 AK225302 AK296478 AK303043
RefSeq transcript (Entrez)NM_016297
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PCYOX1
Cluster EST : UnigeneHs.567502 [ NCBI ]
CGAP (NCI)Hs.567502
Alternative Splicing GalleryENSG00000116005
Gene ExpressionPCYOX1 [ NCBI-GEO ]   PCYOX1 [ EBI - ARRAY_EXPRESS ]   PCYOX1 [ SEEK ]   PCYOX1 [ MEM ]
Gene Expression Viewer (FireBrowse)PCYOX1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51449
GTEX Portal (Tissue expression)PCYOX1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UHG3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UHG3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UHG3
Splice isoforms : SwissVarQ9UHG3
Catalytic activity : Enzyme1.8.3.5 [ Enzyme-Expasy ]   1.8.3.51.8.3.5 [ IntEnz-EBI ]   1.8.3.5 [ BRENDA ]   1.8.3.5 [ KEGG ]   
PhosPhoSitePlusQ9UHG3
Domains : Interpro (EBI)FAD/NAD-binding_dom    Prenylcys_lyase    Prenylcysteine_Oxase   
Domain families : Pfam (Sanger)Prenylcys_lyase (PF07156)   
Domain families : Pfam (NCBI)pfam07156   
Conserved Domain (NCBI)PCYOX1
DMDM Disease mutations51449
Blocks (Seattle)PCYOX1
SuperfamilyQ9UHG3
Human Protein AtlasENSG00000116005
Peptide AtlasQ9UHG3
HPRD11422
IPIIPI00384280   IPI01010177   IPI00924611   IPI00925564   IPI00927689   IPI00927939   
Protein Interaction databases
DIP (DOE-UCLA)Q9UHG3
IntAct (EBI)Q9UHG3
FunCoupENSG00000116005
BioGRIDPCYOX1
STRING (EMBL)PCYOX1
ZODIACPCYOX1
Ontologies - Pathways
QuickGOQ9UHG3
Ontology : AmiGOprenylcysteine oxidase activity  lysosome  vacuolar membrane  plasma membrane  chloride-transporting ATPase activity  prenylated protein catabolic process  prenylated protein catabolic process  prenylcysteine catabolic process  prenylcysteine metabolic process  very-low-density lipoprotein particle  oxidation-reduction process  extracellular exosome  ATP hydrolysis coupled anion transmembrane transport  chloride transmembrane transport  
Ontology : EGO-EBIprenylcysteine oxidase activity  lysosome  vacuolar membrane  plasma membrane  chloride-transporting ATPase activity  prenylated protein catabolic process  prenylated protein catabolic process  prenylcysteine catabolic process  prenylcysteine metabolic process  very-low-density lipoprotein particle  oxidation-reduction process  extracellular exosome  ATP hydrolysis coupled anion transmembrane transport  chloride transmembrane transport  
Pathways : KEGGTerpenoid backbone biosynthesis   
NDEx NetworkPCYOX1
Atlas of Cancer Signalling NetworkPCYOX1
Wikipedia pathwaysPCYOX1
Orthology - Evolution
OrthoDB51449
GeneTree (enSembl)ENSG00000116005
Phylogenetic Trees/Animal Genes : TreeFamPCYOX1
HOVERGENQ9UHG3
HOGENOMQ9UHG3
Homologs : HomoloGenePCYOX1
Homology/Alignments : Family Browser (UCSC)PCYOX1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPCYOX1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PCYOX1
dbVarPCYOX1
ClinVarPCYOX1
1000_GenomesPCYOX1 
Exome Variant ServerPCYOX1
ExAC (Exome Aggregation Consortium)PCYOX1 (select the gene name)
Genetic variants : HAPMAP51449
Genomic Variants (DGV)PCYOX1 [DGVbeta]
DECIPHERPCYOX1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPCYOX1 
Mutations
ICGC Data PortalPCYOX1 
TCGA Data PortalPCYOX1 
Broad Tumor PortalPCYOX1
OASIS PortalPCYOX1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPCYOX1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPCYOX1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PCYOX1
DgiDB (Drug Gene Interaction Database)PCYOX1
DoCM (Curated mutations)PCYOX1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PCYOX1 (select a term)
intoGenPCYOX1
Cancer3DPCYOX1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610995   
Orphanet
MedgenPCYOX1
Genetic Testing Registry PCYOX1
NextProtQ9UHG3 [Medical]
TSGene51449
GENETestsPCYOX1
Target ValidationPCYOX1
Huge Navigator PCYOX1 [HugePedia]
snp3D : Map Gene to Disease51449
BioCentury BCIQPCYOX1
ClinGenPCYOX1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51449
Chemical/Pharm GKB GenePA134959852
Clinical trialPCYOX1
Miscellaneous
canSAR (ICR)PCYOX1 (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePCYOX1
EVEXPCYOX1
GoPubMedPCYOX1
iHOPPCYOX1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:35:55 CEST 2017

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