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PDC (phosducin)

Identity

Alias_symbol (synonym)MEKA
Other aliasPHD
PhLOP
PhLP
HGNC (Hugo) PDC
LocusID (NCBI) 5132
Atlas_Id 71781
Location 1q31.1  [Link to chromosome band 1q31]
Location_base_pair Starts at 186443566 and ends at 186461108 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
NUP98 (11p15.4) / PDC (1q31.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PDC   8759
Cards
Entrez_Gene (NCBI)PDC  5132  phosducin
AliasesMEKA; PHD; PhLOP; PhLP
GeneCards (Weizmann)PDC
Ensembl hg19 (Hinxton)ENSG00000116703 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000116703 [Gene_View]  chr1:186443566-186461108 [Contig_View]  PDC [Vega]
ICGC DataPortalENSG00000116703
TCGA cBioPortalPDC
AceView (NCBI)PDC
Genatlas (Paris)PDC
WikiGenes5132
SOURCE (Princeton)PDC
Genetics Home Reference (NIH)PDC
Genomic and cartography
GoldenPath hg38 (UCSC)PDC  -     chr1:186443566-186461108 -  1q31.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PDC  -     1q31.1   [Description]    (hg19-Feb_2009)
EnsemblPDC - 1q31.1 [CytoView hg19]  PDC - 1q31.1 [CytoView hg38]
Mapping of homologs : NCBIPDC [Mapview hg19]  PDC [Mapview hg38]
OMIM171490   
Gene and transcription
Genbank (Entrez)AF076464 BC093839 BC112134 BC148616 BC153182
RefSeq transcript (Entrez)NM_002597 NM_022576 NM_022577
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PDC
Cluster EST : UnigeneHs.654381 [ NCBI ]
CGAP (NCI)Hs.654381
Alternative Splicing GalleryENSG00000116703
Gene ExpressionPDC [ NCBI-GEO ]   PDC [ EBI - ARRAY_EXPRESS ]   PDC [ SEEK ]   PDC [ MEM ]
Gene Expression Viewer (FireBrowse)PDC [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5132
GTEX Portal (Tissue expression)PDC
Protein : pattern, domain, 3D structure
UniProt/SwissProtP20941   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP20941  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP20941
Splice isoforms : SwissVarP20941
PhosPhoSitePlusP20941
Domains : Interpro (EBI)Phosducin    Phosducin_N_dom    Phosducin_thioredoxin-like_dom    Thioredoxin-like_fold   
Domain families : Pfam (Sanger)Phosducin (PF02114)   
Domain families : Pfam (NCBI)pfam02114   
Conserved Domain (NCBI)PDC
DMDM Disease mutations5132
Blocks (Seattle)PDC
SuperfamilyP20941
Human Protein AtlasENSG00000116703
Peptide AtlasP20941
HPRD01373
IPIIPI00054502   IPI00021743   IPI00021742   
Protein Interaction databases
DIP (DOE-UCLA)P20941
IntAct (EBI)P20941
FunCoupENSG00000116703
BioGRIDPDC
STRING (EMBL)PDC
ZODIACPDC
Ontologies - Pathways
QuickGOP20941
Ontology : AmiGOphotoreceptor outer segment  photoreceptor inner segment  phospholipase inhibitor activity  nucleus  cytoplasm  cytosol  G-protein coupled receptor signaling pathway  visual perception  phototransduction  queuine tRNA-ribosyltransferase activity  queuosine biosynthetic process  negative regulation of catalytic activity  
Ontology : EGO-EBIphotoreceptor outer segment  photoreceptor inner segment  phospholipase inhibitor activity  nucleus  cytoplasm  cytosol  G-protein coupled receptor signaling pathway  visual perception  phototransduction  queuine tRNA-ribosyltransferase activity  queuosine biosynthetic process  negative regulation of catalytic activity  
Pathways : KEGGOlfactory transduction   
NDEx NetworkPDC
Atlas of Cancer Signalling NetworkPDC
Wikipedia pathwaysPDC
Orthology - Evolution
OrthoDB5132
GeneTree (enSembl)ENSG00000116703
Phylogenetic Trees/Animal Genes : TreeFamPDC
HOVERGENP20941
HOGENOMP20941
Homologs : HomoloGenePDC
Homology/Alignments : Family Browser (UCSC)PDC
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPDC [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PDC
dbVarPDC
ClinVarPDC
1000_GenomesPDC 
Exome Variant ServerPDC
ExAC (Exome Aggregation Consortium)PDC (select the gene name)
Genetic variants : HAPMAP5132
Genomic Variants (DGV)PDC [DGVbeta]
DECIPHERPDC [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPDC 
Mutations
ICGC Data PortalPDC 
TCGA Data PortalPDC 
Broad Tumor PortalPDC
OASIS PortalPDC [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPDC  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPDC
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Eye diseases - LOVD
BioMutasearch PDC
DgiDB (Drug Gene Interaction Database)PDC
DoCM (Curated mutations)PDC (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PDC (select a term)
intoGenPDC
Cancer3DPDC(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM171490   
Orphanet
MedgenPDC
Genetic Testing Registry PDC
NextProtP20941 [Medical]
TSGene5132
GENETestsPDC
Target ValidationPDC
Huge Navigator PDC [HugePedia]
snp3D : Map Gene to Disease5132
BioCentury BCIQPDC
ClinGenPDC
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5132
Chemical/Pharm GKB GenePA33109
Clinical trialPDC
Miscellaneous
canSAR (ICR)PDC (select the gene name)
Probes
Litterature
PubMed32 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePDC
EVEXPDC
GoPubMedPDC
iHOPPDC
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:34:13 CEST 2017

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