Identity
HGNC
LOCATION
11q13.4
LOCUSID
ALIAS
CGS-PDE,IDDPADS,PDE2A1,PED2A4,cGSPDE
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5138
MIM: 602658
HGNC: 8777
Ensembl: ENSG00000186642
Variants:
dbSNP: 5138
ClinVar: 5138
TCGA: ENSG00000186642
COSMIC: PDE2A
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38159569 | 2024 | The phosphodiesterase 2A controls lymphatic junctional maturation via cGMP-dependent notch signaling. | 0 |
| 38159569 | 2024 | The phosphodiesterase 2A controls lymphatic junctional maturation via cGMP-dependent notch signaling. | 0 |
| 36611861 | 2022 | Low Expression of Phosphodiesterase 2 (PDE2A) Promotes the Progression by Regulating Mitochondrial Morphology and ATP Content and Predicts Poor Prognosis in Hepatocellular Carcinoma. | 5 |
| 36611861 | 2022 | Low Expression of Phosphodiesterase 2 (PDE2A) Promotes the Progression by Regulating Mitochondrial Morphology and ATP Content and Predicts Poor Prognosis in Hepatocellular Carcinoma. | 5 |
| 33112806 | 2021 | Phosphodiesterase 2A and 3B variants are associated with primary aldosteronism. | 11 |
| 34512162 | 2021 | miR-139/PDE2A-Notch1 feedback circuit represses stemness of gliomas by inhibiting Wnt/β-catenin signaling. | 14 |
| 33112806 | 2021 | Phosphodiesterase 2A and 3B variants are associated with primary aldosteronism. | 11 |
| 34512162 | 2021 | miR-139/PDE2A-Notch1 feedback circuit represses stemness of gliomas by inhibiting Wnt/β-catenin signaling. | 14 |
| 32119913 | 2020 | Phosphodiesterases PDE2A and PDE10A both change mRNA expression in the human brain with age, but only PDE2A changes in a region-specific manner with psychiatric disease. | 9 |
| 32196122 | 2020 | A Homozygous Splicing Mutation in PDE2A in a Family With Atypical Rett Syndrome. | 3 |
| 32343157 | 2020 | A Novel Inhibition Modality for Phosphodiesterase 2A. | 1 |
| 32467598 | 2020 | Biallelic PDE2A variants: a new cause of syndromic paroxysmal dyskinesia. | 11 |
| 33087821 | 2020 | Phosphodiesterase 2A2 regulates mitochondria clearance through Parkin-dependent mitophagy. | 11 |
| 32119913 | 2020 | Phosphodiesterases PDE2A and PDE10A both change mRNA expression in the human brain with age, but only PDE2A changes in a region-specific manner with psychiatric disease. | 9 |
| 32196122 | 2020 | A Homozygous Splicing Mutation in PDE2A in a Family With Atypical Rett Syndrome. | 3 |
Citation
Dessen P
PDE2A (phosphodiesterase 2A)
Atlas Genet Cytogenet Oncol Haematol. 2011-10-01
Online version: http://atlasgeneticsoncology.org/gene/52455/pde2a
