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PDE4A (phosphodiesterase 4A)

Identity

Alias (NCBI)DPDE2
PDE4
PDE46
HGNC (Hugo) PDE4A
HGNC Alias namephosphodiesterase E2 dunce homolog (Drosophila)
HGNC Previous nameDPDE2
HGNC Previous namephosphodiesterase 4A, cAMP-specific (dunce (Drosophila)-homolog phosphodiesterase E2)
 phosphodiesterase 4A, cAMP-specific
LocusID (NCBI) 5141
Atlas_Id 45808
Location 19p13.2  [Link to chromosome band 19p13]
Location_base_pair Starts at 10452932 and ends at 10469630 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
DNM2 (19p13.2) / PDE4A (19p13.2)GPR108 (19p13.3) / PDE4A (19p13.2)PDE4A (19p13.2) / GPR108 (19p13.3)
PDE4A (19p13.2) / MIPOL1 (14q13.3)PDE4A (19p13.2) / S1PR5 (19p13.2)DNM2 19p13.2 / PDE4A 19p13.2
PDE4A 19p13.2 / S1PR5 19p13.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)PDE4A   8780
Cards
Entrez_Gene (NCBI)PDE4A    phosphodiesterase 4A
AliasesDPDE2; PDE4; PDE46
GeneCards (Weizmann)PDE4A
Ensembl hg19 (Hinxton)ENSG00000065989 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000065989 [Gene_View]  ENSG00000065989 [Sequence]  chr19:10452932-10469630 [Contig_View]  PDE4A [Vega]
ICGC DataPortalENSG00000065989
TCGA cBioPortalPDE4A
AceView (NCBI)PDE4A
Genatlas (Paris)PDE4A
SOURCE (Princeton)PDE4A
Genetics Home Reference (NIH)PDE4A
Genomic and cartography
GoldenPath hg38 (UCSC)PDE4A  -     chr19:10452932-10469630 +  19p13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PDE4A  -     19p13.2   [Description]    (hg19-Feb_2009)
GoldenPathPDE4A - 19p13.2 [CytoView hg19]  PDE4A - 19p13.2 [CytoView hg38]
ImmunoBaseENSG00000065989
genome Data Viewer NCBIPDE4A [Mapview hg19]  
OMIM600126   
Gene and transcription
Genbank (Entrez)AF073745 AW138155 AY266362 AY593872 AY618547
RefSeq transcript (Entrez)NM_001111307 NM_001111308 NM_001111309 NM_001243121 NM_006202
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PDE4A
Alternative Splicing GalleryENSG00000065989
Gene ExpressionPDE4A [ NCBI-GEO ]   PDE4A [ EBI - ARRAY_EXPRESS ]   PDE4A [ SEEK ]   PDE4A [ MEM ]
Gene Expression Viewer (FireBrowse)PDE4A [ Firebrowse - Broad ]
GenevisibleExpression of PDE4A in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5141
GTEX Portal (Tissue expression)PDE4A
Human Protein AtlasENSG00000065989-PDE4A [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)PDE4A
Blocks (Seattle)PDE4A
Human Protein Atlas [tissue]ENSG00000065989-PDE4A [tissue]
HPRD02527
IPIIPI00020973   IPI00220048   IPI00006232   IPI00171460   IPI00220052   IPI00945522   IPI00940499   IPI00002446   IPI00941003   
Protein Interaction databases
BioGRIDPDE4A
STRING (EMBL)PDE4A
ZODIACPDE4A
Ontologies - Pathways
Litterature
PubMed82 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXPDE4A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 25 19:38:41 CET 2021
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