Identity
HGNC
LOCATION
15q15.3
LOCUSID
ALIAS
ER60,ERp57,ERp60,ERp61,GRP57,GRP58,HEL-S-269,HEL-S-93n,HsT17083,P58,PI-PLC
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2923
MIM: 602046
HGNC: 4606
Ensembl: ENSG00000167004
Variants:
dbSNP: 2923
ClinVar: 2923
TCGA: ENSG00000167004
COSMIC: PDIA3
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38412717 | 2024 | Downregulation of PDIA3 inhibits gastric cancer cell growth through cell cycle regulation. | 0 |
| 38412717 | 2024 | Downregulation of PDIA3 inhibits gastric cancer cell growth through cell cycle regulation. | 0 |
| 36374169 | 2023 | Protein disulfide isomerase A3 activity promotes extracellular accumulation of proteins relevant to basal breast cancer outcomes in human MDA-MB-A231 breast cancer cells. | 4 |
| 36769334 | 2023 | PDIA3 Expression Is Altered in the Limbic Brain Regions of Triple-Transgenic Mouse Model of Alzheimer's Disease. | 3 |
| 36889696 | 2023 | Interaction with ERp57 is required for progranulin protection against Type 2 Gaucher disease. | 2 |
| 37549780 | 2023 | PDIA3 modulates genomic response to 1,25-dihydroxyvitamin D(3) in squamous cell carcinoma of the skin. | 4 |
| 36374169 | 2023 | Protein disulfide isomerase A3 activity promotes extracellular accumulation of proteins relevant to basal breast cancer outcomes in human MDA-MB-A231 breast cancer cells. | 4 |
| 36769334 | 2023 | PDIA3 Expression Is Altered in the Limbic Brain Regions of Triple-Transgenic Mouse Model of Alzheimer's Disease. | 3 |
| 36889696 | 2023 | Interaction with ERp57 is required for progranulin protection against Type 2 Gaucher disease. | 2 |
| 37549780 | 2023 | PDIA3 modulates genomic response to 1,25-dihydroxyvitamin D(3) in squamous cell carcinoma of the skin. | 4 |
| 34732604 | 2022 | Correlation between low expression of protein disulfide isomerase A3 and lymph node metastasis in papillary thyroid carcinoma and poor prognosis: a clinicopathological study of 1,139 cases with long-term follow-up. | 4 |
| 34904718 | 2022 | Mutation in protein disulfide isomerase A3 causes neurodevelopmental defects by disturbing endoplasmic reticulum proteostasis. | 10 |
| 34983301 | 2022 | Protein disulfide-isomerase A3 knockdown attenuates oxidized low-density lipoprotein-induced oxidative stress, inflammation and endothelial dysfunction in human umbilical vein endothelial cells by downregulating activating transcription factor 2. | 3 |
| 34996009 | 2022 | The expression of anti-protein disulfide isomerase A3 autoantibody is associated with the increased risk of miscarriage in euthyroid women with thyroid autoimmunity. | 3 |
| 35162999 | 2022 | Protein Disulfide Isomerase A3 Regulates Influenza Neuraminidase Activity and Influenza Burden in the Lung. | 2 |
Citation
Dessen P
PDIA3 (protein disulfide isomerase family A member 3)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46338/pdia3
