PDIA3 (protein disulfide isomerase family A, member 3)

Identity

Other names	ER60
	ERp57
	ERp60
	ERp61
	GRP57
	GRP58
	HsT17083
	P58
	PI-PLC
HGNC	PDIA3
Location	15q15
Location_base_pair	Starts at 41825882 and ends at 41852096 bp from pter (hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	PDIA3   4606
Entrez_Gene	PDIA3  2923  protein disulfide isomerase family A, member 3
	Cards
GeneCards	PDIA3
Ensembl	PDIA3 [Search_View]   ENSG00000167004 [Gene_View]
Genatlas	PDIA3
GeneLynx	PDIA3
eGenome	PDIA3
euGene	2923
	Genomic and cartography
GoldenPath	PDIA3  -  15q15   chr15:41825882-41852096 +  15q15.3   [Description]    (hg18-March_2006)
Ensembl	PDIA3 - 15q15.3 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	PDIA3
	Gene and transcription
Genbank	AI769725 [ ENTREZ ]
Genbank	AK075455 [ ENTREZ ]
Genbank	AK075481 [ ENTREZ ]
Genbank	BC014433 [ ENTREZ ]
Genbank	BC036000 [ ENTREZ ]
RefSeq	NM_005313 [ SRS ]    NM_005313 [ ENTREZ ]
RefSeq	AC_000058 [ SRS ]    AC_000058 [ ENTREZ ]
RefSeq	AC_000147 [ SRS ]    AC_000147 [ ENTREZ ]
RefSeq	NC_000015 [ SRS ]    NC_000015 [ ENTREZ ]
RefSeq	NG_005156 [ SRS ]    NG_005156 [ ENTREZ ]
RefSeq	NT_010194 [ SRS ]    NT_010194 [ ENTREZ ]
RefSeq	NW_001838218 [ SRS ]    NW_001838218 [ ENTREZ ]
RefSeq	NW_925884 [ SRS ]    NW_925884 [ ENTREZ ]
AceView	PDIA3 AceView - NCBI
Unigene	Hs.712781 [ SRS ]    Hs.712781 [ NCBI ]     HS712781 [ spliceNest ]
Fast-db	4060 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P30101 [ SRS]    P30101 [ EXPASY ]     P30101 [ INTERPRO ]     P30101 [ UNIPROT ]
Prosite	PS00194 THIOREDOXIN_1 [ SRS ]    PS00194 THIOREDOXIN_1 [ Expasy ]
Prosite	PS51352 THIOREDOXIN_2 [ SRS ]    PS51352 THIOREDOXIN_2 [ Expasy ]
Interpro	IPR005788 Disulph_isom [ SRS ]    IPR005788 Disulph_isom [ EBI ]
Interpro	IPR005792 Disulphide_isom [ SRS ]    IPR005792 Disulphide_isom [ EBI ]
Interpro	IPR006662 Thioredoxin-like [ SRS ]    IPR006662 Thioredoxin-like [ EBI ]
Interpro	IPR013766 Thioredoxin_dom [ SRS ]    IPR013766 Thioredoxin_dom [ EBI ]
Interpro	IPR012335 Thioredoxin_fold [ SRS ]    IPR012335 Thioredoxin_fold [ EBI ]
CluSTr	P30101
Pfam	PF00085 Thioredoxin [ SRS ]    PF00085 Thioredoxin [ Sanger ]    pfam00085 [ NCBI-CDD ]
Blocks	P30101
PDB	2ALB [ SRS ]    2ALB [ PdbSum ],   2ALB [ IMB ]   2ALB [ RSDB ]
PDB	2DMM [ SRS ]    2DMM [ PdbSum ],   2DMM [ IMB ]   2DMM [ RSDB ]
PDB	2H8L [ SRS ]    2H8L [ PdbSum ],   2H8L [ IMB ]   2H8L [ RSDB ]
HPRD	03625
	Protein Interaction databases
DIP	P30101
IntAct	P30101
	Polymorphism : SNP, mutations, diseases
OMIM	602046    [ map ]
GENECLINICS	602046
SNP	PDIA3 [dbSNP-NCBI]
SNP	NM_005313 [SNP-NCI]
SNP	PDIA3 [GeneSNPs - Utah]  PDIA3] [HGBASE - SRS]
HAPMAP	PDIA3 [HAPMAP]
HGMD	PDIA3
	General knowledge
Family Browser	PDIA3 [UCSC Family Browser]
SOURCE	NM_005313
SMD	Hs.712781
SAGE	Hs.712781
Enzyme	5.3.4.1 [ Enzyme-Expasy ]   5.3.4.1 [ Enzyme-SRS ]   5.3.4.1 [ IntEnz-EBI ]   5.3.4.1 [ BRENDA ]   5.3.4.1 [ KEGG ]   5.3.4.1 [ WIT ]
GO	protein disulfide isomerase activity [Amigo]  protein disulfide isomerase activity
GO	cysteine-type endopeptidase activity [Amigo]  cysteine-type endopeptidase activity
GO	phospholipase C activity [Amigo]  phospholipase C activity
GO	protein binding [Amigo]  protein binding
GO	endoplasmic reticulum [Amigo]  endoplasmic reticulum
GO	endoplasmic reticulum lumen [Amigo]  endoplasmic reticulum lumen
GO	protein import into nucleus [Amigo]  protein import into nucleus
GO	protein retention in ER lumen [Amigo]  protein retention in ER lumen
GO	signal transduction [Amigo]  signal transduction
GO	isomerase activity [Amigo]  isomerase activity
GO	melanosome [Amigo]  melanosome
GO	positive regulation of apoptosis [Amigo]  positive regulation of apoptosis
GO	cell redox homeostasis [Amigo]  cell redox homeostasis
KEGG	Antigen processing and presentation
PubGene	PDIA3
TreeFam	PDIA3
CTD	2923 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	PDIA3 Related clones (RZPD - Berlin)
	PubMed
PubMed	68 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 11 13:25:10 2008