Identity
HGNC
LOCATION
2p25.1
LOCUSID
ALIAS
ERP5,P5,TXNDC7
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10130
MIM: 611099
HGNC: 30168
Ensembl: ENSG00000143870
Variants:
dbSNP: 10130
ClinVar: 10130
TCGA: ENSG00000143870
COSMIC: PDIA6
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38441855 | 2024 | The SOX2/PDIA6 axis mediates aerobic glycolysis to promote stemness in non-small cell lung cancer cells. | 0 |
| 38441855 | 2024 | The SOX2/PDIA6 axis mediates aerobic glycolysis to promote stemness in non-small cell lung cancer cells. | 0 |
| 36244946 | 2023 | Downregulated miR-181a alleviates H(2)O(2)-induced oxidative stress and cellular senescence by targeting PDIA6 in human foreskin fibroblasts. | 1 |
| 38097564 | 2023 | PDIA6, which is regulated by TRPM2-AS/miR-424-5p axis, promotes endometrial cancer progression via TGF-beta pathway. | 0 |
| 36244946 | 2023 | Downregulated miR-181a alleviates H(2)O(2)-induced oxidative stress and cellular senescence by targeting PDIA6 in human foreskin fibroblasts. | 1 |
| 38097564 | 2023 | PDIA6, which is regulated by TRPM2-AS/miR-424-5p axis, promotes endometrial cancer progression via TGF-beta pathway. | 0 |
| 35848924 | 2022 | Melanoma RBPome identification reveals PDIA6 as an unconventional RNA-binding protein involved in metastasis. | 5 |
| 35848924 | 2022 | Melanoma RBPome identification reveals PDIA6 as an unconventional RNA-binding protein involved in metastasis. | 5 |
| 33495992 | 2021 | Biallelic loss of function variant in the unfolded protein response gene PDIA6 is associated with asphyxiating thoracic dystrophy and neonatal-onset diabetes. | 7 |
| 33761940 | 2021 | PDIA6 contributes to aerobic glycolysis and cancer progression in oral squamous cell carcinoma. | 11 |
| 34325342 | 2021 | PDIA6 promotes pancreatic cancer progression and immune escape through CSN5-mediated deubiquitination of β-catenin and PD-L1. | 16 |
| 34781823 | 2021 | Protein disulfide isomerase family 6 promotes the imatinib-resistance of renal cell carcinoma by regulation of Wnt3a-Frizzled1 axis. | 1 |
| 33495992 | 2021 | Biallelic loss of function variant in the unfolded protein response gene PDIA6 is associated with asphyxiating thoracic dystrophy and neonatal-onset diabetes. | 7 |
| 33761940 | 2021 | PDIA6 contributes to aerobic glycolysis and cancer progression in oral squamous cell carcinoma. | 11 |
| 34325342 | 2021 | PDIA6 promotes pancreatic cancer progression and immune escape through CSN5-mediated deubiquitination of β-catenin and PD-L1. | 16 |
Citation
Dessen P
PDIA6 (protein disulfide isomerase family A member 6)
Atlas Genet Cytogenet Oncol Haematol. 2012-10-01
Online version: http://atlasgeneticsoncology.org/gene/52908/pdia6
