PDK3 (pyruvate dehydrogenase kinase, isozyme 3)

Identity

Other names	-
HGNC	PDK3
Location	Xp22.12
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	PDK3   8811
Entrez_Gene	PDK3  5165  pyruvate dehydrogenase kinase, isozyme 3
	Cards
GeneCards	PDK3
Ensembl	PDK3 [Search_View]   ENSG00000067992 [Gene_View]
Genatlas	PDK3
GeneLynx	PDK3
eGenome	PDK3
euGene	5165
	Genomic and cartography
GoldenPath	PDK3  -  Xp22.12   chrX:24393475-24462463 +  Xp22.11   [Description]    (hg18-March_2006)
Ensembl	PDK3 - Xp22.11 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	PDK3
	Gene and transcription
Genbank	AK301965 [ ENTREZ ]
Genbank	BC015948 [ ENTREZ ]
Genbank	CR606226 [ ENTREZ ]
Genbank	CR626205 [ ENTREZ ]
Genbank	L42452 [ ENTREZ ]
RefSeq	NM_005391 [ SRS ]    NM_005391 [ ENTREZ ]
RefSeq	AC_000066 [ SRS ]    AC_000066 [ ENTREZ ]
RefSeq	AC_000155 [ SRS ]    AC_000155 [ ENTREZ ]
RefSeq	NC_000023 [ SRS ]    NC_000023 [ ENTREZ ]
RefSeq	NT_011757 [ SRS ]    NT_011757 [ ENTREZ ]
RefSeq	NW_001842360 [ SRS ]    NW_001842360 [ ENTREZ ]
RefSeq	NW_927700 [ SRS ]    NW_927700 [ ENTREZ ]
AceView	PDK3 AceView - NCBI
Unigene	Hs.658190 [ SRS ]    Hs.658190 [ NCBI ]     HS658190 [ spliceNest ]
Fast-db	4499 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q15120 [ SRS]    Q15120 [ EXPASY ]     Q15120 [ INTERPRO ]     Q15120 [ UNIPROT ]
Prosite	PS50109 HIS_KIN [ SRS ]    PS50109 HIS_KIN [ Expasy ]
Interpro	IPR003594 ATP_bd_ATPase [ SRS ]    IPR003594 ATP_bd_ATPase [ EBI ]
Interpro	IPR004358 Sig_transdc_His_kin-like_C [ SRS ]    IPR004358 Sig_transdc_His_kin-like_C [ EBI ]
Interpro	IPR005467 Sig_transdc_His_kinase_core [ SRS ]    IPR005467 Sig_transdc_His_kinase_core [ EBI ]
CluSTr	Q15120
Pfam	PF02518 HATPase_c [ SRS ]    PF02518 HATPase_c [ Sanger ]    pfam02518 [ NCBI-CDD ]
Smart	SM00387 HATPase_c [EMBL]
Blocks	Q15120
PDB	1Y8N [ SRS ]    1Y8N [ PdbSum ],   1Y8N [ IMB ]   1Y8N [ RSDB ]
PDB	1Y8O [ SRS ]    1Y8O [ PdbSum ],   1Y8O [ IMB ]   1Y8O [ RSDB ]
PDB	1Y8P [ SRS ]    1Y8P [ PdbSum ],   1Y8P [ IMB ]   1Y8P [ RSDB ]
PDB	2PNR [ SRS ]    2PNR [ PdbSum ],   2PNR [ IMB ]   2PNR [ RSDB ]
PDB	2Q8I [ SRS ]    2Q8I [ PdbSum ],   2Q8I [ IMB ]   2Q8I [ RSDB ]
HPRD	03956
	Protein Interaction databases
DIP	Q15120
IntAct	Q15120
	Polymorphism : SNP, mutations, diseases
OMIM	602526    [ map ]
GENECLINICS	602526
SNP	PDK3 [dbSNP-NCBI]
SNP	NM_005391 [SNP-NCI]
SNP	PDK3 [GeneSNPs - Utah]  PDK3] [HGBASE - SRS]
HAPMAP	PDK3 [HAPMAP]
COSMIC	PDK3 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	PDK3
	General knowledge
Family Browser	PDK3 [UCSC Family Browser]
SOURCE	NM_005391
SMD	Hs.658190
SAGE	Hs.658190
Enzyme	2.7.11.2 [ Enzyme-Expasy ]   2.7.11.2 [ Enzyme-SRS ]   2.7.11.2 [ IntEnz-EBI ]   2.7.11.2 [ BRENDA ]   2.7.11.2 [ KEGG ]   2.7.11.2 [ WIT ]
GO	two-component sensor activity [Amigo]  two-component sensor activity
GO	pyruvate dehydrogenase (acetyl-transferring) kinase activity [Amigo]  pyruvate dehydrogenase (acetyl-transferring) kinase activity
GO	ATP binding [Amigo]  ATP binding
GO	mitochondrion [Amigo]  mitochondrion
GO	mitochondrial matrix [Amigo]  mitochondrial matrix
GO	carbohydrate metabolic process [Amigo]  carbohydrate metabolic process
GO	glucose metabolic process [Amigo]  glucose metabolic process
GO	signal transduction [Amigo]  signal transduction
GO	phosphorylation [Amigo]  phosphorylation
GO	peptidyl-histidine phosphorylation [Amigo]  peptidyl-histidine phosphorylation
PubGene	PDK3
TreeFam	PDK3
CTD	5165 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	PDK3 Related clones (RZPD - Berlin)
	PubMed
PubMed	17 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 20:24:12 2008