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PDLIM4 (PDZ and LIM domain 4)

Identity

Alias_symbol (synonym)RIL
Other alias
HGNC (Hugo) PDLIM4
LocusID (NCBI) 8572
Atlas_Id 41685
Location 5q31.1  [Link to chromosome band 5q31]
Location_base_pair Starts at 132257658 and ends at 132273454 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
RAD50 (5q31.1) / PDLIM4 (5q31.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PDLIM4   16501
Cards
Entrez_Gene (NCBI)PDLIM4  8572  PDZ and LIM domain 4
AliasesRIL
GeneCards (Weizmann)PDLIM4
Ensembl hg19 (Hinxton)ENSG00000131435 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000131435 [Gene_View]  chr5:132257658-132273454 [Contig_View]  PDLIM4 [Vega]
ICGC DataPortalENSG00000131435
TCGA cBioPortalPDLIM4
AceView (NCBI)PDLIM4
Genatlas (Paris)PDLIM4
WikiGenes8572
SOURCE (Princeton)PDLIM4
Genetics Home Reference (NIH)PDLIM4
Genomic and cartography
GoldenPath hg38 (UCSC)PDLIM4  -     chr5:132257658-132273454 +  5q31.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PDLIM4  -     5q31.1   [Description]    (hg19-Feb_2009)
EnsemblPDLIM4 - 5q31.1 [CytoView hg19]  PDLIM4 - 5q31.1 [CytoView hg38]
Mapping of homologs : NCBIPDLIM4 [Mapview hg19]  PDLIM4 [Mapview hg38]
OMIM166710   603422   
Gene and transcription
Genbank (Entrez)AF153882 AF154335 AK225407 AK313508 AW590987
RefSeq transcript (Entrez)NM_001131027 NM_003687
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PDLIM4
Cluster EST : UnigeneHs.424312 [ NCBI ]
CGAP (NCI)Hs.424312
Alternative Splicing GalleryENSG00000131435
Gene ExpressionPDLIM4 [ NCBI-GEO ]   PDLIM4 [ EBI - ARRAY_EXPRESS ]   PDLIM4 [ SEEK ]   PDLIM4 [ MEM ]
Gene Expression Viewer (FireBrowse)PDLIM4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8572
GTEX Portal (Tissue expression)PDLIM4
Protein : pattern, domain, 3D structure
UniProt/SwissProtP50479   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP50479  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP50479
Splice isoforms : SwissVarP50479
PhosPhoSitePlusP50479
Domaine pattern : Prosite (Expaxy)LIM_DOMAIN_1 (PS00478)    LIM_DOMAIN_2 (PS50023)    PDZ (PS50106)   
Domains : Interpro (EBI)DUF4749    PDZ    Znf_LIM   
Domain families : Pfam (Sanger)DUF4749 (PF15936)    LIM (PF00412)    PDZ (PF00595)   
Domain families : Pfam (NCBI)pfam15936    pfam00412    pfam00595   
Domain families : Smart (EMBL)LIM (SM00132)  PDZ (SM00228)  
Conserved Domain (NCBI)PDLIM4
DMDM Disease mutations8572
Blocks (Seattle)PDLIM4
PDB (SRS)2EEG    2V1W    4Q2O   
PDB (PDBSum)2EEG    2V1W    4Q2O   
PDB (IMB)2EEG    2V1W    4Q2O   
PDB (RSDB)2EEG    2V1W    4Q2O   
Structural Biology KnowledgeBase2EEG    2V1W    4Q2O   
SCOP (Structural Classification of Proteins)2EEG    2V1W    4Q2O   
CATH (Classification of proteins structures)2EEG    2V1W    4Q2O   
SuperfamilyP50479
Human Protein AtlasENSG00000131435
Peptide AtlasP50479
HPRD04571
IPIIPI00032206   IPI00221296   IPI00879300   
Protein Interaction databases
DIP (DOE-UCLA)P50479
IntAct (EBI)P50479
FunCoupENSG00000131435
BioGRIDPDLIM4
STRING (EMBL)PDLIM4
ZODIACPDLIM4
Ontologies - Pathways
QuickGOP50479
Ontology : AmiGOprotein binding  zinc ion binding  
Ontology : EGO-EBIprotein binding  zinc ion binding  
NDEx NetworkPDLIM4
Atlas of Cancer Signalling NetworkPDLIM4
Wikipedia pathwaysPDLIM4
Orthology - Evolution
OrthoDB8572
GeneTree (enSembl)ENSG00000131435
Phylogenetic Trees/Animal Genes : TreeFamPDLIM4
HOVERGENP50479
HOGENOMP50479
Homologs : HomoloGenePDLIM4
Homology/Alignments : Family Browser (UCSC)PDLIM4
Gene fusions - Rearrangements
Fusion : MitelmanRAD50/PDLIM4 [5q31.1/5q31.1]  [t(5;5)(q31;q31)]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPDLIM4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PDLIM4
dbVarPDLIM4
ClinVarPDLIM4
1000_GenomesPDLIM4 
Exome Variant ServerPDLIM4
ExAC (Exome Aggregation Consortium)PDLIM4 (select the gene name)
Genetic variants : HAPMAP8572
Genomic Variants (DGV)PDLIM4 [DGVbeta]
DECIPHERPDLIM4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPDLIM4 
Mutations
ICGC Data PortalPDLIM4 
TCGA Data PortalPDLIM4 
Broad Tumor PortalPDLIM4
OASIS PortalPDLIM4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPDLIM4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPDLIM4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PDLIM4
DgiDB (Drug Gene Interaction Database)PDLIM4
DoCM (Curated mutations)PDLIM4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PDLIM4 (select a term)
intoGenPDLIM4
Cancer3DPDLIM4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM166710    603422   
Orphanet
MedgenPDLIM4
Genetic Testing Registry PDLIM4
NextProtP50479 [Medical]
TSGene8572
GENETestsPDLIM4
Target ValidationPDLIM4
Huge Navigator PDLIM4 [HugePedia]
snp3D : Map Gene to Disease8572
BioCentury BCIQPDLIM4
ClinGenPDLIM4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8572
Chemical/Pharm GKB GenePA134869796
Clinical trialPDLIM4
Miscellaneous
canSAR (ICR)PDLIM4 (select the gene name)
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePDLIM4
EVEXPDLIM4
GoPubMedPDLIM4
iHOPPDLIM4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:24:18 CEST 2017

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