PDLIM5 (PDZ and LIM domain 5)

2003-05-01  

Identity

HGNC
LOCATION
4q22.3
LOCUSID
ALIAS
ENH,ENH1,L9,LIM
FUSION GENES

Other Information

Locus ID:

NCBI: 10611
MIM: 605904
HGNC: 17468
Ensembl: ENSG00000163110

Variants:

dbSNP: 10611
ClinVar: 10611
TCGA: ENSG00000163110
COSMIC: PDLIM5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000163110ENST00000317968Q96HC4
ENSG00000163110ENST00000318007Q96HC4
ENSG00000163110ENST00000359265Q96HC4
ENSG00000163110ENST00000380180Q96HC4
ENSG00000163110ENST00000437932A0A0A0MSP3
ENSG00000163110ENST00000503974Q96HC4
ENSG00000163110ENST00000504489D6RAA1
ENSG00000163110ENST00000506632H0Y8Y3
ENSG00000163110ENST00000508216Q96HC4
ENSG00000163110ENST00000509357H0Y929
ENSG00000163110ENST00000510099A0A0D9SFR4
ENSG00000163110ENST00000512274D6RGG6
ENSG00000163110ENST00000513341H0YBI4
ENSG00000163110ENST00000514743Q96HC4
ENSG00000163110ENST00000542407Q96HC4
ENSG00000163110ENST00000615540Q96HC4
ENSG00000163110ENST00000627587A0A0D9SFW3

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
Neuronal SystemREACTOMER-HSA-112316
Protein-protein interactions at synapsesREACTOMER-HSA-6794362
Interactions of neurexins and neuroligins at synapsesREACTOMER-HSA-6794361

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
197677532009Identification of seven new prostate cancer susceptibility loci through a genome-wide association study.225
147431832004Molecular characterization of bipolar disorder by comparing gene expression profiles of postmortem brains of major mental disorders.86
205643192010Prostate cancer risk-associated variants reported from genome-wide association studies: meta-analysis and their contribution to genetic Variation.36
165497802006The protein ENH is a cytoplasmic sequestration factor for Id2 in normal and tumor cells from the nervous system.23
208789502011Inherited genetic markers discovered to date are able to identify a significant number of men at considerably elevated risk for prostate cancer.20
160441702005Gene expression and association analyses of LIM (PDLIM5) in bipolar disorder and schizophrenia.17
160441702005Gene expression and association analyses of LIM (PDLIM5) in bipolar disorder and schizophrenia.17
153625662004Expression of HSPF1 and LIM in the lymphoblastoid cells derived from patients with bipolar disorder and schizophrenia.16
165951632006Gene expression and association analysis of LIM (PDLIM5) in major depression.14
162134692006A polymorphism in the PDLIM5 gene associated with gene expression and schizophrenia.13

Citation

Dessen P

PDLIM5 (PDZ and LIM domain 5)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/41157/pdlim5