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PDP2 (pyruvate dehyrogenase phosphatase catalytic subunit 2)

Identity

Alias_symbol (synonym)KIAA1348
PPM2C2
PPM2B
Other aliasPDPC 2
HGNC (Hugo) PDP2
LocusID (NCBI) 57546
Atlas_Id 71806
Location 16q22.1  [Link to chromosome band 16q22]
Location_base_pair Starts at 66880361 and ends at 66891099 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PDP2   30263
LRG (Locus Reference Genomic)LRG_1088
Cards
Entrez_Gene (NCBI)PDP2  57546  pyruvate dehyrogenase phosphatase catalytic subunit 2
AliasesPDPC; PPM2B; PPM2C2
GeneCards (Weizmann)PDP2
Ensembl hg19 (Hinxton)ENSG00000172840 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000172840 [Gene_View]  chr16:66880361-66891099 [Contig_View]  PDP2 [Vega]
ICGC DataPortalENSG00000172840
TCGA cBioPortalPDP2
AceView (NCBI)PDP2
Genatlas (Paris)PDP2
WikiGenes57546
SOURCE (Princeton)PDP2
Genetics Home Reference (NIH)PDP2
Genomic and cartography
GoldenPath hg38 (UCSC)PDP2  -     chr16:66880361-66891099 +  16q22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PDP2  -     16q22.1   [Description]    (hg19-Feb_2009)
EnsemblPDP2 - 16q22.1 [CytoView hg19]  PDP2 - 16q22.1 [CytoView hg38]
Mapping of homologs : NCBIPDP2 [Mapview hg19]  PDP2 [Mapview hg38]
OMIM615499   
Gene and transcription
Genbank (Entrez)AB037769 AK292539 BC028030 BM668681 BU735208
RefSeq transcript (Entrez)NM_001329928 NM_001329929 NM_001329930 NM_001329931 NM_001329932 NM_001329933 NM_001329934 NM_020786
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PDP2
Cluster EST : UnigeneHs.632214 [ NCBI ]
CGAP (NCI)Hs.632214
Alternative Splicing GalleryENSG00000172840
Gene ExpressionPDP2 [ NCBI-GEO ]   PDP2 [ EBI - ARRAY_EXPRESS ]   PDP2 [ SEEK ]   PDP2 [ MEM ]
Gene Expression Viewer (FireBrowse)PDP2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57546
GTEX Portal (Tissue expression)PDP2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9P2J9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9P2J9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9P2J9
Splice isoforms : SwissVarQ9P2J9
Catalytic activity : Enzyme3.1.3.43 [ Enzyme-Expasy ]   3.1.3.433.1.3.43 [ IntEnz-EBI ]   3.1.3.43 [ BRENDA ]   3.1.3.43 [ KEGG ]   
PhosPhoSitePlusQ9P2J9
Domaine pattern : Prosite (Expaxy)PPM_1 (PS01032)    PPM_2 (PS51746)   
Domains : Interpro (EBI)PP2C    PP2C_BS    PPM-type_phosphatase_dom   
Domain families : Pfam (Sanger)PP2C (PF00481)   
Domain families : Pfam (NCBI)pfam00481   
Domain families : Smart (EMBL)PP2Cc (SM00332)  
Conserved Domain (NCBI)PDP2
DMDM Disease mutations57546
Blocks (Seattle)PDP2
SuperfamilyQ9P2J9
Human Protein AtlasENSG00000172840
Peptide AtlasQ9P2J9
HPRD15112
IPIIPI00002251   
Protein Interaction databases
DIP (DOE-UCLA)Q9P2J9
IntAct (EBI)Q9P2J9
FunCoupENSG00000172840
BioGRIDPDP2
STRING (EMBL)PDP2
ZODIACPDP2
Ontologies - Pathways
QuickGOQ9P2J9
Ontology : AmiGOprotein serine/threonine phosphatase activity  [pyruvate dehydrogenase (lipoamide)] phosphatase activity  mitochondrial matrix  protein dephosphorylation  regulation of acetyl-CoA biosynthetic process from pyruvate  metal ion binding  
Ontology : EGO-EBIprotein serine/threonine phosphatase activity  [pyruvate dehydrogenase (lipoamide)] phosphatase activity  mitochondrial matrix  protein dephosphorylation  regulation of acetyl-CoA biosynthetic process from pyruvate  metal ion binding  
NDEx NetworkPDP2
Atlas of Cancer Signalling NetworkPDP2
Wikipedia pathwaysPDP2
Orthology - Evolution
OrthoDB57546
GeneTree (enSembl)ENSG00000172840
Phylogenetic Trees/Animal Genes : TreeFamPDP2
HOVERGENQ9P2J9
HOGENOMQ9P2J9
Homologs : HomoloGenePDP2
Homology/Alignments : Family Browser (UCSC)PDP2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPDP2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PDP2
dbVarPDP2
ClinVarPDP2
1000_GenomesPDP2 
Exome Variant ServerPDP2
ExAC (Exome Aggregation Consortium)PDP2 (select the gene name)
Genetic variants : HAPMAP57546
Genomic Variants (DGV)PDP2 [DGVbeta]
DECIPHERPDP2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPDP2 
Mutations
ICGC Data PortalPDP2 
TCGA Data PortalPDP2 
Broad Tumor PortalPDP2
OASIS PortalPDP2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPDP2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPDP2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch PDP2
DgiDB (Drug Gene Interaction Database)PDP2
DoCM (Curated mutations)PDP2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PDP2 (select a term)
intoGenPDP2
Cancer3DPDP2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615499   
Orphanet
MedgenPDP2
Genetic Testing Registry PDP2
NextProtQ9P2J9 [Medical]
TSGene57546
GENETestsPDP2
Target ValidationPDP2
Huge Navigator PDP2 [HugePedia]
snp3D : Map Gene to Disease57546
BioCentury BCIQPDP2
ClinGenPDP2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57546
Chemical/Pharm GKB GenePA165450460
Clinical trialPDP2
Miscellaneous
canSAR (ICR)PDP2 (select the gene name)
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePDP2
EVEXPDP2
GoPubMedPDP2
iHOPPDP2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:35:59 CEST 2017

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