PDRG1 (p53 and DNA damage regulated 1)

2011-07-01  

Identity

HGNC
LOCATION
20q11.21
LOCUSID
ALIAS
C20orf126,PDRG
FUSION GENES

Other Information

Locus ID:

NCBI: 81572
MIM: 610789
HGNC: 16119
Ensembl: ENSG00000088356

Variants:

dbSNP: 81572
ClinVar: 81572
TCGA: ENSG00000088356
COSMIC: PDRG1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000088356ENST00000202017Q9NUG6
ENSG00000088356ENST00000202017A0A384NKN4

Expression (GTEx)

0
50
100
150

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
194506872009High-resolution mapping of the protein interaction network for the human transcription machinery and affinity purification of RNA polymerase II-associated complexes.42
257069192015MicroRNA-214 suppresses oncogenesis and exerts impact on prognosis by targeting PDRG1 in bladder cancer.24
145620552003Cloning and characterization of a novel gene PDRG that is differentially regulated by p53 and ultraviolet radiation.23
211938422011PDRG1, a novel tumor marker for multiple malignancies that is selectively regulated by genotoxic stress.14
276108242016The PDRG1 is an oncogene in lung cancer cells, promoting radioresistance via the ATM-P53 signaling pathway.6
313835352019PDRG1 gene silencing contributes to inhibit the growth and induce apoptosis of gastric cancer cells.2
318824312019Knockdown of PDRG1 Could Inhibit the Wnt Signaling Pathway in Esophageal Cancer Cells.0

Citation

Dessen P

PDRG1 (p53 and DNA damage regulated 1)

Atlas Genet Cytogenet Oncol Haematol. 2011-07-01

Online version: http://atlasgeneticsoncology.org/gene/52294/pdrg1