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PDS5A (PDS5 cohesin associated factor A)

Identity

Alias_namesPDS5
Alias_symbol (synonym)KIAA0648
PIG54
SCC-112
Other aliasSCC112
HGNC (Hugo) PDS5A
LocusID (NCBI) 23244
Atlas_Id 50272
Location 4p14  [Link to chromosome band 4p14]
Location_base_pair Starts at 39822863 and ends at 39977956 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
EIF3E (8q23.1) / PDS5A (4p14)KMT2A (11q23.3) / PDS5A (4p14)PDS5A (4p14) / ABLIM1 (10q25.3)
PDS5A (4p14) / PDS5A (4p14)PDS5A (4p14) / RBM47 (4p14)PLAC8 (4q21.22) / PDS5A (4p14)
UBE2K (4p14) / PDS5A (4p14)KMT2A 11q23.3 / PDS5A 4p14PDS5A 4p14 / RBM47 4p14

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PDS5A   29088
Cards
Entrez_Gene (NCBI)PDS5A  23244  PDS5 cohesin associated factor A
AliasesPIG54; SCC-112; SCC112
GeneCards (Weizmann)PDS5A
Ensembl hg19 (Hinxton)ENSG00000121892 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000121892 [Gene_View]  chr4:39822863-39977956 [Contig_View]  PDS5A [Vega]
ICGC DataPortalENSG00000121892
TCGA cBioPortalPDS5A
AceView (NCBI)PDS5A
Genatlas (Paris)PDS5A
WikiGenes23244
SOURCE (Princeton)PDS5A
Genetics Home Reference (NIH)PDS5A
Genomic and cartography
GoldenPath hg38 (UCSC)PDS5A  -     chr4:39822863-39977956 -  4p14   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PDS5A  -     4p14   [Description]    (hg19-Feb_2009)
EnsemblPDS5A - 4p14 [CytoView hg19]  PDS5A - 4p14 [CytoView hg38]
Mapping of homologs : NCBIPDS5A [Mapview hg19]  PDS5A [Mapview hg38]
OMIM613200   
Gene and transcription
Genbank (Entrez)AB014548 AB621803 AF294791 AK001828 AK021757
RefSeq transcript (Entrez)NM_001100399 NM_001100400 NM_015200
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PDS5A
Cluster EST : UnigeneHs.331431 [ NCBI ]
CGAP (NCI)Hs.331431
Alternative Splicing GalleryENSG00000121892
Gene ExpressionPDS5A [ NCBI-GEO ]   PDS5A [ EBI - ARRAY_EXPRESS ]   PDS5A [ SEEK ]   PDS5A [ MEM ]
Gene Expression Viewer (FireBrowse)PDS5A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23244
GTEX Portal (Tissue expression)PDS5A
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ29RF7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ29RF7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ29RF7
Splice isoforms : SwissVarQ29RF7
PhosPhoSitePlusQ29RF7
Domains : Interpro (EBI)ARM-like    ARM-type_fold   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)PDS5A
DMDM Disease mutations23244
Blocks (Seattle)PDS5A
SuperfamilyQ29RF7
Human Protein AtlasENSG00000121892
Peptide AtlasQ29RF7
HPRD11537
IPIIPI00854642   IPI00854687   IPI00966826   IPI00967084   IPI00966523   
Protein Interaction databases
DIP (DOE-UCLA)Q29RF7
IntAct (EBI)Q29RF7
FunCoupENSG00000121892
BioGRIDPDS5A
STRING (EMBL)PDS5A
ZODIACPDS5A
Ontologies - Pathways
QuickGOQ29RF7
Ontology : AmiGOchromosome, centromeric region  chromatin  protein binding  nucleus  nucleoplasm  nucleoplasm  chromosome  cytosol  plasma membrane  DNA repair  sister chromatid cohesion  mitotic sister chromatid cohesion  negative regulation of DNA replication  cell division  
Ontology : EGO-EBIchromosome, centromeric region  chromatin  protein binding  nucleus  nucleoplasm  nucleoplasm  chromosome  cytosol  plasma membrane  DNA repair  sister chromatid cohesion  mitotic sister chromatid cohesion  negative regulation of DNA replication  cell division  
NDEx NetworkPDS5A
Atlas of Cancer Signalling NetworkPDS5A
Wikipedia pathwaysPDS5A
Orthology - Evolution
OrthoDB23244
GeneTree (enSembl)ENSG00000121892
Phylogenetic Trees/Animal Genes : TreeFamPDS5A
HOVERGENQ29RF7
HOGENOMQ29RF7
Homologs : HomoloGenePDS5A
Homology/Alignments : Family Browser (UCSC)PDS5A
Gene fusions - Rearrangements
Fusion: TCGAPDS5A 4p14 RBM47 4p14 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPDS5A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PDS5A
dbVarPDS5A
ClinVarPDS5A
1000_GenomesPDS5A 
Exome Variant ServerPDS5A
ExAC (Exome Aggregation Consortium)PDS5A (select the gene name)
Genetic variants : HAPMAP23244
Genomic Variants (DGV)PDS5A [DGVbeta]
DECIPHERPDS5A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPDS5A 
Mutations
ICGC Data PortalPDS5A 
TCGA Data PortalPDS5A 
Broad Tumor PortalPDS5A
OASIS PortalPDS5A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPDS5A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPDS5A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
BioMutasearch PDS5A
DgiDB (Drug Gene Interaction Database)PDS5A
DoCM (Curated mutations)PDS5A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PDS5A (select a term)
intoGenPDS5A
Cancer3DPDS5A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613200   
Orphanet
MedgenPDS5A
Genetic Testing Registry PDS5A
NextProtQ29RF7 [Medical]
TSGene23244
GENETestsPDS5A
Target ValidationPDS5A
Huge Navigator PDS5A [HugePedia]
snp3D : Map Gene to Disease23244
BioCentury BCIQPDS5A
ClinGenPDS5A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23244
Chemical/Pharm GKB GenePA162399027
Clinical trialPDS5A
Miscellaneous
canSAR (ICR)PDS5A (select the gene name)
Probes
Litterature
PubMed47 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePDS5A
EVEXPDS5A
GoPubMedPDS5A
iHOPPDS5A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:49:01 CEST 2017

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