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PDSS1 (decaprenyl diphosphate synthase subunit 1)

Identity

Alias (NCBI)COQ1
COQ10D2
COQ1A
DPS
SPS
TPRT
TPT
TPT 1
hDPS1
HGNC (Hugo) PDSS1
HGNC Alias symbTPT
COQ1
HGNC Alias namecoenzyme Q1 homolog (yeast)
HGNC Previous nameTPRT
HGNC Previous nametrans-prenyltransferase
LocusID (NCBI) 23590
Atlas_Id 71808
Location 10p12.1  [Link to chromosome band 10p12]
Location_base_pair Starts at 26697701 and ends at 26746797 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
GCLC (6p12.1) / PDSS1 (10p12.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)PDSS1   17759
Cards
Entrez_Gene (NCBI)PDSS1    decaprenyl diphosphate synthase subunit 1
AliasesCOQ1; COQ10D2; COQ1A; DPS; 
SPS; TPRT; TPT; TPT; hDPS1
GeneCards (Weizmann)PDSS1
Ensembl hg19 (Hinxton)ENSG00000148459 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000148459 [Gene_View]  ENSG00000148459 [Sequence]  chr10:26697701-26746797 [Contig_View]  PDSS1 [Vega]
ICGC DataPortalENSG00000148459
TCGA cBioPortalPDSS1
AceView (NCBI)PDSS1
Genatlas (Paris)PDSS1
SOURCE (Princeton)PDSS1
Genetics Home Reference (NIH)PDSS1
Genomic and cartography
GoldenPath hg38 (UCSC)PDSS1  -     chr10:26697701-26746797 +  10p12.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PDSS1  -     10p12.1   [Description]    (hg19-Feb_2009)
GoldenPathPDSS1 - 10p12.1 [CytoView hg19]  PDSS1 - 10p12.1 [CytoView hg38]
ImmunoBaseENSG00000148459
Genome Data Viewer NCBIPDSS1 [Mapview hg19]  
OMIM607429   614651   
Gene and transcription
Genbank (Entrez)AB209763 AB210838 AF118395 AK024802 AK223414
RefSeq transcript (Entrez)NM_001321978 NM_001321979 NM_014317
Consensus coding sequences : CCDS (NCBI)PDSS1
Gene ExpressionPDSS1 [ NCBI-GEO ]   PDSS1 [ EBI - ARRAY_EXPRESS ]   PDSS1 [ SEEK ]   PDSS1 [ MEM ]
Gene Expression Viewer (FireBrowse)PDSS1 [ Firebrowse - Broad ]
GenevisibleExpression of PDSS1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23590
GTEX Portal (Tissue expression)PDSS1
Human Protein AtlasENSG00000148459-PDSS1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5T2R2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5T2R2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5T2R2
PhosPhoSitePlusQ5T2R2
Domaine pattern : Prosite (Expaxy)POLYPRENYL_SYNTHASE_1 (PS00723)    POLYPRENYL_SYNTHASE_2 (PS00444)   
Domains : Interpro (EBI)Isoprenoid_synthase_dom_sf    Polyprenyl_synt    Polyprenyl_synt_CS   
Domain families : Pfam (Sanger)polyprenyl_synt (PF00348)   
Domain families : Pfam (NCBI)pfam00348   
Conserved Domain (NCBI)PDSS1
SuperfamilyQ5T2R2
AlphaFold pdb e-kbQ5T2R2   
Human Protein Atlas [tissue]ENSG00000148459-PDSS1 [tissue]
HPRD09591
Protein Interaction databases
DIP (DOE-UCLA)Q5T2R2
IntAct (EBI)Q5T2R2
BioGRIDPDSS1
STRING (EMBL)PDSS1
ZODIACPDSS1
Ontologies - Pathways
QuickGOQ5T2R2
Ontology : AmiGOtrans-hexaprenyltranstransferase activity  prenyltransferase activity  protein binding  mitochondrial matrix  ubiquinone biosynthetic process  ubiquinone biosynthetic process  ubiquinone biosynthetic process  ubiquinone biosynthetic process  isoprenoid biosynthetic process  isoprenoid biosynthetic process  metal ion binding  protein heterodimerization activity  trans-octaprenyltranstransferase activity  all-trans-decaprenyl-diphosphate synthase activity  transferase complex  transferase complex  
Ontology : EGO-EBItrans-hexaprenyltranstransferase activity  prenyltransferase activity  protein binding  mitochondrial matrix  ubiquinone biosynthetic process  ubiquinone biosynthetic process  ubiquinone biosynthetic process  ubiquinone biosynthetic process  isoprenoid biosynthetic process  isoprenoid biosynthetic process  metal ion binding  protein heterodimerization activity  trans-octaprenyltranstransferase activity  all-trans-decaprenyl-diphosphate synthase activity  transferase complex  transferase complex  
NDEx NetworkPDSS1
Atlas of Cancer Signalling NetworkPDSS1
Wikipedia pathwaysPDSS1
Orthology - Evolution
OrthoDB23590
GeneTree (enSembl)ENSG00000148459
Phylogenetic Trees/Animal Genes : TreeFamPDSS1
Homologs : HomoloGenePDSS1
Homology/Alignments : Family Browser (UCSC)PDSS1
Gene fusions - Rearrangements
Fusion : QuiverPDSS1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPDSS1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PDSS1
dbVarPDSS1
ClinVarPDSS1
MonarchPDSS1
1000_GenomesPDSS1 
Exome Variant ServerPDSS1
GNOMAD BrowserENSG00000148459
Varsome BrowserPDSS1
ACMGPDSS1 variants
VarityQ5T2R2
Genomic Variants (DGV)PDSS1 [DGVbeta]
DECIPHERPDSS1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPDSS1 
Mutations
ICGC Data PortalPDSS1 
TCGA Data PortalPDSS1 
Broad Tumor PortalPDSS1
OASIS PortalPDSS1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPDSS1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DPDSS1
Mutations and Diseases : HGMDPDSS1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaPDSS1
DgiDB (Drug Gene Interaction Database)PDSS1
DoCM (Curated mutations)PDSS1
CIViC (Clinical Interpretations of Variants in Cancer)PDSS1
Cancer3DPDSS1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607429    614651   
Orphanet19797   
DisGeNETPDSS1
MedgenPDSS1
Genetic Testing Registry PDSS1
NextProtQ5T2R2 [Medical]
GENETestsPDSS1
Target ValidationPDSS1
Huge Navigator PDSS1 [HugePedia]
ClinGenPDSS1
Clinical trials, drugs, therapy
MyCancerGenomePDSS1
Protein Interactions : CTDPDSS1
Pharm GKB GenePA134982512
PharosQ5T2R2
Clinical trialPDSS1
Miscellaneous
canSAR (ICR)PDSS1
HarmonizomePDSS1
DataMed IndexPDSS1
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXPDSS1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 16:15:50 CEST 2021

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