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PDSS1 (decaprenyl diphosphate synthase subunit 1)

Identity

Alias_namesTPRT
trans-prenyltransferase
Alias_symbol (synonym)TPT
COQ1
Other aliasCOQ10D2
DPS
SPS
TPT 1
hDPS1
HGNC (Hugo) PDSS1
LocusID (NCBI) 23590
Atlas_Id 71808
Location 10p12.1  [Link to chromosome band 10p12]
Location_base_pair Starts at 26697424 and ends at 26746797 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
GCLC (6p12.1) / PDSS1 (10p12.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PDSS1   17759
Cards
Entrez_Gene (NCBI)PDSS1  23590  decaprenyl diphosphate synthase subunit 1
AliasesCOQ1; COQ10D2; DPS; SPS; 
TPRT; TPT; TPT; hDPS1
GeneCards (Weizmann)PDSS1
Ensembl hg19 (Hinxton)ENSG00000148459 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000148459 [Gene_View]  chr10:26697424-26746797 [Contig_View]  PDSS1 [Vega]
ICGC DataPortalENSG00000148459
TCGA cBioPortalPDSS1
AceView (NCBI)PDSS1
Genatlas (Paris)PDSS1
WikiGenes23590
SOURCE (Princeton)PDSS1
Genetics Home Reference (NIH)PDSS1
Genomic and cartography
GoldenPath hg38 (UCSC)PDSS1  -     chr10:26697424-26746797 +  10p12.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PDSS1  -     10p12.1   [Description]    (hg19-Feb_2009)
EnsemblPDSS1 - 10p12.1 [CytoView hg19]  PDSS1 - 10p12.1 [CytoView hg38]
Mapping of homologs : NCBIPDSS1 [Mapview hg19]  PDSS1 [Mapview hg38]
OMIM607429   614651   
Gene and transcription
Genbank (Entrez)AB209763 AB210838 AF118395 AK024802 AK223414
RefSeq transcript (Entrez)NM_001321978 NM_001321979 NM_014317
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PDSS1
Cluster EST : UnigeneHs.558468 [ NCBI ]
CGAP (NCI)Hs.558468
Alternative Splicing GalleryENSG00000148459
Gene ExpressionPDSS1 [ NCBI-GEO ]   PDSS1 [ EBI - ARRAY_EXPRESS ]   PDSS1 [ SEEK ]   PDSS1 [ MEM ]
Gene Expression Viewer (FireBrowse)PDSS1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23590
GTEX Portal (Tissue expression)PDSS1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5T2R2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5T2R2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5T2R2
Splice isoforms : SwissVarQ5T2R2
Catalytic activity : Enzyme2.5.1.91 [ Enzyme-Expasy ]   2.5.1.912.5.1.91 [ IntEnz-EBI ]   2.5.1.91 [ BRENDA ]   2.5.1.91 [ KEGG ]   
PhosPhoSitePlusQ5T2R2
Domaine pattern : Prosite (Expaxy)POLYPRENYL_SYNTHASE_1 (PS00723)    POLYPRENYL_SYNTHASE_2 (PS00444)   
Domains : Interpro (EBI)Isoprenoid_synthase_dom    Polyprenyl_synt    Polyprenyl_synt_CS   
Domain families : Pfam (Sanger)polyprenyl_synt (PF00348)   
Domain families : Pfam (NCBI)pfam00348   
Conserved Domain (NCBI)PDSS1
DMDM Disease mutations23590
Blocks (Seattle)PDSS1
SuperfamilyQ5T2R2
Human Protein AtlasENSG00000148459
Peptide AtlasQ5T2R2
HPRD09591
IPIIPI00456157   IPI00440542   IPI00719538   IPI00908300   IPI00871271   IPI00556656   IPI00982039   
Protein Interaction databases
DIP (DOE-UCLA)Q5T2R2
IntAct (EBI)Q5T2R2
FunCoupENSG00000148459
BioGRIDPDSS1
STRING (EMBL)PDSS1
ZODIACPDSS1
Ontologies - Pathways
QuickGOQ5T2R2
Ontology : AmiGOtrans-hexaprenyltranstransferase activity  mitochondrial matrix  ubiquinone biosynthetic process  ubiquinone biosynthetic process  ubiquinone biosynthetic process  isoprenoid biosynthetic process  metal ion binding  protein heterodimerization activity  trans-octaprenyltranstransferase activity  protein heterotetramerization  transferase complex  
Ontology : EGO-EBItrans-hexaprenyltranstransferase activity  mitochondrial matrix  ubiquinone biosynthetic process  ubiquinone biosynthetic process  ubiquinone biosynthetic process  isoprenoid biosynthetic process  metal ion binding  protein heterodimerization activity  trans-octaprenyltranstransferase activity  protein heterotetramerization  transferase complex  
Pathways : KEGGTerpenoid backbone biosynthesis   
NDEx NetworkPDSS1
Atlas of Cancer Signalling NetworkPDSS1
Wikipedia pathwaysPDSS1
Orthology - Evolution
OrthoDB23590
GeneTree (enSembl)ENSG00000148459
Phylogenetic Trees/Animal Genes : TreeFamPDSS1
HOVERGENQ5T2R2
HOGENOMQ5T2R2
Homologs : HomoloGenePDSS1
Homology/Alignments : Family Browser (UCSC)PDSS1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPDSS1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PDSS1
dbVarPDSS1
ClinVarPDSS1
1000_GenomesPDSS1 
Exome Variant ServerPDSS1
ExAC (Exome Aggregation Consortium)PDSS1 (select the gene name)
Genetic variants : HAPMAP23590
Genomic Variants (DGV)PDSS1 [DGVbeta]
DECIPHERPDSS1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPDSS1 
Mutations
ICGC Data PortalPDSS1 
TCGA Data PortalPDSS1 
Broad Tumor PortalPDSS1
OASIS PortalPDSS1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPDSS1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPDSS1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch PDSS1
DgiDB (Drug Gene Interaction Database)PDSS1
DoCM (Curated mutations)PDSS1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PDSS1 (select a term)
intoGenPDSS1
Cancer3DPDSS1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607429    614651   
Orphanet19797   
MedgenPDSS1
Genetic Testing Registry PDSS1
NextProtQ5T2R2 [Medical]
TSGene23590
GENETestsPDSS1
Target ValidationPDSS1
Huge Navigator PDSS1 [HugePedia]
snp3D : Map Gene to Disease23590
BioCentury BCIQPDSS1
ClinGenPDSS1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23590
Chemical/Pharm GKB GenePA134982512
Clinical trialPDSS1
Miscellaneous
canSAR (ICR)PDSS1 (select the gene name)
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePDSS1
EVEXPDSS1
GoPubMedPDSS1
iHOPPDSS1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:36:00 CEST 2017

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