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PDXP (pyridoxal phosphatase)

Identity

Alias_namespyridoxal (pyridoxine
Alias_symbol (synonym)dJ37E16.5
FLJ32703
CIN
Other aliasPLP
HGNC (Hugo) PDXP
LocusID (NCBI) 57026
Atlas_Id 56303
Location 22q13.1  [Link to chromosome band 22q13]
Location_base_pair Starts at 37658730 and ends at 37666932 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PDXP   30259
Cards
Entrez_Gene (NCBI)PDXP  57026  pyridoxal phosphatase
AliasesCIN; PLP; dJ37E16.5
GeneCards (Weizmann)PDXP
Ensembl hg19 (Hinxton)ENSG00000241360 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000241360 [Gene_View]  ENSG00000241360 [Sequence]  chr22:37658730-37666932 [Contig_View]  PDXP [Vega]
ICGC DataPortalENSG00000241360
TCGA cBioPortalPDXP
AceView (NCBI)PDXP
Genatlas (Paris)PDXP
WikiGenes57026
SOURCE (Princeton)PDXP
Genetics Home Reference (NIH)PDXP
Genomic and cartography
GoldenPath hg38 (UCSC)PDXP  -     chr22:37658730-37666932 +  22q13.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PDXP  -     22q13.1   [Description]    (hg19-Feb_2009)
EnsemblPDXP - 22q13.1 [CytoView hg19]  PDXP - 22q13.1 [CytoView hg38]
Mapping of homologs : NCBIPDXP [Mapview hg19]  PDXP [Mapview hg38]
OMIM609246   
Gene and transcription
Genbank (Entrez)AK057265 AY125047 BC000320 BC009756 BC012832
RefSeq transcript (Entrez)NM_020315
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PDXP
Cluster EST : UnigeneHs.632762 [ NCBI ]
CGAP (NCI)Hs.632762
Alternative Splicing GalleryENSG00000241360
Gene ExpressionPDXP [ NCBI-GEO ]   PDXP [ EBI - ARRAY_EXPRESS ]   PDXP [ SEEK ]   PDXP [ MEM ]
Gene Expression Viewer (FireBrowse)PDXP [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57026
GTEX Portal (Tissue expression)PDXP
Human Protein AtlasENSG00000241360-PDXP [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96GD0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96GD0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96GD0
Splice isoforms : SwissVarQ96GD0
PhosPhoSitePlusQ96GD0
Domains : Interpro (EBI)HAD-like_sf    HAD-SF_hydro_IIA    HAD_sf    PGP_euk   
Domain families : Pfam (Sanger)Hydrolase_6 (PF13344)   
Domain families : Pfam (NCBI)pfam13344   
Conserved Domain (NCBI)PDXP
DMDM Disease mutations57026
Blocks (Seattle)PDXP
PDB (SRS)2CFR    2CFS    2CFT    2OYC    2P27    2P69    5GYN   
PDB (PDBSum)2CFR    2CFS    2CFT    2OYC    2P27    2P69    5GYN   
PDB (IMB)2CFR    2CFS    2CFT    2OYC    2P27    2P69    5GYN   
PDB (RSDB)2CFR    2CFS    2CFT    2OYC    2P27    2P69    5GYN   
Structural Biology KnowledgeBase2CFR    2CFS    2CFT    2OYC    2P27    2P69    5GYN   
SCOP (Structural Classification of Proteins)2CFR    2CFS    2CFT    2OYC    2P27    2P69    5GYN   
CATH (Classification of proteins structures)2CFR    2CFS    2CFT    2OYC    2P27    2P69    5GYN   
SuperfamilyQ96GD0
Human Protein Atlas [tissue]ENSG00000241360-PDXP [tissue]
Peptide AtlasQ96GD0
IPIIPI00025340   IPI00941410   
Protein Interaction databases
DIP (DOE-UCLA)Q96GD0
IntAct (EBI)Q96GD0
FunCoupENSG00000241360
BioGRIDPDXP
STRING (EMBL)PDXP
ZODIACPDXP
Ontologies - Pathways
QuickGOQ96GD0
Ontology : AmiGOmagnesium ion binding  phosphoserine phosphatase activity  phosphoprotein phosphatase activity  protein binding  cytoplasm  cytosol  plasma membrane  cell-cell junction  protein dephosphorylation  regulation of mitotic nuclear division  actin cytoskeleton  dephosphorylation  phosphatase activity  lamellipodium  midbody  positive regulation of actin filament depolymerization  heat shock protein binding  actin rod assembly  actin rod assembly  lamellipodium membrane  cleavage furrow  pyridoxal phosphate catabolic process  regulation of cytokinesis  ruffle membrane  pyridoxal phosphatase activity  pyridoxal phosphatase activity  protein homodimerization activity  contractile ring  cellular response to ATP  
Ontology : EGO-EBImagnesium ion binding  phosphoserine phosphatase activity  phosphoprotein phosphatase activity  protein binding  cytoplasm  cytosol  plasma membrane  cell-cell junction  protein dephosphorylation  regulation of mitotic nuclear division  actin cytoskeleton  dephosphorylation  phosphatase activity  lamellipodium  midbody  positive regulation of actin filament depolymerization  heat shock protein binding  actin rod assembly  actin rod assembly  lamellipodium membrane  cleavage furrow  pyridoxal phosphate catabolic process  regulation of cytokinesis  ruffle membrane  pyridoxal phosphatase activity  pyridoxal phosphatase activity  protein homodimerization activity  contractile ring  cellular response to ATP  
Pathways : KEGGVitamin B6 metabolism   
NDEx NetworkPDXP
Atlas of Cancer Signalling NetworkPDXP
Wikipedia pathwaysPDXP
Orthology - Evolution
OrthoDB57026
GeneTree (enSembl)ENSG00000241360
Phylogenetic Trees/Animal Genes : TreeFamPDXP
HOVERGENQ96GD0
HOGENOMQ96GD0
Homologs : HomoloGenePDXP
Homology/Alignments : Family Browser (UCSC)PDXP
Gene fusions - Rearrangements
Fusion : QuiverPDXP
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPDXP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PDXP
dbVarPDXP
ClinVarPDXP
1000_GenomesPDXP 
Exome Variant ServerPDXP
ExAC (Exome Aggregation Consortium)ENSG00000241360
GNOMAD BrowserENSG00000241360
Varsome BrowserPDXP
Genetic variants : HAPMAP57026
Genomic Variants (DGV)PDXP [DGVbeta]
DECIPHERPDXP [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPDXP 
Mutations
ICGC Data PortalPDXP 
TCGA Data PortalPDXP 
Broad Tumor PortalPDXP
OASIS PortalPDXP [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPDXP  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPDXP
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PDXP
DgiDB (Drug Gene Interaction Database)PDXP
DoCM (Curated mutations)PDXP (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PDXP (select a term)
intoGenPDXP
Cancer3DPDXP(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609246   
Orphanet
DisGeNETPDXP
MedgenPDXP
Genetic Testing Registry PDXP
NextProtQ96GD0 [Medical]
TSGene57026
GENETestsPDXP
Target ValidationPDXP
Huge Navigator PDXP [HugePedia]
snp3D : Map Gene to Disease57026
BioCentury BCIQPDXP
ClinGenPDXP
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57026
Chemical/Pharm GKB GenePA134882132
Clinical trialPDXP
Miscellaneous
canSAR (ICR)PDXP (select the gene name)
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePDXP
EVEXPDXP
GoPubMedPDXP
iHOPPDXP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Tue Nov 6 11:29:21 CET 2018

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