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PDZD3 (PDZ domain containing 3)

Identity

Alias_namesPDZK2
PDZ domain containing 2
Alias_symbol (synonym)FLJ22756
IKEPP
Other aliasNHERF4
HGNC (Hugo) PDZD3
LocusID (NCBI) 79849
Atlas_Id 71815
Location 11q23.3  [Link to chromosome band 11q23]
Location_base_pair Starts at 119185457 and ends at 119190223 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PDZD3   19891
Cards
Entrez_Gene (NCBI)PDZD3  79849  PDZ domain containing 3
AliasesIKEPP; NHERF4; PDZK2
GeneCards (Weizmann)PDZD3
Ensembl hg19 (Hinxton)ENSG00000172367 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000172367 [Gene_View]  chr11:119185457-119190223 [Contig_View]  PDZD3 [Vega]
ICGC DataPortalENSG00000172367
TCGA cBioPortalPDZD3
AceView (NCBI)PDZD3
Genatlas (Paris)PDZD3
WikiGenes79849
SOURCE (Princeton)PDZD3
Genetics Home Reference (NIH)PDZD3
Genomic and cartography
GoldenPath hg38 (UCSC)PDZD3  -     chr11:119185457-119190223 +  11q23.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PDZD3  -     11q23.3   [Description]    (hg19-Feb_2009)
EnsemblPDZD3 - 11q23.3 [CytoView hg19]  PDZD3 - 11q23.3 [CytoView hg38]
Mapping of homologs : NCBIPDZD3 [Mapview hg19]  PDZD3 [Mapview hg38]
OMIM607146   
Gene and transcription
Genbank (Entrez)AB094096 AK026409 AK091966 AK298333 AK315403
RefSeq transcript (Entrez)NM_001168468 NM_024791
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PDZD3
Cluster EST : UnigeneHs.374726 [ NCBI ]
CGAP (NCI)Hs.374726
Alternative Splicing GalleryENSG00000172367
Gene ExpressionPDZD3 [ NCBI-GEO ]   PDZD3 [ EBI - ARRAY_EXPRESS ]   PDZD3 [ SEEK ]   PDZD3 [ MEM ]
Gene Expression Viewer (FireBrowse)PDZD3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79849
GTEX Portal (Tissue expression)PDZD3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86UT5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86UT5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86UT5
Splice isoforms : SwissVarQ86UT5
PhosPhoSitePlusQ86UT5
Domaine pattern : Prosite (Expaxy)PDZ (PS50106)   
Domains : Interpro (EBI)NHERF-4    PDZ   
Domain families : Pfam (Sanger)PDZ (PF00595)   
Domain families : Pfam (NCBI)pfam00595   
Domain families : Smart (EMBL)PDZ (SM00228)  
Conserved Domain (NCBI)PDZD3
DMDM Disease mutations79849
Blocks (Seattle)PDZD3
PDB (SRS)2V90   
PDB (PDBSum)2V90   
PDB (IMB)2V90   
PDB (RSDB)2V90   
Structural Biology KnowledgeBase2V90   
SCOP (Structural Classification of Proteins)2V90   
CATH (Classification of proteins structures)2V90   
SuperfamilyQ86UT5
Human Protein AtlasENSG00000172367
Peptide AtlasQ86UT5
HPRD06191
IPIIPI00384252   IPI00171635   IPI00478167   IPI00641673   IPI00646546   IPI01012352   IPI00983196   IPI00983809   
Protein Interaction databases
DIP (DOE-UCLA)Q86UT5
IntAct (EBI)Q86UT5
FunCoupENSG00000172367
BioGRIDPDZD3
STRING (EMBL)PDZD3
ZODIACPDZD3
Ontologies - Pathways
QuickGOQ86UT5
Ontology : AmiGOprotein binding  cytosol  brush border  ion transport  water transport  receptor guanylyl cyclase signaling pathway  protein C-terminus binding  ion channel inhibitor activity  response to toxic substance  cGMP-mediated signaling  guanylate cyclase inhibitor activity  negative regulation of cGMP biosynthetic process  negative regulation of guanylate cyclase activity  subapical complex  apical part of cell  
Ontology : EGO-EBIprotein binding  cytosol  brush border  ion transport  water transport  receptor guanylyl cyclase signaling pathway  protein C-terminus binding  ion channel inhibitor activity  response to toxic substance  cGMP-mediated signaling  guanylate cyclase inhibitor activity  negative regulation of cGMP biosynthetic process  negative regulation of guanylate cyclase activity  subapical complex  apical part of cell  
NDEx NetworkPDZD3
Atlas of Cancer Signalling NetworkPDZD3
Wikipedia pathwaysPDZD3
Orthology - Evolution
OrthoDB79849
GeneTree (enSembl)ENSG00000172367
Phylogenetic Trees/Animal Genes : TreeFamPDZD3
HOVERGENQ86UT5
HOGENOMQ86UT5
Homologs : HomoloGenePDZD3
Homology/Alignments : Family Browser (UCSC)PDZD3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPDZD3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PDZD3
dbVarPDZD3
ClinVarPDZD3
1000_GenomesPDZD3 
Exome Variant ServerPDZD3
ExAC (Exome Aggregation Consortium)PDZD3 (select the gene name)
Genetic variants : HAPMAP79849
Genomic Variants (DGV)PDZD3 [DGVbeta]
DECIPHERPDZD3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPDZD3 
Mutations
ICGC Data PortalPDZD3 
TCGA Data PortalPDZD3 
Broad Tumor PortalPDZD3
OASIS PortalPDZD3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPDZD3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPDZD3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PDZD3
DgiDB (Drug Gene Interaction Database)PDZD3
DoCM (Curated mutations)PDZD3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PDZD3 (select a term)
intoGenPDZD3
Cancer3DPDZD3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607146   
Orphanet
MedgenPDZD3
Genetic Testing Registry PDZD3
NextProtQ86UT5 [Medical]
TSGene79849
GENETestsPDZD3
Target ValidationPDZD3
Huge Navigator PDZD3 [HugePedia]
snp3D : Map Gene to Disease79849
BioCentury BCIQPDZD3
ClinGenPDZD3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD79849
Chemical/Pharm GKB GenePA134911718
Clinical trialPDZD3
Miscellaneous
canSAR (ICR)PDZD3 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePDZD3
EVEXPDZD3
GoPubMedPDZD3
iHOPPDZD3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:36:01 CEST 2017

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