Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

PDZRN4 (PDZ domain containing ring finger 4)

Identity

Alias (NCBI)LNX4
SAMCAP3L
HGNC (Hugo) PDZRN4
HGNC Alias symbDKFZp434B0417
LNX4
FLJ33777
IMAGE5767589
HGNC Alias namesimilar to semaF cytoplasmic domain associated protein 3
LocusID (NCBI) 29951
Atlas_Id 47446
Location 12q12  [Link to chromosome band 12q12]
Location_base_pair Starts at 41437739 and ends at 41574745 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
AAK1 (2p13.3) / PDZRN4 (12q12)CCDC91 (12p11.22) / PDZRN4 (12q12)FOCAD (9p21.3) / PDZRN4 (12q12)
PDZRN4 (12q12) / CPM (12q15)PHACTR2 (6q24.2) / PDZRN4 (12q12)TOMM40 (19q13.32) / PDZRN4 (12q12)
TPD52L2 (20q13.33) / PDZRN4 (12q12)CCDC91 12p11.22 / PDZRN4 12q12KIAA1797 PDZRN4 12q12
PDZRN4 12q12 / CPM 12q15TOMM40 19q13.32 / PDZRN4 12q12TPD52L2 20q13.33 / PDZRN4 12q12

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)PDZRN4   30552
Cards
Entrez_Gene (NCBI)PDZRN4    PDZ domain containing ring finger 4
AliasesLNX4; SAMCAP3L
GeneCards (Weizmann)PDZRN4
Ensembl hg19 (Hinxton)ENSG00000165966 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000165966 [Gene_View]  ENSG00000165966 [Sequence]  chr12:41437739-41574745 [Contig_View]  PDZRN4 [Vega]
ICGC DataPortalENSG00000165966
TCGA cBioPortalPDZRN4
AceView (NCBI)PDZRN4
Genatlas (Paris)PDZRN4
SOURCE (Princeton)PDZRN4
Genetics Home Reference (NIH)PDZRN4
Genomic and cartography
GoldenPath hg38 (UCSC)PDZRN4  -     chr12:41437739-41574745 +  12q12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PDZRN4  -     12q12   [Description]    (hg19-Feb_2009)
GoldenPathPDZRN4 - 12q12 [CytoView hg19]  PDZRN4 - 12q12 [CytoView hg38]
ImmunoBaseENSG00000165966
Genome Data Viewer NCBIPDZRN4 [Mapview hg19]  
OMIM609730   
Gene and transcription
Genbank (Entrez)AK091096 AK094690 AK131554 AK294431 AK294535
RefSeq transcript (Entrez)NM_001164595 NM_013377
Consensus coding sequences : CCDS (NCBI)PDZRN4
Gene ExpressionPDZRN4 [ NCBI-GEO ]   PDZRN4 [ EBI - ARRAY_EXPRESS ]   PDZRN4 [ SEEK ]   PDZRN4 [ MEM ]
Gene Expression Viewer (FireBrowse)PDZRN4 [ Firebrowse - Broad ]
GenevisibleExpression of PDZRN4 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)29951
GTEX Portal (Tissue expression)PDZRN4
Human Protein AtlasENSG00000165966-PDZRN4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6ZMN7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6ZMN7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6ZMN7
PhosPhoSitePlusQ6ZMN7
Domaine pattern : Prosite (Expaxy)PDZ (PS50106)    ZF_RING_1 (PS00518)    ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)PDZ    PDZ_sf    TRAF-like    Znf_RING    Znf_RING/FYVE/PHD    Znf_RING_CS   
Domain families : Pfam (Sanger)PDZ (PF00595)   
Domain families : Pfam (NCBI)pfam00595   
Domain families : Smart (EMBL)PDZ (SM00228)  RING (SM00184)  
Conserved Domain (NCBI)PDZRN4
SuperfamilyQ6ZMN7
AlphaFold pdb e-kbQ6ZMN7   
Human Protein Atlas [tissue]ENSG00000165966-PDZRN4 [tissue]
HPRD15116
Protein Interaction databases
DIP (DOE-UCLA)Q6ZMN7
IntAct (EBI)Q6ZMN7
BioGRIDPDZRN4
STRING (EMBL)PDZRN4
ZODIACPDZRN4
Ontologies - Pathways
QuickGOQ6ZMN7
Ontology : AmiGOmetal ion binding  
Ontology : EGO-EBImetal ion binding  
NDEx NetworkPDZRN4
Atlas of Cancer Signalling NetworkPDZRN4
Wikipedia pathwaysPDZRN4
Orthology - Evolution
OrthoDB29951
GeneTree (enSembl)ENSG00000165966
Phylogenetic Trees/Animal Genes : TreeFamPDZRN4
Homologs : HomoloGenePDZRN4
Homology/Alignments : Family Browser (UCSC)PDZRN4
Gene fusions - Rearrangements
Fusion : MitelmanCCDC91/PDZRN4 [12p11.22/12q12]  
Fusion : MitelmanFOCAD/PDZRN4 [9p21.3/12q12]  
Fusion : MitelmanTOMM40/PDZRN4 [19q13.32/12q12]  
Fusion : MitelmanTPD52L2/PDZRN4 [20q13.33/12q12]  
Fusion : QuiverPDZRN4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPDZRN4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PDZRN4
dbVarPDZRN4
ClinVarPDZRN4
MonarchPDZRN4
1000_GenomesPDZRN4 
Exome Variant ServerPDZRN4
GNOMAD BrowserENSG00000165966
Varsome BrowserPDZRN4
ACMGPDZRN4 variants
VarityQ6ZMN7
Genomic Variants (DGV)PDZRN4 [DGVbeta]
DECIPHERPDZRN4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPDZRN4 
Mutations
ICGC Data PortalPDZRN4 
TCGA Data PortalPDZRN4 
Broad Tumor PortalPDZRN4
OASIS PortalPDZRN4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPDZRN4  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DPDZRN4
Mutations and Diseases : HGMDPDZRN4
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaPDZRN4
DgiDB (Drug Gene Interaction Database)PDZRN4
DoCM (Curated mutations)PDZRN4
CIViC (Clinical Interpretations of Variants in Cancer)PDZRN4
Cancer3DPDZRN4
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609730   
Orphanet
DisGeNETPDZRN4
MedgenPDZRN4
Genetic Testing Registry PDZRN4
NextProtQ6ZMN7 [Medical]
GENETestsPDZRN4
Target ValidationPDZRN4
Huge Navigator PDZRN4 [HugePedia]
ClinGenPDZRN4
Clinical trials, drugs, therapy
MyCancerGenomePDZRN4
Protein Interactions : CTDPDZRN4
Pharm GKB GenePA134974780
PharosQ6ZMN7
Clinical trialPDZRN4
Miscellaneous
canSAR (ICR)PDZRN4
HarmonizomePDZRN4
DataMed IndexPDZRN4
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXPDZRN4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 15:24:53 CEST 2021

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.