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PEAK1 (pseudopodium enriched atypical kinase 1)

Identity

Alias_symbol (synonym)KIAA2002
sgk269
Other aliasSGK269
HGNC (Hugo) PEAK1
LocusID (NCBI) 79834
Atlas_Id 53735
Location 15q24.3  [Link to chromosome band 15q24]
Location_base_pair Starts at 77108156 and ends at 77420104 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
COL1A1 (17q21.33) / PEAK1 (15q24.3)EVI5 (1p22.1) / PEAK1 (15q24.3)SVIL (10p11.23) / PEAK1 (15q24.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PEAK1   29431
Cards
Entrez_Gene (NCBI)PEAK1  79834  pseudopodium enriched atypical kinase 1
AliasesSGK269
GeneCards (Weizmann)PEAK1
Ensembl hg19 (Hinxton)ENSG00000173517 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000173517 [Gene_View]  chr15:77108156-77420104 [Contig_View]  PEAK1 [Vega]
ICGC DataPortalENSG00000173517
TCGA cBioPortalPEAK1
AceView (NCBI)PEAK1
Genatlas (Paris)PEAK1
WikiGenes79834
SOURCE (Princeton)PEAK1
Genetics Home Reference (NIH)PEAK1
Genomic and cartography
GoldenPath hg38 (UCSC)PEAK1  -     chr15:77108156-77420104 -  15q24.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PEAK1  -     15q24.3   [Description]    (hg19-Feb_2009)
EnsemblPEAK1 - 15q24.3 [CytoView hg19]  PEAK1 - 15q24.3 [CytoView hg38]
Mapping of homologs : NCBIPEAK1 [Mapview hg19]  PEAK1 [Mapview hg38]
OMIM614248   
Gene and transcription
Genbank (Entrez)AB082533 AF086416 AF088077 AK024793 AK025943
RefSeq transcript (Entrez)NM_024776
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PEAK1
Cluster EST : UnigeneHs.731402 [ NCBI ]
CGAP (NCI)Hs.731402
Alternative Splicing GalleryENSG00000173517
Gene ExpressionPEAK1 [ NCBI-GEO ]   PEAK1 [ EBI - ARRAY_EXPRESS ]   PEAK1 [ SEEK ]   PEAK1 [ MEM ]
Gene Expression Viewer (FireBrowse)PEAK1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79834
GTEX Portal (Tissue expression)PEAK1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H792   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H792  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H792
Splice isoforms : SwissVarQ9H792
Catalytic activity : Enzyme2.7.10.2 [ Enzyme-Expasy ]   2.7.10.22.7.10.2 [ IntEnz-EBI ]   2.7.10.2 [ BRENDA ]   2.7.10.2 [ KEGG ]   
PhosPhoSitePlusQ9H792
Domaine pattern : Prosite (Expaxy)PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_TYR (PS00109)   
Domains : Interpro (EBI)Kinase-like_dom    Prot_kinase_dom    Tyr_kinase_AS   
Domain families : Pfam (Sanger)Pkinase (PF00069)   
Domain families : Pfam (NCBI)pfam00069   
Domain families : Smart (EMBL)S_TKc (SM00220)  
Conserved Domain (NCBI)PEAK1
DMDM Disease mutations79834
Blocks (Seattle)PEAK1
SuperfamilyQ9H792
Human Protein AtlasENSG00000173517
Peptide AtlasQ9H792
IPIIPI00737545   
Protein Interaction databases
DIP (DOE-UCLA)Q9H792
IntAct (EBI)Q9H792
FunCoupENSG00000173517
BioGRIDPEAK1
STRING (EMBL)PEAK1
ZODIACPEAK1
Ontologies - Pathways
QuickGOQ9H792
Ontology : AmiGOnon-membrane spanning protein tyrosine kinase activity  protein binding  ATP binding  cytoplasm  focal adhesion  actin cytoskeleton  cell migration  peptidyl-tyrosine phosphorylation  substrate adhesion-dependent cell spreading  protein autophosphorylation  
Ontology : EGO-EBInon-membrane spanning protein tyrosine kinase activity  protein binding  ATP binding  cytoplasm  focal adhesion  actin cytoskeleton  cell migration  peptidyl-tyrosine phosphorylation  substrate adhesion-dependent cell spreading  protein autophosphorylation  
NDEx NetworkPEAK1
Atlas of Cancer Signalling NetworkPEAK1
Wikipedia pathwaysPEAK1
Orthology - Evolution
OrthoDB79834
GeneTree (enSembl)ENSG00000173517
Phylogenetic Trees/Animal Genes : TreeFamPEAK1
HOVERGENQ9H792
HOGENOMQ9H792
Homologs : HomoloGenePEAK1
Homology/Alignments : Family Browser (UCSC)PEAK1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPEAK1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PEAK1
dbVarPEAK1
ClinVarPEAK1
1000_GenomesPEAK1 
Exome Variant ServerPEAK1
ExAC (Exome Aggregation Consortium)PEAK1 (select the gene name)
Genetic variants : HAPMAP79834
Genomic Variants (DGV)PEAK1 [DGVbeta]
DECIPHERPEAK1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPEAK1 
Mutations
ICGC Data PortalPEAK1 
TCGA Data PortalPEAK1 
Broad Tumor PortalPEAK1
OASIS PortalPEAK1 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDPEAK1
BioMutasearch PEAK1
DgiDB (Drug Gene Interaction Database)PEAK1
DoCM (Curated mutations)PEAK1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PEAK1 (select a term)
intoGenPEAK1
Cancer3DPEAK1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614248   
Orphanet
MedgenPEAK1
Genetic Testing Registry PEAK1
NextProtQ9H792 [Medical]
TSGene79834
GENETestsPEAK1
Target ValidationPEAK1
Huge Navigator PEAK1 [HugePedia]
snp3D : Map Gene to Disease79834
BioCentury BCIQPEAK1
ClinGenPEAK1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD79834
Chemical/Pharm GKB GenePA166123722
Clinical trialPEAK1
Miscellaneous
canSAR (ICR)PEAK1 (select the gene name)
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePEAK1
EVEXPEAK1
GoPubMedPEAK1
iHOPPEAK1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:49:03 CEST 2017

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