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PEAR1 (platelet endothelial aggregation receptor 1)

Identity

Alias_namesMEGF12
multiple EGF-like-domains 12
Alias_symbol (synonym)JEDI
FLJ00193
Other alias
HGNC (Hugo) PEAR1
LocusID (NCBI) 375033
Atlas_Id 71822
Location 1q23.1  [Link to chromosome band 1q23]
Location_base_pair Starts at 156893731 and ends at 156916434 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PEAR1   33631
Cards
Entrez_Gene (NCBI)PEAR1  375033  platelet endothelial aggregation receptor 1
AliasesJEDI; MEGF12
GeneCards (Weizmann)PEAR1
Ensembl hg19 (Hinxton)ENSG00000187800 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000187800 [Gene_View]  chr1:156893731-156916434 [Contig_View]  PEAR1 [Vega]
ICGC DataPortalENSG00000187800
TCGA cBioPortalPEAR1
AceView (NCBI)PEAR1
Genatlas (Paris)PEAR1
WikiGenes375033
SOURCE (Princeton)PEAR1
Genetics Home Reference (NIH)PEAR1
Genomic and cartography
GoldenPath hg38 (UCSC)PEAR1  -     chr1:156893731-156916434 +  1q23.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PEAR1  -     1q23.1   [Description]    (hg19-Feb_2009)
EnsemblPEAR1 - 1q23.1 [CytoView hg19]  PEAR1 - 1q23.1 [CytoView hg38]
Mapping of homologs : NCBIPEAR1 [Mapview hg19]  PEAR1 [Mapview hg38]
OMIM610278   
Gene and transcription
Genbank (Entrez)AK074121 AK098809 BC172296
RefSeq transcript (Entrez)NM_001080471 NM_207369
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PEAR1
Cluster EST : UnigeneHs.142003 [ NCBI ]
CGAP (NCI)Hs.142003
Alternative Splicing GalleryENSG00000187800
Gene ExpressionPEAR1 [ NCBI-GEO ]   PEAR1 [ EBI - ARRAY_EXPRESS ]   PEAR1 [ SEEK ]   PEAR1 [ MEM ]
Gene Expression Viewer (FireBrowse)PEAR1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)375033
GTEX Portal (Tissue expression)PEAR1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5VY43   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5VY43  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5VY43
Splice isoforms : SwissVarQ5VY43
PhosPhoSitePlusQ5VY43
Domaine pattern : Prosite (Expaxy)EGF_1 (PS00022)    EGF_2 (PS01186)    EGF_3 (PS50026)    EMI (PS51041)   
Domains : Interpro (EBI)EGF-like_CS    EGF-like_dom    EMI_domain    Laminin_EGF   
Domain families : Pfam (Sanger)Laminin_EGF (PF00053)   
Domain families : Pfam (NCBI)pfam00053   
Domain families : Smart (EMBL)EGF (SM00181)  EGF_Lam (SM00180)  
Conserved Domain (NCBI)PEAR1
DMDM Disease mutations375033
Blocks (Seattle)PEAR1
SuperfamilyQ5VY43
Human Protein AtlasENSG00000187800
Peptide AtlasQ5VY43
IPIIPI00154858   IPI00167128   IPI00853106   IPI00787779   
Protein Interaction databases
DIP (DOE-UCLA)Q5VY43
IntAct (EBI)Q5VY43
FunCoupENSG00000187800
BioGRIDPEAR1
STRING (EMBL)PEAR1
ZODIACPEAR1
Ontologies - Pathways
QuickGOQ5VY43
Ontology : AmiGOphagocytic cup  integral component of membrane  recognition of apoptotic cell  negative regulation of Notch signaling pathway  
Ontology : EGO-EBIphagocytic cup  integral component of membrane  recognition of apoptotic cell  negative regulation of Notch signaling pathway  
NDEx NetworkPEAR1
Atlas of Cancer Signalling NetworkPEAR1
Wikipedia pathwaysPEAR1
Orthology - Evolution
OrthoDB375033
GeneTree (enSembl)ENSG00000187800
Phylogenetic Trees/Animal Genes : TreeFamPEAR1
HOVERGENQ5VY43
HOGENOMQ5VY43
Homologs : HomoloGenePEAR1
Homology/Alignments : Family Browser (UCSC)PEAR1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPEAR1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PEAR1
dbVarPEAR1
ClinVarPEAR1
1000_GenomesPEAR1 
Exome Variant ServerPEAR1
ExAC (Exome Aggregation Consortium)PEAR1 (select the gene name)
Genetic variants : HAPMAP375033
Genomic Variants (DGV)PEAR1 [DGVbeta]
DECIPHERPEAR1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPEAR1 
Mutations
ICGC Data PortalPEAR1 
TCGA Data PortalPEAR1 
Broad Tumor PortalPEAR1
OASIS PortalPEAR1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPEAR1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPEAR1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PEAR1
DgiDB (Drug Gene Interaction Database)PEAR1
DoCM (Curated mutations)PEAR1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PEAR1 (select a term)
intoGenPEAR1
Cancer3DPEAR1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610278   
Orphanet
MedgenPEAR1
Genetic Testing Registry PEAR1
NextProtQ5VY43 [Medical]
TSGene375033
GENETestsPEAR1
Target ValidationPEAR1
Huge Navigator PEAR1 [HugePedia]
snp3D : Map Gene to Disease375033
BioCentury BCIQPEAR1
ClinGenPEAR1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD375033
Chemical/Pharm GKB GenePA162399233
Clinical trialPEAR1
Miscellaneous
canSAR (ICR)PEAR1 (select the gene name)
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePEAR1
EVEXPEAR1
GoPubMedPEAR1
iHOPPEAR1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:36:02 CEST 2017

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