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PELI3 (pellino E3 ubiquitin protein ligase family member 3)

Identity

Alias_namespellino homolog 3 (Drosophila)
Alias_symbol (synonym)MGC35521
Other alias-
HGNC (Hugo) PELI3
LocusID (NCBI) 246330
Atlas_Id 53876
Location 11q13.2  [Link to chromosome band 11q13]
Location_base_pair Starts at 66234336 and ends at 66244808 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
CAPN5 (11q13.5) / PELI3 (11q13.2)PLEKHA6 (1q32.1) / PELI3 (11q13.2)CAPN5 11q13.5 / PELI3 11q13.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PELI3   30010
Cards
Entrez_Gene (NCBI)PELI3  246330  pellino E3 ubiquitin protein ligase family member 3
Aliases
GeneCards (Weizmann)PELI3
Ensembl hg19 (Hinxton)ENSG00000174516 [Gene_View]  chr11:66234336-66244808 [Contig_View]  PELI3 [Vega]
Ensembl hg38 (Hinxton)ENSG00000174516 [Gene_View]  chr11:66234336-66244808 [Contig_View]  PELI3 [Vega]
ICGC DataPortalENSG00000174516
TCGA cBioPortalPELI3
AceView (NCBI)PELI3
Genatlas (Paris)PELI3
WikiGenes246330
SOURCE (Princeton)PELI3
Genetics Home Reference (NIH)PELI3
Genomic and cartography
GoldenPath hg19 (UCSC)PELI3  -     chr11:66234336-66244808 +  11q13.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)PELI3  -     11q13.2   [Description]    (hg38-Dec_2013)
EnsemblPELI3 - 11q13.2 [CytoView hg19]  PELI3 - 11q13.2 [CytoView hg38]
Mapping of homologs : NCBIPELI3 [Mapview hg19]  PELI3 [Mapview hg38]
OMIM609827   
Gene and transcription
Genbank (Entrez)AF487456 AF487457 AK074201 AK075253 AK094060
RefSeq transcript (Entrez)NM_001098510 NM_001243135 NM_001243136 NM_145065
RefSeq genomic (Entrez)NC_000011 NC_018922 NG_029627 NT_167190 NW_004929380
Consensus coding sequences : CCDS (NCBI)PELI3
Cluster EST : UnigeneHs.656875 [ NCBI ]
CGAP (NCI)Hs.656875
Alternative Splicing GalleryENSG00000174516
Gene ExpressionPELI3 [ NCBI-GEO ]   PELI3 [ EBI - ARRAY_EXPRESS ]   PELI3 [ SEEK ]   PELI3 [ MEM ]
Gene Expression Viewer (FireBrowse)PELI3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)246330
GTEX Portal (Tissue expression)PELI3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N2H9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N2H9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N2H9
Splice isoforms : SwissVarQ8N2H9
PhosPhoSitePlusQ8N2H9
Domains : Interpro (EBI)Pellino_fam   
Domain families : Pfam (Sanger)Pellino (PF04710)   
Domain families : Pfam (NCBI)pfam04710   
Conserved Domain (NCBI)PELI3
DMDM Disease mutations246330
Blocks (Seattle)PELI3
SuperfamilyQ8N2H9
Human Protein AtlasENSG00000174516
Peptide AtlasQ8N2H9
HPRD17535
IPIIPI00296429   IPI00152141   IPI00167786   IPI00377193   IPI00976975   IPI00979611   IPI00976257   IPI00978997   
Protein Interaction databases
DIP (DOE-UCLA)Q8N2H9
IntAct (EBI)Q8N2H9
FunCoupENSG00000174516
BioGRIDPELI3
STRING (EMBL)PELI3
ZODIACPELI3
Ontologies - Pathways
QuickGOQ8N2H9
Ontology : AmiGOprotein binding  cytosol  Toll signaling pathway  negative regulation of tumor necrosis factor-mediated signaling pathway  protein ubiquitination  ligase activity  negative regulation of extrinsic apoptotic signaling pathway  
Ontology : EGO-EBIprotein binding  cytosol  Toll signaling pathway  negative regulation of tumor necrosis factor-mediated signaling pathway  protein ubiquitination  ligase activity  negative regulation of extrinsic apoptotic signaling pathway  
NDEx NetworkPELI3
Atlas of Cancer Signalling NetworkPELI3
Wikipedia pathwaysPELI3
Orthology - Evolution
OrthoDB246330
GeneTree (enSembl)ENSG00000174516
Phylogenetic Trees/Animal Genes : TreeFamPELI3
HOVERGENQ8N2H9
HOGENOMQ8N2H9
Homologs : HomoloGenePELI3
Homology/Alignments : Family Browser (UCSC)PELI3
Gene fusions - Rearrangements
Fusion : MitelmanCAPN5/PELI3 [11q13.5/11q13.2]  [t(11;11)(q13;q13)]  
Fusion: TCGACAPN5 11q13.5 PELI3 11q13.2 LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPELI3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PELI3
dbVarPELI3
ClinVarPELI3
1000_GenomesPELI3 
Exome Variant ServerPELI3
ExAC (Exome Aggregation Consortium)PELI3 (select the gene name)
Genetic variants : HAPMAP246330
Genomic Variants (DGV)PELI3 [DGVbeta]
DECIPHER (Syndromes)11:66234336-66244808  ENSG00000174516
CONAN: Copy Number AnalysisPELI3 
Mutations
ICGC Data PortalPELI3 
TCGA Data PortalPELI3 
Broad Tumor PortalPELI3
OASIS PortalPELI3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPELI3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPELI3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PELI3
DgiDB (Drug Gene Interaction Database)PELI3
DoCM (Curated mutations)PELI3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PELI3 (select a term)
intoGenPELI3
Cancer3DPELI3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609827   
Orphanet
MedgenPELI3
Genetic Testing Registry PELI3
NextProtQ8N2H9 [Medical]
TSGene246330
GENETestsPELI3
Huge Navigator PELI3 [HugePedia]
snp3D : Map Gene to Disease246330
BioCentury BCIQPELI3
ClinGenPELI3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD246330
Chemical/Pharm GKB GenePA142671185
Clinical trialPELI3
Miscellaneous
canSAR (ICR)PELI3 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePELI3
EVEXPELI3
GoPubMedPELI3
iHOPPELI3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:14:01 CEST 2017

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