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PELI3 (pellino E3 ubiquitin protein ligase family member 3)

Identity

Alias (NCBI)-
HGNC (Hugo) PELI3
HGNC Alias symbMGC35521
HGNC Previous namepellino homolog 3 (Drosophila)
LocusID (NCBI) 246330
Atlas_Id 53876
Location 11q13.2  [Link to chromosome band 11q13]
Location_base_pair Starts at 66466905 and ends at 66477337 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CAPN5 (11q13.5) / PELI3 (11q13.2)PLEKHA6 (1q32.1) / PELI3 (11q13.2)CAPN5 11q13.5 / PELI3 11q13.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)PELI3   30010
Cards
Entrez_Gene (NCBI)PELI3    pellino E3 ubiquitin protein ligase family member 3
Aliases
GeneCards (Weizmann)PELI3
Ensembl hg19 (Hinxton)ENSG00000174516 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000174516 [Gene_View]  ENSG00000174516 [Sequence]  chr11:66466905-66477337 [Contig_View]  PELI3 [Vega]
ICGC DataPortalENSG00000174516
TCGA cBioPortalPELI3
AceView (NCBI)PELI3
Genatlas (Paris)PELI3
SOURCE (Princeton)PELI3
Genetics Home Reference (NIH)PELI3
Genomic and cartography
GoldenPath hg38 (UCSC)PELI3  -     chr11:66466905-66477337 +  11q13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PELI3  -     11q13.2   [Description]    (hg19-Feb_2009)
GoldenPathPELI3 - 11q13.2 [CytoView hg19]  PELI3 - 11q13.2 [CytoView hg38]
ImmunoBaseENSG00000174516
Genome Data Viewer NCBIPELI3 [Mapview hg19]  
OMIM609827   
Gene and transcription
Genbank (Entrez)AF487456 AF487457 AK074201 AK075253 AK094060
RefSeq transcript (Entrez)NM_001098510 NM_001243135 NM_001243136 NM_145065
Consensus coding sequences : CCDS (NCBI)PELI3
Gene ExpressionPELI3 [ NCBI-GEO ]   PELI3 [ EBI - ARRAY_EXPRESS ]   PELI3 [ SEEK ]   PELI3 [ MEM ]
Gene Expression Viewer (FireBrowse)PELI3 [ Firebrowse - Broad ]
GenevisibleExpression of PELI3 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)246330
GTEX Portal (Tissue expression)PELI3
Human Protein AtlasENSG00000174516-PELI3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N2H9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N2H9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N2H9
Catalytic activity : Enzyme2.3.2.27 [ Enzyme-Expasy ]   2.3.2.272.3.2.27 [ IntEnz-EBI ]   2.3.2.27 [ BRENDA ]   2.3.2.27 [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusQ8N2H9
Domains : Interpro (EBI)Pellino_fam   
Domain families : Pfam (Sanger)Pellino (PF04710)   
Domain families : Pfam (NCBI)pfam04710   
Conserved Domain (NCBI)PELI3
SuperfamilyQ8N2H9
AlphaFold pdb e-kbQ8N2H9   
Human Protein Atlas [tissue]ENSG00000174516-PELI3 [tissue]
HPRD17535
Protein Interaction databases
DIP (DOE-UCLA)Q8N2H9
IntAct (EBI)Q8N2H9
BioGRIDPELI3
STRING (EMBL)PELI3
ZODIACPELI3
Ontologies - Pathways
QuickGOQ8N2H9
Ontology : AmiGOprotein polyubiquitination  protein binding  cytosol  Toll signaling pathway  regulation of Toll signaling pathway  negative regulation of tumor necrosis factor-mediated signaling pathway  ubiquitin protein ligase activity  interleukin-1-mediated signaling pathway  protein K63-linked ubiquitination  negative regulation of extrinsic apoptotic signaling pathway  
Ontology : EGO-EBIprotein polyubiquitination  protein binding  cytosol  Toll signaling pathway  regulation of Toll signaling pathway  negative regulation of tumor necrosis factor-mediated signaling pathway  ubiquitin protein ligase activity  interleukin-1-mediated signaling pathway  protein K63-linked ubiquitination  negative regulation of extrinsic apoptotic signaling pathway  
NDEx NetworkPELI3
Atlas of Cancer Signalling NetworkPELI3
Wikipedia pathwaysPELI3
Orthology - Evolution
OrthoDB246330
GeneTree (enSembl)ENSG00000174516
Phylogenetic Trees/Animal Genes : TreeFamPELI3
Homologs : HomoloGenePELI3
Homology/Alignments : Family Browser (UCSC)PELI3
Gene fusions - Rearrangements
Fusion : MitelmanCAPN5/PELI3 [11q13.5/11q13.2]  
Fusion : QuiverPELI3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPELI3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PELI3
dbVarPELI3
ClinVarPELI3
MonarchPELI3
1000_GenomesPELI3 
Exome Variant ServerPELI3
GNOMAD BrowserENSG00000174516
Varsome BrowserPELI3
ACMGPELI3 variants
VarityQ8N2H9
Genomic Variants (DGV)PELI3 [DGVbeta]
DECIPHERPELI3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPELI3 
Mutations
ICGC Data PortalPELI3 
TCGA Data PortalPELI3 
Broad Tumor PortalPELI3
OASIS PortalPELI3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPELI3  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DPELI3
Mutations and Diseases : HGMDPELI3
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaPELI3
DgiDB (Drug Gene Interaction Database)PELI3
DoCM (Curated mutations)PELI3
CIViC (Clinical Interpretations of Variants in Cancer)PELI3
Cancer3DPELI3
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609827   
Orphanet
DisGeNETPELI3
MedgenPELI3
Genetic Testing Registry PELI3
NextProtQ8N2H9 [Medical]
GENETestsPELI3
Target ValidationPELI3
Huge Navigator PELI3 [HugePedia]
ClinGenPELI3
Clinical trials, drugs, therapy
MyCancerGenomePELI3
Protein Interactions : CTDPELI3
Pharm GKB GenePA142671185
PharosQ8N2H9
Clinical trialPELI3
Miscellaneous
canSAR (ICR)PELI3
HarmonizomePELI3
DataMed IndexPELI3
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXPELI3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:24:54 CEST 2021

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