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PEPD (peptidase D)

Identity

Other namesPROLIDASE
HGNC (Hugo) PEPD
LocusID (NCBI) 5184
Atlas_Id 47595
Location 19q13.11
Location_base_pair Starts at 33877855 and ends at 34012799 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
CDR2L (17q25.1) / PEPD (19q13.11)CEP89 (19q13.11) / PEPD (19q13.11)HDAC1 (1p35.1) / PEPD (19q13.11)
MRPL35 (2p11.2) / PEPD (19q13.11)MXI1 (10q25.2) / PEPD (19q13.11)PEPD (19q13.11) / AC011497.1 ()
PEPD (19q13.11) / RELB (19q13.32)PEPD (19q13.11) / SKAP1 (17q21.32)RHPN2 (19q13.11) / PEPD (19q13.11)
HDAC1 1p35.1 / PEPD 19q13.11PEPD 19q13.11 AC011497.1PEPD 19q13.11 / SKAP1 17q21.32
RHPN2 19q13.11 / PEPD 19q13.11

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PEPD   8840
Cards
Entrez_Gene (NCBI)PEPD  5184  peptidase D
AliasesPROLIDASE
GeneCards (Weizmann)PEPD
Ensembl hg19 (Hinxton)ENSG00000124299 [Gene_View]  chr19:33877855-34012799 [Contig_View]  PEPD [Vega]
Ensembl hg38 (Hinxton)ENSG00000124299 [Gene_View]  chr19:33877855-34012799 [Contig_View]  PEPD [Vega]
ICGC DataPortalENSG00000124299
TCGA cBioPortalPEPD
AceView (NCBI)PEPD
Genatlas (Paris)PEPD
WikiGenes5184
SOURCE (Princeton)PEPD
Genomic and cartography
GoldenPath hg19 (UCSC)PEPD  -     chr19:33877855-34012799 -  19q13.11   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)PEPD  -     19q13.11   [Description]    (hg38-Dec_2013)
EnsemblPEPD - 19q13.11 [CytoView hg19]  PEPD - 19q13.11 [CytoView hg38]
Mapping of homologs : NCBIPEPD [Mapview hg19]  PEPD [Mapview hg38]
OMIM170100   613230   
Gene and transcription
Genbank (Entrez)AK057538 AK225037 AK290756 AK290781 AK291561
RefSeq transcript (Entrez)NM_000285 NM_001166056 NM_001166057
RefSeq genomic (Entrez)NC_000019 NC_018930 NG_013358 NT_011109 NW_004929415
Consensus coding sequences : CCDS (NCBI)PEPD
Cluster EST : UnigeneHs.36473 [ NCBI ]
CGAP (NCI)Hs.36473
Alternative Splicing GalleryENSG00000124299
Gene ExpressionPEPD [ NCBI-GEO ]   PEPD [ EBI - ARRAY_EXPRESS ]   PEPD [ SEEK ]   PEPD [ MEM ]
Gene Expression Viewer (FireBrowse)PEPD [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5184
GTEX Portal (Tissue expression)PEPD
Protein : pattern, domain, 3D structure
UniProt/SwissProtP12955 (Uniprot)
NextProtP12955  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP12955
Splice isoforms : SwissVarP12955 (Swissvar)
Catalytic activity : Enzyme3.4.13.9 [ Enzyme-Expasy ]   3.4.13.93.4.13.9 [ IntEnz-EBI ]   3.4.13.9 [ BRENDA ]   3.4.13.9 [ KEGG ]   
PhosPhoSitePlusP12955
Domaine pattern : Prosite (Expaxy)PROLINE_PEPTIDASE (PS00491)   
Domains : Interpro (EBI)Aminopep_P_N    Creatin/AminoP/Spt16_NTD    Creatinase/Aminopeptidase_P_N    Pept_M24_structural-domain    Peptidase_M24B_aminopep-P_CS   
Domain families : Pfam (Sanger)AMP_N (PF05195)    Peptidase_M24 (PF00557)   
Domain families : Pfam (NCBI)pfam05195    pfam00557   
Domain families : Smart (EMBL)AMP_N (SM01011)  
DMDM Disease mutations5184
Blocks (Seattle)PEPD
PDB (SRS)2IW2    2OKN   
PDB (PDBSum)2IW2    2OKN   
PDB (IMB)2IW2    2OKN   
PDB (RSDB)2IW2    2OKN   
Structural Biology KnowledgeBase2IW2    2OKN   
SCOP (Structural Classification of Proteins)2IW2    2OKN   
CATH (Classification of proteins structures)2IW2    2OKN   
SuperfamilyP12955
Human Protein AtlasENSG00000124299
Peptide AtlasP12955
HPRD01358
IPIIPI00257882   IPI00910514   IPI00909399   
Protein Interaction databases
DIP (DOE-UCLA)P12955
IntAct (EBI)P12955
FunCoupENSG00000124299
BioGRIDPEPD
STRING (EMBL)PEPD
ZODIACPEPD
Ontologies - Pathways
QuickGOP12955
Ontology : AmiGOaminopeptidase activity  metallocarboxypeptidase activity  protein binding  proteolysis  cellular amino acid metabolic process  manganese ion binding  collagen catabolic process  extracellular exosome  proline dipeptidase activity  
Ontology : EGO-EBIaminopeptidase activity  metallocarboxypeptidase activity  protein binding  proteolysis  cellular amino acid metabolic process  manganese ion binding  collagen catabolic process  extracellular exosome  proline dipeptidase activity  
NDEx Network
Atlas of Cancer Signalling NetworkPEPD
Wikipedia pathwaysPEPD
Orthology - Evolution
OrthoDB5184
GeneTree (enSembl)ENSG00000124299
Phylogenetic Trees/Animal Genes : TreeFamPEPD
Homologs : HomoloGenePEPD
Homology/Alignments : Family Browser (UCSC)PEPD
Gene fusions - Rearrangements
Fusion: TCGAHDAC1 1p35.1 PEPD 19q13.11 BLCA
Fusion: TCGAPEPD 19q13.11 AC011497.1 HNSC
Fusion: TCGAPEPD 19q13.11 SKAP1 17q21.32 LUAD
Fusion: TCGARHPN2 19q13.11 PEPD 19q13.11 BLCA
Polymorphisms : SNP, variants
NCBI Variation ViewerPEPD [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PEPD
dbVarPEPD
ClinVarPEPD
1000_GenomesPEPD 
Exome Variant ServerPEPD
ExAC (Exome Aggregation Consortium)PEPD (select the gene name)
Genetic variants : HAPMAP5184
Genomic Variants (DGV)PEPD [DGVbeta]
Mutations
ICGC Data PortalPEPD 
TCGA Data PortalPEPD 
Broad Tumor PortalPEPD
OASIS PortalPEPD [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPEPD 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PEPD
DgiDB (Drug Gene Interaction Database)PEPD
DoCM (Curated mutations)PEPD (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PEPD (select a term)
intoGenPEPD
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)19:33877855-34012799  ENSG00000124299
CONAN: Copy Number AnalysisPEPD 
Mutations and Diseases : HGMDPEPD
OMIM170100    613230   
MedgenPEPD
Genetic Testing Registry PEPD
NextProtP12955 [Medical]
TSGene5184
GENETestsPEPD
Huge Navigator PEPD [HugePedia]
snp3D : Map Gene to Disease5184
BioCentury BCIQPEPD
ClinGenPEPD
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5184
Chemical/Pharm GKB GenePA33181
Clinical trialPEPD
Miscellaneous
canSAR (ICR)PEPD (select the gene name)
Probes
Litterature
PubMed86 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePEPD
EVEXPEPD
GoPubMedPEPD
iHOPPEPD
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sat May 28 11:15:26 CEST 2016

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