PEX11A (peroxisomal biogenesis factor 11 alpha)

2016-10-01  

Identity

HGNC
LOCATION
15q26.1
LOCUSID
ALIAS
PEX11-ALPHA,PMP28,hsPEX11p

Other Information

Locus ID:

NCBI: 8800
MIM: 603866
HGNC: 8852
Ensembl: ENSG00000166821

Variants:

dbSNP: 8800
ClinVar: 8800
TCGA: ENSG00000166821
COSMIC: PEX11A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000166821ENST00000300056O75192
ENSG00000166821ENST00000300056B2R8C6
ENSG00000166821ENST00000559170H0YN61
ENSG00000166821ENST00000561224H0YMC7
ENSG00000166821ENST00000561257O75192

Expression (GTEx)

0
5
10
15
20

Pathways

PathwaySourceExternal ID
PeroxisomeKEGGko04146
PeroxisomeKEGGhsa04146
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Fatty acid, triacylglycerol, and ketone body metabolismREACTOMER-HSA-535734
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)REACTOMER-HSA-400206
PPARA activates gene expressionREACTOMER-HSA-1989781

References

Pubmed IDYearTitleCitations
208264552010PEX11 family members are membrane elongation factors that coordinate peroxisome proliferation and maintenance.49
124177262002PEX11alpha is required for peroxisome proliferation in response to 4-phenylbutyrate but is dispensable for peroxisome proliferator-activated receptor alpha-mediated peroxisome proliferation.42
165674222006Peroxisome proliferator-activated receptor subtypes differentially cooperate with other transcription factors in selective transactivation of the perilipin/PEX11 alpha gene pair.6

Citation

Dessen P

PEX11A (peroxisomal biogenesis factor 11 alpha)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56585/pex11a