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PEX3 (peroxisomal biogenesis factor 3)

Identity

Alias (NCBI)PBD10A
PBD10B
TRG18
HGNC (Hugo) PEX3
LocusID (NCBI) 8504
Atlas_Id 57932
Location 6q24.2  [Link to chromosome band 6q24]
Location_base_pair Starts at 143450805 and ends at 143490614 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

Nomenclature
HGNC (Hugo)PEX3   8858
Cards
Entrez_Gene (NCBI)PEX3  8504  peroxisomal biogenesis factor 3
AliasesPBD10A; PBD10B; TRG18
GeneCards (Weizmann)PEX3
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]   [Sequence]  chr6:143450805-143490614 [Contig_View]  PEX3 [Vega]
TCGA cBioPortalPEX3
AceView (NCBI)PEX3
Genatlas (Paris)PEX3
WikiGenes8504
SOURCE (Princeton)PEX3
Genetics Home Reference (NIH)PEX3
Genomic and cartography
GoldenPath hg38 (UCSC)PEX3  -     chr6:143450805-143490614 +  6q24.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PEX3  -     6q24.2   [Description]    (hg19-Feb_2009)
GoldenPathPEX3 - 6q24.2 [CytoView hg19]  PEX3 - 6q24.2 [CytoView hg38]
genome Data Viewer NCBIPEX3 [Mapview hg19]  
OMIM603164   614882   617370   
Gene and transcription
Genbank (Entrez)AB035307 AJ001625 AJ131389 AK023593 AK025644
RefSeq transcript (Entrez)NM_003630
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PEX3
Gene ExpressionPEX3 [ NCBI-GEO ]   PEX3 [ EBI - ARRAY_EXPRESS ]   PEX3 [ SEEK ]   PEX3 [ MEM ]
Gene Expression Viewer (FireBrowse)PEX3 [ Firebrowse - Broad ]
GenevisibleExpression of PEX3 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8504
GTEX Portal (Tissue expression)PEX3
Protein : pattern, domain, 3D structure
UniProt/SwissProtP56589   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP56589  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP56589
Splice isoforms : SwissVarP56589
PhosPhoSitePlusP56589
Domains : Interpro (EBI)Peroxin-3   
Domain families : Pfam (Sanger)Peroxin-3 (PF04882)   
Domain families : Pfam (NCBI)pfam04882   
Conserved Domain (NCBI)PEX3
DMDM Disease mutations8504
Blocks (Seattle)PEX3
PDB (RSDB)3AJB    3MK4   
PDB Europe3AJB    3MK4   
PDB (PDBSum)3AJB    3MK4   
PDB (IMB)3AJB    3MK4   
Structural Biology KnowledgeBase3AJB    3MK4   
SCOP (Structural Classification of Proteins)3AJB    3MK4   
CATH (Classification of proteins structures)3AJB    3MK4   
SuperfamilyP56589
Peptide AtlasP56589
IPIIPI00010232   IPI00385462   
Protein Interaction databases
DIP (DOE-UCLA)P56589
IntAct (EBI)P56589
BioGRIDPEX3
STRING (EMBL)PEX3
ZODIACPEX3
Ontologies - Pathways
QuickGOP56589
Ontology : AmiGOprotein binding  nucleoplasm  peroxisome  peroxisome  peroxisomal membrane  peroxisomal membrane  integral component of peroxisomal membrane  integral component of peroxisomal membrane  endoplasmic reticulum  cytosol  peroxisome organization  lipid binding  membrane  peroxisome membrane biogenesis  protein binding, bridging  protein-containing complex  protein-lipid complex  protein import into peroxisome membrane  protein import into peroxisome membrane  transmembrane transport  
Ontology : EGO-EBIprotein binding  nucleoplasm  peroxisome  peroxisome  peroxisomal membrane  peroxisomal membrane  integral component of peroxisomal membrane  integral component of peroxisomal membrane  endoplasmic reticulum  cytosol  peroxisome organization  lipid binding  membrane  peroxisome membrane biogenesis  protein binding, bridging  protein-containing complex  protein-lipid complex  protein import into peroxisome membrane  protein import into peroxisome membrane  transmembrane transport  
Pathways : KEGGPeroxisome   
NDEx NetworkPEX3
Atlas of Cancer Signalling NetworkPEX3
Wikipedia pathwaysPEX3
Orthology - Evolution
OrthoDB8504
Phylogenetic Trees/Animal Genes : TreeFamPEX3
HOGENOMP56589
Homologs : HomoloGenePEX3
Homology/Alignments : Family Browser (UCSC)PEX3
Gene fusions - Rearrangements
Fusion : QuiverPEX3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPEX3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PEX3
dbVarPEX3
ClinVarPEX3
MonarchPEX3
1000_GenomesPEX3 
Exome Variant ServerPEX3
Varsome BrowserPEX3
Genetic variants : HAPMAP8504
Genomic Variants (DGV)PEX3 [DGVbeta]
DECIPHERPEX3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPEX3 
Mutations
ICGC Data PortalPEX3 
TCGA Data PortalPEX3 
Broad Tumor PortalPEX3
OASIS PortalPEX3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPEX3  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DPEX3
Mutations and Diseases : HGMDPEX3
BioMutasearch PEX3
DgiDB (Drug Gene Interaction Database)PEX3
DoCM (Curated mutations)PEX3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PEX3 (select a term)
intoGenPEX3
Cancer3DPEX3(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603164    614882    617370   
Orphanet
DisGeNETPEX3
MedgenPEX3
Genetic Testing Registry PEX3
NextProtP56589 [Medical]
TSGene8504
GENETestsPEX3
Target ValidationPEX3
Huge Navigator PEX3 [HugePedia]
snp3D : Map Gene to Disease8504
BioCentury BCIQPEX3
ClinGenPEX3
Clinical trials, drugs, therapy
Protein Interactions : CTD8504
Pharm GKB GenePA33200
Clinical trialPEX3
Miscellaneous
canSAR (ICR)PEX3 (select the gene name)
HarmonizomePEX3
DataMed IndexPEX3
Probes
Litterature
PubMed55 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePEX3
EVEXPEX3
GoPubMedPEX3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 14 14:26:24 CEST 2020

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