Identity
HGNC
LOCATION
12p13.31
LOCUSID
ALIAS
PBD2A,PBD2B,PTS1-BP,PTS1R,PXR1,RCDP5
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5830
MIM: 600414
HGNC: 9719
Ensembl: ENSG00000139197
Variants:
dbSNP: 5830
ClinVar: 5830
TCGA: ENSG00000139197
COSMIC: PEX5
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Peroxisome | KEGG | ko04146 |
| Peroxisome | KEGG | hsa04146 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38540734 | 2024 | Identification and Validation of a PEX5-Dependent Signature for Prognostic Prediction in Glioma. | 0 |
| 38540734 | 2024 | Identification and Validation of a PEX5-Dependent Signature for Prognostic Prediction in Glioma. | 0 |
| 35002522 | 2022 | Insights into the critical role of the PXR in preventing carcinogenesis and chemotherapeutic drug resistance. | 10 |
| 35002522 | 2022 | Insights into the critical role of the PXR in preventing carcinogenesis and chemotherapeutic drug resistance. | 10 |
| 33389129 | 2021 | A missense allele of PEX5 is responsible for the defective import of PTS2 cargo proteins into peroxisomes. | 3 |
| 33484719 | 2021 | Competitive Microtubule Binding of PEX14 Coordinates Peroxisomal Protein Import and Motility. | 3 |
| 33389129 | 2021 | A missense allele of PEX5 is responsible for the defective import of PTS2 cargo proteins into peroxisomes. | 3 |
| 33484719 | 2021 | Competitive Microtubule Binding of PEX14 Coordinates Peroxisomal Protein Import and Motility. | 3 |
| 32854114 | 2020 | Mitotic phosphorylation of Pex14p regulates peroxisomal import machinery. | 10 |
| 32854114 | 2020 | Mitotic phosphorylation of Pex14p regulates peroxisomal import machinery. | 10 |
| 29622767 | 2018 | PEX5 regulates autophagy via the mTORC1-TFEB axis during starvation. | 16 |
| 29884772 | 2018 | Peroxisomal monoubiquitinated PEX5 interacts with the AAA ATPases PEX1 and PEX6 and is unfolded during its dislocation into the cytosol. | 22 |
| 30204880 | 2018 | A newly isolated Pex7-binding, atypical PTS2 protein P7BP2 is a novel dynein-type AAA+ protein. | 0 |
| 30375424 | 2018 | Chemically monoubiquitinated PEX5 binds to the components of the peroxisomal docking and export machinery. | 5 |
| 29622767 | 2018 | PEX5 regulates autophagy via the mTORC1-TFEB axis during starvation. | 16 |
Citation
Dessen P
PEX5 (peroxisomal biogenesis factor 5)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45552/pex5
