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PFDN5 (prefoldin subunit 5)

Identity

Alias_namesprefoldin 5
Alias_symbol (synonym)PFD5
MM-1
Other aliasMM1
HGNC (Hugo) PFDN5
LocusID (NCBI) 5204
Atlas_Id 41694
Location 12q13.13  [Link to chromosome band 12q13]
Location_base_pair Starts at 53689235 and ends at 53693234 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
CDK2AP2 (11q13.2) / PFDN5 (12q13.13)PI4K2A (10q24.2) / PFDN5 (12q13.13)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PFDN5   8869
Cards
Entrez_Gene (NCBI)PFDN5  5204  prefoldin subunit 5
AliasesMM-1; MM1; PFD5
GeneCards (Weizmann)PFDN5
Ensembl hg19 (Hinxton)ENSG00000123349 [Gene_View]  chr12:53689235-53693234 [Contig_View]  PFDN5 [Vega]
Ensembl hg38 (Hinxton)ENSG00000123349 [Gene_View]  chr12:53689235-53693234 [Contig_View]  PFDN5 [Vega]
ICGC DataPortalENSG00000123349
TCGA cBioPortalPFDN5
AceView (NCBI)PFDN5
Genatlas (Paris)PFDN5
WikiGenes5204
SOURCE (Princeton)PFDN5
Genetics Home Reference (NIH)PFDN5
Genomic and cartography
GoldenPath hg19 (UCSC)PFDN5  -     chr12:53689235-53693234 +  12q13.13   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)PFDN5  -     12q13.13   [Description]    (hg38-Dec_2013)
EnsemblPFDN5 - 12q13.13 [CytoView hg19]  PFDN5 - 12q13.13 [CytoView hg38]
Mapping of homologs : NCBIPFDN5 [Mapview hg19]  PFDN5 [Mapview hg38]
OMIM604899   
Gene and transcription
Genbank (Entrez)AB055803 AB055804 AB055805 AK024094 AK292623
RefSeq transcript (Entrez)NM_002624 NM_145896 NM_145897
RefSeq genomic (Entrez)NC_000012 NC_018923 NG_029695 NT_029419 NW_004929384
Consensus coding sequences : CCDS (NCBI)PFDN5
Cluster EST : UnigeneHs.655327 [ NCBI ]
CGAP (NCI)Hs.655327
Alternative Splicing GalleryENSG00000123349
Gene ExpressionPFDN5 [ NCBI-GEO ]   PFDN5 [ EBI - ARRAY_EXPRESS ]   PFDN5 [ SEEK ]   PFDN5 [ MEM ]
Gene Expression Viewer (FireBrowse)PFDN5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5204
GTEX Portal (Tissue expression)PFDN5
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ99471   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ99471  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ99471
Splice isoforms : SwissVarQ99471
PhosPhoSitePlusQ99471
Domains : Interpro (EBI)PFD_alpha_archaea    Prefoldin    Prefoldin_subunit_alpha   
Domain families : Pfam (Sanger)Prefoldin (PF02996)   
Domain families : Pfam (NCBI)pfam02996   
Conserved Domain (NCBI)PFDN5
DMDM Disease mutations5204
Blocks (Seattle)PFDN5
SuperfamilyQ99471
Human Protein AtlasENSG00000123349
Peptide AtlasQ99471
IPIIPI00015361   IPI00028183   IPI01020703   IPI01022982   IPI00030303   
Protein Interaction databases
DIP (DOE-UCLA)Q99471
IntAct (EBI)Q99471
FunCoupENSG00000123349
BioGRIDPFDN5
STRING (EMBL)PFDN5
ZODIACPFDN5
Ontologies - Pathways
QuickGOQ99471
Ontology : AmiGOtranscription corepressor activity  protein binding  nucleus  cytoplasm  regulation of transcription, DNA-templated  protein folding  prefoldin complex  negative regulation of transcription, DNA-templated  unfolded protein binding  retina development in camera-type eye  negative regulation of canonical Wnt signaling pathway  
Ontology : EGO-EBItranscription corepressor activity  protein binding  nucleus  cytoplasm  regulation of transcription, DNA-templated  protein folding  prefoldin complex  negative regulation of transcription, DNA-templated  unfolded protein binding  retina development in camera-type eye  negative regulation of canonical Wnt signaling pathway  
NDEx NetworkPFDN5
Atlas of Cancer Signalling NetworkPFDN5
Wikipedia pathwaysPFDN5
Orthology - Evolution
OrthoDB5204
GeneTree (enSembl)ENSG00000123349
Phylogenetic Trees/Animal Genes : TreeFamPFDN5
HOVERGENQ99471
HOGENOMQ99471
Homologs : HomoloGenePFDN5
Homology/Alignments : Family Browser (UCSC)PFDN5
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPFDN5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PFDN5
dbVarPFDN5
ClinVarPFDN5
1000_GenomesPFDN5 
Exome Variant ServerPFDN5
ExAC (Exome Aggregation Consortium)PFDN5 (select the gene name)
Genetic variants : HAPMAP5204
Genomic Variants (DGV)PFDN5 [DGVbeta]
DECIPHER (Syndromes)12:53689235-53693234  ENSG00000123349
CONAN: Copy Number AnalysisPFDN5 
Mutations
ICGC Data PortalPFDN5 
TCGA Data PortalPFDN5 
Broad Tumor PortalPFDN5
OASIS PortalPFDN5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPFDN5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPFDN5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PFDN5
DgiDB (Drug Gene Interaction Database)PFDN5
DoCM (Curated mutations)PFDN5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PFDN5 (select a term)
intoGenPFDN5
Cancer3DPFDN5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604899   
Orphanet
MedgenPFDN5
Genetic Testing Registry PFDN5
NextProtQ99471 [Medical]
TSGene5204
GENETestsPFDN5
Huge Navigator PFDN5 [HugePedia]
snp3D : Map Gene to Disease5204
BioCentury BCIQPFDN5
ClinGenPFDN5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5204
Chemical/Pharm GKB GenePA33210
Clinical trialPFDN5
Miscellaneous
canSAR (ICR)PFDN5 (select the gene name)
Probes
Litterature
PubMed42 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePFDN5
EVEXPFDN5
GoPubMedPFDN5
iHOPPFDN5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:21:03 CET 2017

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