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PFDN6 (prefoldin subunit 6)

Identity

Alias_namesHKE2
HLA class II region expressed gene KE2
prefoldin 6
Alias_symbol (synonym)KE-2
H2-KE2
PFD6
Other alias
HGNC (Hugo) PFDN6
LocusID (NCBI) 10471
Atlas_Id 47656
Location 6p21.32  [Link to chromosome band 6p21]
Location_base_pair Starts at 33289597 and ends at 33290934 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
HIST2H2BE (1q21.2) / PFDN6 (6p21.32)PFDN6 (6p21.32) / SYNJ2BP-COX16 (14q24.2)PFDN6 (6p21.32) / UHRF2 (9p24.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PFDN6   4926
Cards
Entrez_Gene (NCBI)PFDN6  10471  prefoldin subunit 6
AliasesH2-KE2; HKE2; KE-2; PFD6
GeneCards (Weizmann)PFDN6
Ensembl hg19 (Hinxton)ENSG00000204220 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000204220 [Gene_View]  ENSG00000204220 [Sequence]  chr6:33289597-33290934 [Contig_View]  PFDN6 [Vega]
ICGC DataPortalENSG00000204220
TCGA cBioPortalPFDN6
AceView (NCBI)PFDN6
Genatlas (Paris)PFDN6
WikiGenes10471
SOURCE (Princeton)PFDN6
Genetics Home Reference (NIH)PFDN6
Genomic and cartography
GoldenPath hg38 (UCSC)PFDN6  -     chr6:33289597-33290934 +  6p21.32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PFDN6  -     6p21.32   [Description]    (hg19-Feb_2009)
EnsemblPFDN6 - 6p21.32 [CytoView hg19]  PFDN6 - 6p21.32 [CytoView hg38]
Mapping of homologs : NCBIPFDN6 [Mapview hg19]  PFDN6 [Mapview hg38]
OMIM605660   
Gene and transcription
Genbank (Entrez)AK312150 BC039033 BC059783 BE794658 BM686351
RefSeq transcript (Entrez)NM_001185181 NM_001265595 NM_001265596 NM_014260
RefSeq genomic (Entrez)NC_000006 NT_113891 NT_167245 NT_167247 NT_167248
Consensus coding sequences : CCDS (NCBI)PFDN6
Cluster EST : UnigeneHs.446374 [ NCBI ]
CGAP (NCI)Hs.446374
Alternative Splicing GalleryENSG00000204220
Gene ExpressionPFDN6 [ NCBI-GEO ]   PFDN6 [ EBI - ARRAY_EXPRESS ]   PFDN6 [ SEEK ]   PFDN6 [ MEM ]
Gene Expression Viewer (FireBrowse)PFDN6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10471
GTEX Portal (Tissue expression)PFDN6
Human Protein AtlasENSG00000204220-PFDN6 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO15212   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO15212  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO15212
Splice isoforms : SwissVarO15212
PhosPhoSitePlusO15212
Domains : Interpro (EBI)PFD_beta-like    Prefoldin   
Domain families : Pfam (Sanger)Prefoldin_2 (PF01920)   
Domain families : Pfam (NCBI)pfam01920   
Conserved Domain (NCBI)PFDN6
DMDM Disease mutations10471
Blocks (Seattle)PFDN6
SuperfamilyO15212
Human Protein Atlas [tissue]ENSG00000204220-PFDN6 [tissue]
Peptide AtlasO15212
HPRD16135
IPIIPI00005657   IPI00639894   
Protein Interaction databases
DIP (DOE-UCLA)O15212
IntAct (EBI)O15212
FunCoupENSG00000204220
BioGRIDPFDN6
STRING (EMBL)PFDN6
ZODIACPFDN6
Ontologies - Pathways
QuickGOO15212
Ontology : AmiGOcytoplasm  protein folding  protein folding  prefoldin complex  prefoldin complex  unfolded protein binding  chaperone binding  chaperone binding  chaperone-mediated protein complex assembly  chaperone-mediated protein complex assembly  
Ontology : EGO-EBIcytoplasm  protein folding  protein folding  prefoldin complex  prefoldin complex  unfolded protein binding  chaperone binding  chaperone binding  chaperone-mediated protein complex assembly  chaperone-mediated protein complex assembly  
NDEx NetworkPFDN6
Atlas of Cancer Signalling NetworkPFDN6
Wikipedia pathwaysPFDN6
Orthology - Evolution
OrthoDB10471
GeneTree (enSembl)ENSG00000204220
Phylogenetic Trees/Animal Genes : TreeFamPFDN6
HOVERGENO15212
HOGENOMO15212
Homologs : HomoloGenePFDN6
Homology/Alignments : Family Browser (UCSC)PFDN6
Gene fusions - Rearrangements
Fusion : QuiverPFDN6
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPFDN6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PFDN6
dbVarPFDN6
ClinVarPFDN6
1000_GenomesPFDN6 
Exome Variant ServerPFDN6
ExAC (Exome Aggregation Consortium)ENSG00000204220
GNOMAD BrowserENSG00000204220
Varsome BrowserPFDN6
Genetic variants : HAPMAP10471
Genomic Variants (DGV)PFDN6 [DGVbeta]
DECIPHERPFDN6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPFDN6 
Mutations
ICGC Data PortalPFDN6 
TCGA Data PortalPFDN6 
Broad Tumor PortalPFDN6
OASIS PortalPFDN6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPFDN6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPFDN6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PFDN6
DgiDB (Drug Gene Interaction Database)PFDN6
DoCM (Curated mutations)PFDN6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PFDN6 (select a term)
intoGenPFDN6
Cancer3DPFDN6(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605660   
Orphanet
DisGeNETPFDN6
MedgenPFDN6
Genetic Testing Registry PFDN6
NextProtO15212 [Medical]
TSGene10471
GENETestsPFDN6
Target ValidationPFDN6
Huge Navigator PFDN6 [HugePedia]
snp3D : Map Gene to Disease10471
BioCentury BCIQPFDN6
ClinGenPFDN6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10471
Chemical/Pharm GKB GenePA29304
Clinical trialPFDN6
Miscellaneous
canSAR (ICR)PFDN6 (select the gene name)
Probes
Litterature
PubMed44 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePFDN6
EVEXPFDN6
GoPubMedPFDN6
iHOPPFDN6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 6 11:29:31 CET 2018

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