PFN1 (profilin 1)

Identity

Other names	-
HGNC	PFN1
Location	17p13.2
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	PFN1   8881
Entrez_Gene	PFN1  5216  profilin 1
	Cards
GeneCards	PFN1
Ensembl	PFN1 [Search_View]   ENSG00000108518 [Gene_View]
Genatlas	PFN1
GeneLynx	PFN1
eGenome	PFN1
euGene	5216
	Genomic and cartography
GoldenPath	PFN1  -  17p13.2   chr17:4789692-4792570 -  17p13.2   [Description]    (hg18-March_2006)
Ensembl	PFN1 - 17p13.2 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	PFN1
	Gene and transcription
Genbank	AK312168 [ ENTREZ ]
Genbank	BC002475 [ ENTREZ ]
Genbank	BC006768 [ ENTREZ ]
Genbank	BC013439 [ ENTREZ ]
Genbank	BC015164 [ ENTREZ ]
RefSeq	NM_005022 [ SRS ]    NM_005022 [ ENTREZ ]
RefSeq	AC_000060 [ SRS ]    AC_000060 [ ENTREZ ]
RefSeq	AC_000149 [ SRS ]    AC_000149 [ ENTREZ ]
RefSeq	NC_000017 [ SRS ]    NC_000017 [ ENTREZ ]
RefSeq	NT_010718 [ SRS ]    NT_010718 [ ENTREZ ]
RefSeq	NW_001838403 [ SRS ]    NW_001838403 [ ENTREZ ]
RefSeq	NW_926584 [ SRS ]    NW_926584 [ ENTREZ ]
AceView	PFN1 AceView - NCBI
Unigene	Hs.494691 [ SRS ]    Hs.494691 [ NCBI ]     HS494691 [ spliceNest ]
Fast-db	1846 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P07737 [ SRS]    P07737 [ EXPASY ]     P07737 [ INTERPRO ]     P07737 [ UNIPROT ]
Prosite	PS00414 PROFILIN [ SRS ]    PS00414 PROFILIN [ Expasy ]
Interpro	IPR002097 Profilin [ SRS ]    IPR002097 Profilin [ EBI ]
Interpro	IPR005454 Profilin_mammal [ SRS ]    IPR005454 Profilin_mammal [ EBI ]
CluSTr	P07737
Pfam	PF00235 Profilin [ SRS ]    PF00235 Profilin [ Sanger ]    pfam00235 [ NCBI-CDD ]
Smart	SM00392 PROF [EMBL]
Blocks	P07737
PDB	1AWI [ SRS ]    1AWI [ PdbSum ],   1AWI [ IMB ]   1AWI [ RSDB ]
PDB	1CF0 [ SRS ]    1CF0 [ PdbSum ],   1CF0 [ IMB ]   1CF0 [ RSDB ]
PDB	1CJF [ SRS ]    1CJF [ PdbSum ],   1CJF [ IMB ]   1CJF [ RSDB ]
PDB	1FIK [ SRS ]    1FIK [ PdbSum ],   1FIK [ IMB ]   1FIK [ RSDB ]
PDB	1FIL [ SRS ]    1FIL [ PdbSum ],   1FIL [ IMB ]   1FIL [ RSDB ]
PDB	1PFL [ SRS ]    1PFL [ PdbSum ],   1PFL [ IMB ]   1PFL [ RSDB ]
PDB	2PAV [ SRS ]    2PAV [ PdbSum ],   2PAV [ IMB ]   2PAV [ RSDB ]
PDB	2PBD [ SRS ]    2PBD [ PdbSum ],   2PBD [ IMB ]   2PBD [ RSDB ]
HPRD	01452
	Protein Interaction databases
DIP	P07737
IntAct	P07737
	Polymorphism : SNP, mutations, diseases
OMIM	176610    [ map ]
GENECLINICS	176610
SNP	PFN1 [dbSNP-NCBI]
SNP	NM_005022 [SNP-NCI]
SNP	PFN1 [GeneSNPs - Utah]  PFN1] [HGBASE - SRS]
HAPMAP	PFN1 [HAPMAP]
HGMD	PFN1
	General knowledge
Family Browser	PFN1 [UCSC Family Browser]
SOURCE	NM_005022
SMD	Hs.494691
SAGE	Hs.494691
GO	neural tube closure [Amigo]  neural tube closure
GO	actin binding [Amigo]  actin binding
GO	protein binding [Amigo]  protein binding
GO	nucleus [Amigo]  nucleus
GO	cytoplasm [Amigo]  cytoplasm
GO	regulation of transcription from RNA polymerase II promoter [Amigo]  regulation of transcription from RNA polymerase II promoter
GO	cytoskeleton organization and biogenesis [Amigo]  cytoskeleton organization and biogenesis
GO	actin cytoskeleton [Amigo]  actin cytoskeleton
GO	actin cytoskeleton organization and biogenesis [Amigo]  actin cytoskeleton organization and biogenesis
BIOCARTA	Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia    [Genes]
BIOCARTA	Rho cell motility signaling pathway    [Genes]
KEGG	Regulation of actin cytoskeleton
PubGene	PFN1
TreeFam	PFN1
CTD	5216 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	PFN1 Related clones (RZPD - Berlin)
	PubMed
PubMed	45 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 20:24:27 2008