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PFN4 (profilin family member 4)

Identity

Alias_namesprofilin family, member 4
Other alias-
HGNC (Hugo) PFN4
LocusID (NCBI) 375189
Atlas_Id 71850
Location 2p23.3  [Link to chromosome band 2p23]
Location_base_pair Starts at 24114809 and ends at 24123477 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PFN4   31103
Cards
Entrez_Gene (NCBI)PFN4  375189  profilin family member 4
Aliases
GeneCards (Weizmann)PFN4
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr2:24114809-24123477 [Contig_View]  PFN4 [Vega]
TCGA cBioPortalPFN4
AceView (NCBI)PFN4
Genatlas (Paris)PFN4
WikiGenes375189
SOURCE (Princeton)PFN4
Genetics Home Reference (NIH)PFN4
Genomic and cartography
GoldenPath hg38 (UCSC)PFN4  -     chr2:24114809-24123477 -  2p23.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PFN4  -     2p23.3   [Description]    (hg19-Feb_2009)
EnsemblPFN4 - 2p23.3 [CytoView hg19]  PFN4 - 2p23.3 [CytoView hg38]
Mapping of homologs : NCBIPFN4 [Mapview hg19]  PFN4 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK292601 BC029523 BC043236
RefSeq transcript (Entrez)NM_199346
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PFN4
Cluster EST : UnigeneHs.442718 [ NCBI ]
CGAP (NCI)Hs.442718
Gene ExpressionPFN4 [ NCBI-GEO ]   PFN4 [ EBI - ARRAY_EXPRESS ]   PFN4 [ SEEK ]   PFN4 [ MEM ]
Gene Expression Viewer (FireBrowse)PFN4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)375189
GTEX Portal (Tissue expression)PFN4
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NHR9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NHR9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NHR9
Splice isoforms : SwissVarQ8NHR9
PhosPhoSitePlusQ8NHR9
Domains : Interpro (EBI)PFN   
Domain families : Pfam (Sanger)Profilin (PF00235)   
Domain families : Pfam (NCBI)pfam00235   
Domain families : Smart (EMBL)PROF (SM00392)  
Conserved Domain (NCBI)PFN4
DMDM Disease mutations375189
Blocks (Seattle)PFN4
SuperfamilyQ8NHR9
Peptide AtlasQ8NHR9
HPRD15120
IPIIPI00169306   IPI00893364   
Protein Interaction databases
DIP (DOE-UCLA)Q8NHR9
IntAct (EBI)Q8NHR9
BioGRIDPFN4
STRING (EMBL)PFN4
ZODIACPFN4
Ontologies - Pathways
QuickGOQ8NHR9
Ontology : AmiGOactin monomer binding  cell cortex  lipid binding  actin cytoskeleton  sequestering of actin monomers  
Ontology : EGO-EBIactin monomer binding  cell cortex  lipid binding  actin cytoskeleton  sequestering of actin monomers  
Pathways : KEGGRap1 signaling pathway    Regulation of actin cytoskeleton    Shigellosis    Salmonella infection   
NDEx NetworkPFN4
Atlas of Cancer Signalling NetworkPFN4
Wikipedia pathwaysPFN4
Orthology - Evolution
OrthoDB375189
Phylogenetic Trees/Animal Genes : TreeFamPFN4
HOVERGENQ8NHR9
HOGENOMQ8NHR9
Homologs : HomoloGenePFN4
Homology/Alignments : Family Browser (UCSC)PFN4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPFN4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PFN4
dbVarPFN4
ClinVarPFN4
1000_GenomesPFN4 
Exome Variant ServerPFN4
ExAC (Exome Aggregation Consortium)PFN4 (select the gene name)
Genetic variants : HAPMAP375189
Genomic Variants (DGV)PFN4 [DGVbeta]
DECIPHERPFN4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPFN4 
Mutations
ICGC Data PortalPFN4 
TCGA Data PortalPFN4 
Broad Tumor PortalPFN4
OASIS PortalPFN4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPFN4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPFN4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PFN4
DgiDB (Drug Gene Interaction Database)PFN4
DoCM (Curated mutations)PFN4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PFN4 (select a term)
intoGenPFN4
Cancer3DPFN4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenPFN4
Genetic Testing Registry PFN4
NextProtQ8NHR9 [Medical]
TSGene375189
GENETestsPFN4
Target ValidationPFN4
Huge Navigator PFN4 [HugePedia]
snp3D : Map Gene to Disease375189
BioCentury BCIQPFN4
ClinGenPFN4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD375189
Chemical/Pharm GKB GenePA134919643
Clinical trialPFN4
Miscellaneous
canSAR (ICR)PFN4 (select the gene name)
Probes
Litterature
PubMed4 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePFN4
EVEXPFN4
GoPubMedPFN4
iHOPPFN4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:36:07 CEST 2017

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