Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

PGAP3 (post-GPI attachment to proteins 3)

Identity

Alias_namesPERLD1
per1-like domain containing 1
Alias_symbol (synonym)MGC9753
CAB2
PP1498
PER1
Other aliasAGLA546
hCOS16
HGNC (Hugo) PGAP3
LocusID (NCBI) 93210
Atlas_Id 50943
Location 17q12  [Link to chromosome band 17q12]
Location_base_pair Starts at 39671122 and ends at 39688070 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ETV6 (12p13.2) / PGAP3 (17q12)GRB7 (17q12) / PGAP3 (17q12)PGAP3 (17q12) / ETV6 (12p13.2)
PGAP3 (17q12) / GSDMB (17q12)PGAP3 (17q12) / PPM1D (17q23.2)PGAP3 (17q12) / STARD3 (17q12)
RARA (17q21.2) / PGAP3 (17q12)WDR70 (5p13.2) / PGAP3 (17q12)GRB7 17q12 / PGAP3 17q12
PGAP3 17q12 / STARD3 17q12RARA 17q21.2 / PGAP3 17q12WDR70 5p13.2 / PGAP3 17q12

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PGAP3   23719
Cards
Entrez_Gene (NCBI)PGAP3  93210  post-GPI attachment to proteins 3
AliasesAGLA546; CAB2; PERLD1; PP1498; 
hCOS16
GeneCards (Weizmann)PGAP3
Ensembl hg19 (Hinxton)ENSG00000161395 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000161395 [Gene_View]  chr17:39671122-39688070 [Contig_View]  PGAP3 [Vega]
ICGC DataPortalENSG00000161395
TCGA cBioPortalPGAP3
AceView (NCBI)PGAP3
Genatlas (Paris)PGAP3
WikiGenes93210
SOURCE (Princeton)PGAP3
Genetics Home Reference (NIH)PGAP3
Genomic and cartography
GoldenPath hg38 (UCSC)PGAP3  -     chr17:39671122-39688070 -  17q12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PGAP3  -     17q12   [Description]    (hg19-Feb_2009)
EnsemblPGAP3 - 17q12 [CytoView hg19]  PGAP3 - 17q12 [CytoView hg38]
Mapping of homologs : NCBIPGAP3 [Mapview hg19]  PGAP3 [Mapview hg38]
OMIM611801   615716   
Gene and transcription
Genbank (Entrez)AB088396 AF217980 AK057911 AK075473 AK075474
RefSeq transcript (Entrez)NM_001291726 NM_001291728 NM_001291730 NM_001291732 NM_001291733 NM_033419
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PGAP3
Cluster EST : UnigeneHs.462971 [ NCBI ]
CGAP (NCI)Hs.462971
Alternative Splicing GalleryENSG00000161395
Gene ExpressionPGAP3 [ NCBI-GEO ]   PGAP3 [ EBI - ARRAY_EXPRESS ]   PGAP3 [ SEEK ]   PGAP3 [ MEM ]
Gene Expression Viewer (FireBrowse)PGAP3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)93210
GTEX Portal (Tissue expression)PGAP3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96FM1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96FM1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96FM1
Splice isoforms : SwissVarQ96FM1
PhosPhoSitePlusQ96FM1
Domains : Interpro (EBI)Per1   
Domain families : Pfam (Sanger)Per1 (PF04080)   
Domain families : Pfam (NCBI)pfam04080   
Conserved Domain (NCBI)PGAP3
DMDM Disease mutations93210
Blocks (Seattle)PGAP3
SuperfamilyQ96FM1
Human Protein AtlasENSG00000161395
Peptide AtlasQ96FM1
HPRD15118
IPIIPI00420005   IPI00742797   IPI00908541   IPI01013171   IPI00387114   
Protein Interaction databases
DIP (DOE-UCLA)Q96FM1
IntAct (EBI)Q96FM1
FunCoupENSG00000161395
BioGRIDPGAP3
STRING (EMBL)PGAP3
ZODIACPGAP3
Ontologies - Pathways
QuickGOQ96FM1
Ontology : AmiGOGolgi membrane  GPI anchor metabolic process  GPI anchor biosynthetic process  integral component of membrane  hydrolase activity, acting on ester bonds  intrinsic component of endoplasmic reticulum membrane  
Ontology : EGO-EBIGolgi membrane  GPI anchor metabolic process  GPI anchor biosynthetic process  integral component of membrane  hydrolase activity, acting on ester bonds  intrinsic component of endoplasmic reticulum membrane  
NDEx NetworkPGAP3
Atlas of Cancer Signalling NetworkPGAP3
Wikipedia pathwaysPGAP3
Orthology - Evolution
OrthoDB93210
GeneTree (enSembl)ENSG00000161395
Phylogenetic Trees/Animal Genes : TreeFamPGAP3
HOVERGENQ96FM1
HOGENOMQ96FM1
Homologs : HomoloGenePGAP3
Homology/Alignments : Family Browser (UCSC)PGAP3
Gene fusions - Rearrangements
Fusion : MitelmanPGAP3/PPM1D [17q12/17q23.2]  
Fusion : MitelmanRARA/PGAP3 [17q21.2/17q12]  [t(17;17)(q12;q21)]  
Fusion : MitelmanWDR70/PGAP3 [5p13.2/17q12]  [t(5;17)(p13;q12)]  
Fusion: TCGAGRB7 17q12 PGAP3 17q12 BRCA
Fusion: TCGAPGAP3 17q12 STARD3 17q12 BLCA
Fusion: TCGARARA 17q21.2 PGAP3 17q12 BRCA
Fusion: TCGAWDR70 5p13.2 PGAP3 17q12 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPGAP3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PGAP3
dbVarPGAP3
ClinVarPGAP3
1000_GenomesPGAP3 
Exome Variant ServerPGAP3
ExAC (Exome Aggregation Consortium)PGAP3 (select the gene name)
Genetic variants : HAPMAP93210
Genomic Variants (DGV)PGAP3 [DGVbeta]
DECIPHERPGAP3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPGAP3 
Mutations
ICGC Data PortalPGAP3 
TCGA Data PortalPGAP3 
Broad Tumor PortalPGAP3
OASIS PortalPGAP3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPGAP3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPGAP3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PGAP3
DgiDB (Drug Gene Interaction Database)PGAP3
DoCM (Curated mutations)PGAP3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PGAP3 (select a term)
intoGenPGAP3
Cancer3DPGAP3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611801    615716   
Orphanet19518   
MedgenPGAP3
Genetic Testing Registry PGAP3
NextProtQ96FM1 [Medical]
TSGene93210
GENETestsPGAP3
Target ValidationPGAP3
Huge Navigator PGAP3 [HugePedia]
snp3D : Map Gene to Disease93210
BioCentury BCIQPGAP3
ClinGenPGAP3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD93210
Chemical/Pharm GKB GenePA165432310
Clinical trialPGAP3
Miscellaneous
canSAR (ICR)PGAP3 (select the gene name)
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePGAP3
EVEXPGAP3
GoPubMedPGAP3
iHOPPGAP3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas oŠ Gen%tias and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 25 19:24:30 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.