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PGC (progastricsin (pepsinogen C))

Identity

Other namesPEPC
PGII
HGNC (Hugo) PGC
LocusID (NCBI) 5225
Atlas_Id 43776
Location 6p21.1
Location_base_pair Starts at 41708576 and ends at 41715139 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)PGC   8890
Cards
Entrez_Gene (NCBI)PGC  5225  progastricsin (pepsinogen C)
GeneCards (Weizmann)PGC
Ensembl hg19 (Hinxton)ENSG00000096088 [Gene_View]  chr6:41708576-41715139 [Contig_View]  PGC [Vega]
Ensembl hg38 (Hinxton)ENSG00000096088 [Gene_View]  chr6:41708576-41715139 [Contig_View]  PGC [Vega]
ICGC DataPortalENSG00000096088
TCGA cBioPortalPGC
AceView (NCBI)PGC
Genatlas (Paris)PGC
WikiGenes5225
SOURCE (Princeton)PGC
Genomic and cartography
GoldenPath hg19 (UCSC)PGC  -     chr6:41708576-41715139 -  6p21.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)PGC  -     6p21.1   [Description]    (hg38-Dec_2013)
EnsemblPGC - 6p21.1 [CytoView hg19]  PGC - 6p21.1 [CytoView hg38]
Mapping of homologs : NCBIPGC [Mapview hg19]  PGC [Mapview hg38]
OMIM169740   
Gene and transcription
Genbank (Entrez)AK223274 AK301298 AK301325 BC042578 BC073740
RefSeq transcript (Entrez)NM_001166424 NM_002630
RefSeq genomic (Entrez)NC_000006 NC_018917 NT_007592 NW_004929326
Consensus coding sequences : CCDS (NCBI)PGC
Cluster EST : UnigeneHs.1867 [ NCBI ]
CGAP (NCI)Hs.1867
Alternative Splicing : Fast-db (Paris)GSHG0026605
Alternative Splicing GalleryENSG00000096088
Gene ExpressionPGC [ NCBI-GEO ]     PGC [ SEEK ]   PGC [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP20142 (Uniprot)
NextProtP20142  [Medical]
With graphics : InterProP20142
Splice isoforms : SwissVarP20142 (Swissvar)
Catalytic activity : Enzyme3.4.23.3 [ Enzyme-Expasy ]   3.4.23.33.4.23.3 [ IntEnz-EBI ]   3.4.23.3 [ BRENDA ]   3.4.23.3 [ KEGG ]   
Domaine pattern : Prosite (Expaxy)ASP_PROTEASE (PS00141)   
Domains : Interpro (EBI)Aspartic_peptidase    Aspartic_peptidase_AS    Aspartic_peptidase_N    Peptidase_aspartic_dom   
Related proteins : CluSTrP20142
Domain families : Pfam (Sanger)A1_Propeptide (PF07966)    Asp (PF00026)   
Domain families : Pfam (NCBI)pfam07966    pfam00026   
DMDM Disease mutations5225
Blocks (Seattle)P20142
PDB (SRS)1AVF    1HTR   
PDB (PDBSum)1AVF    1HTR   
PDB (IMB)1AVF    1HTR   
PDB (RSDB)1AVF    1HTR   
Human Protein AtlasENSG00000096088
Peptide AtlasP20142
HPRD01357
IPIIPI00022213   IPI00383359   IPI00910787   IPI00607684   IPI00792533   
Protein Interaction databases
DIP (DOE-UCLA)P20142
IntAct (EBI)P20142
FunCoupENSG00000096088
BioGRIDPGC
IntegromeDBPGC
STRING (EMBL)PGC
Ontologies - Pathways
QuickGOP20142
Ontology : AmiGOaspartic-type endopeptidase activity  extracellular space  proteolysis  digestion  extracellular exosome  
Ontology : EGO-EBIaspartic-type endopeptidase activity  extracellular space  proteolysis  digestion  extracellular exosome  
Protein Interaction DatabasePGC
DoCM (Curated mutations)PGC
Wikipedia pathwaysPGC
Gene fusion - Rearrangements
Gene fusion: TCGA
Polymorphisms : SNP, variants
NCBI Variation ViewerPGC [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PGC
dbVarPGC
ClinVarPGC
1000_GenomesPGC 
Exome Variant ServerPGC
SNP (GeneSNP Utah)PGC
SNP : HGBasePGC
Genetic variants : HAPMAPPGC
Genomic Variants (DGV)PGC [DGVbeta]
Mutations
ICGC Data PortalPGC 
TCGA Data PortalPGC 
Tumor PortalPGC
Somatic Mutations in Cancer : COSMICPGC 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)6:41708576-41715139
CONAN: Copy Number AnalysisPGC 
Mutations and Diseases : HGMDPGC
OMIM169740   
MedgenPGC
NextProtP20142 [Medical]
GENETestsPGC
Disease Genetic AssociationPGC
Huge Navigator PGC [HugePedia]  PGC [HugeCancerGEM]
snp3D : Map Gene to Disease5225
DGIdb (Drug Gene Interaction db)PGC
General knowledge
Homologs : HomoloGenePGC
Homology/Alignments : Family Browser (UCSC)PGC
Phylogenetic Trees/Animal Genes : TreeFamPGC
Chemical/Protein Interactions : CTD5225
Chemical/Pharm GKB GenePA33228
Clinical trialPGC
Cancer Resource (Charite)ENSG00000096088
Other databases
Probes
Litterature
PubMed65 Pubmed reference(s) in Entrez
CoreMinePGC
GoPubMedPGC
iHOPPGC
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated02-2015Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Apr 13 14:58:53 CEST 2015

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