Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5229
MIM: 602031
HGNC: 8895
Ensembl: ENSG00000164219
Variants:
dbSNP: 5229
ClinVar: 5229
TCGA: ENSG00000164219
COSMIC: PGGT1B
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000164219 | ENST00000379615 | P53609 |
| ENSG00000164219 | ENST00000419445 | P53609 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33548109 | 2021 | The diagnostic significance of PGGT1B in psoriasis. | 0 |
| 33548109 | 2021 | The diagnostic significance of PGGT1B in psoriasis. | 0 |
| 23475391 | 2013 | Geranylgeranyltransferase I regulates HIF-1α promoting glioblastoma cell migration and invasion. | 3 |
| 23475391 | 2013 | Geranylgeranyltransferase I regulates HIF-1α promoting glioblastoma cell migration and invasion. | 3 |
| 22160308 | 2012 | Geranylgeranyl transferase 1 modulates autophagy and apoptosis in human airway smooth muscle. | 29 |
| 22160308 | 2012 | Geranylgeranyl transferase 1 modulates autophagy and apoptosis in human airway smooth muscle. | 29 |
| 20403997 | 2010 | Genetic variation in 3-hydroxy-3-methylglutaryl CoA reductase modifies the chemopreventive activity of statins for colorectal cancer. | 35 |
| 20446922 | 2010 | Inhibition of GGTase-I and FTase disrupts cytoskeletal organization of human PC-3 prostate cancer cells. | 8 |
| 20403997 | 2010 | Genetic variation in 3-hydroxy-3-methylglutaryl CoA reductase modifies the chemopreventive activity of statins for colorectal cancer. | 35 |
| 20446922 | 2010 | Inhibition of GGTase-I and FTase disrupts cytoskeletal organization of human PC-3 prostate cancer cells. | 8 |
| 19667218 | 2009 | Genome-wide scan of 500,000 single-nucleotide polymorphisms among responders and nonresponders to interferon beta therapy in multiple sclerosis. | 28 |
| 19667218 | 2009 | Genome-wide scan of 500,000 single-nucleotide polymorphisms among responders and nonresponders to interferon beta therapy in multiple sclerosis. | 28 |
| 15451670 | 2004 | Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity. | 112 |
| 15451670 | 2004 | Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity. | 112 |
| 14598891 | 2003 | Selective inhibition of cancer cell invasion by a geranylgeranyltransferase-I inhibitor. | 19 |
Citation
Dessen P
PGGT1B (protein geranylgeranyltransferase type I subunit beta)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43928/pggt1b
