Atlas of Genetics and Cytogenetics in Oncology and Haematology


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PGK2 (phosphoglycerate kinase 2)

Identity

Other aliasHEL-S-272
PGKB
PGKPS
dJ417L20.2
HGNC (Hugo) PGK2
LocusID (NCBI) 5232
Atlas_Id 57534
Location 6p12.3  [Link to chromosome band 6p12]
Location_base_pair Starts at 49785651 and ends at 49787340 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PGK2   8898
Cards
Entrez_Gene (NCBI)PGK2  5232  phosphoglycerate kinase 2
AliasesHEL-S-272; PGKB; PGKPS; dJ417L20.2
GeneCards (Weizmann)PGK2
Ensembl hg19 (Hinxton)ENSG00000170950 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000170950 [Gene_View]  ENSG00000170950 [Sequence]  chr6:49785651-49787340 [Contig_View]  PGK2 [Vega]
ICGC DataPortalENSG00000170950
TCGA cBioPortalPGK2
AceView (NCBI)PGK2
Genatlas (Paris)PGK2
WikiGenes5232
SOURCE (Princeton)PGK2
Genetics Home Reference (NIH)PGK2
Genomic and cartography
GoldenPath hg38 (UCSC)PGK2  -     chr6:49785651-49787340 -  6p12.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PGK2  -     6p12.3   [Description]    (hg19-Feb_2009)
EnsemblPGK2 - 6p12.3 [CytoView hg19]  PGK2 - 6p12.3 [CytoView hg38]
Mapping of homologs : NCBIPGK2 [Mapview hg19]  PGK2 [Mapview hg38]
OMIM172270   
Gene and transcription
Genbank (Entrez)AK312770 BC038843 DB043284 FJ224296 HM005452
RefSeq transcript (Entrez)NM_138733
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PGK2
Cluster EST : UnigeneHs.367727 [ NCBI ]
CGAP (NCI)Hs.367727
Alternative Splicing GalleryENSG00000170950
Gene ExpressionPGK2 [ NCBI-GEO ]   PGK2 [ EBI - ARRAY_EXPRESS ]   PGK2 [ SEEK ]   PGK2 [ MEM ]
Gene Expression Viewer (FireBrowse)PGK2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5232
GTEX Portal (Tissue expression)PGK2
Human Protein AtlasENSG00000170950-PGK2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP07205   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP07205  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP07205
Splice isoforms : SwissVarP07205
Catalytic activity : Enzyme2.7.2.3 [ Enzyme-Expasy ]   2.7.2.32.7.2.3 [ IntEnz-EBI ]   2.7.2.3 [ BRENDA ]   2.7.2.3 [ KEGG ]   
PhosPhoSitePlusP07205
Domaine pattern : Prosite (Expaxy)PGLYCERATE_KINASE (PS00111)   
Domains : Interpro (EBI)Phosphoglycerate_kinase    Phosphoglycerate_kinase_CS    Phosphoglycerate_kinase_N    Phosphoglycerate_kinase_sf   
Domain families : Pfam (Sanger)PGK (PF00162)   
Domain families : Pfam (NCBI)pfam00162   
Conserved Domain (NCBI)PGK2
DMDM Disease mutations5232
Blocks (Seattle)PGK2
SuperfamilyP07205
Human Protein Atlas [tissue]ENSG00000170950-PGK2 [tissue]
Peptide AtlasP07205
IPIIPI00219568   
Protein Interaction databases
DIP (DOE-UCLA)P07205
IntAct (EBI)P07205
FunCoupENSG00000170950
BioGRIDPGK2
STRING (EMBL)PGK2
ZODIACPGK2
Ontologies - Pathways
QuickGOP07205
Ontology : AmiGOphosphoglycerate kinase activity  phosphoglycerate kinase activity  phosphoglycerate kinase activity  ATP binding  ATP binding  nucleus  cytosol  gluconeogenesis  glycolytic process  glycolytic process  glycolytic process  chemical synaptic transmission  myoblast fusion  somatic muscle development  phosphorylation  phosphorylation  flagellated sperm motility  sperm fibrous sheath  ADP binding  muscle cell cellular homeostasis  extracellular exosome  
Ontology : EGO-EBIphosphoglycerate kinase activity  phosphoglycerate kinase activity  phosphoglycerate kinase activity  ATP binding  ATP binding  nucleus  cytosol  gluconeogenesis  glycolytic process  glycolytic process  glycolytic process  chemical synaptic transmission  myoblast fusion  somatic muscle development  phosphorylation  phosphorylation  flagellated sperm motility  sperm fibrous sheath  ADP binding  muscle cell cellular homeostasis  extracellular exosome  
Pathways : KEGGGlycolysis / Gluconeogenesis   
NDEx NetworkPGK2
Atlas of Cancer Signalling NetworkPGK2
Wikipedia pathwaysPGK2
Orthology - Evolution
OrthoDB5232
GeneTree (enSembl)ENSG00000170950
Phylogenetic Trees/Animal Genes : TreeFamPGK2
HOVERGENP07205
HOGENOMP07205
Homologs : HomoloGenePGK2
Homology/Alignments : Family Browser (UCSC)PGK2
Gene fusions - Rearrangements
Fusion : QuiverPGK2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPGK2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PGK2
dbVarPGK2
ClinVarPGK2
1000_GenomesPGK2 
Exome Variant ServerPGK2
ExAC (Exome Aggregation Consortium)ENSG00000170950
GNOMAD BrowserENSG00000170950
Varsome BrowserPGK2
Genetic variants : HAPMAP5232
Genomic Variants (DGV)PGK2 [DGVbeta]
DECIPHERPGK2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPGK2 
Mutations
ICGC Data PortalPGK2 
TCGA Data PortalPGK2 
Broad Tumor PortalPGK2
OASIS PortalPGK2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPGK2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPGK2
BioMutasearch PGK2
DgiDB (Drug Gene Interaction Database)PGK2
DoCM (Curated mutations)PGK2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PGK2 (select a term)
intoGenPGK2
Cancer3DPGK2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM172270   
Orphanet
DisGeNETPGK2
MedgenPGK2
Genetic Testing Registry PGK2
NextProtP07205 [Medical]
TSGene5232
GENETestsPGK2
Target ValidationPGK2
Huge Navigator PGK2 [HugePedia]
snp3D : Map Gene to Disease5232
BioCentury BCIQPGK2
ClinGenPGK2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5232
Chemical/Pharm GKB GenePA33237
Clinical trialPGK2
Miscellaneous
canSAR (ICR)PGK2 (select the gene name)
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePGK2
EVEXPGK2
GoPubMedPGK2
iHOPPGK2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 11:29:37 CET 2018

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