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PGLS (6-phosphogluconolactonase)

Identity

Alias_symbol (synonym)6PGL
Other aliasHEL-S-304
HGNC (Hugo) PGLS
LocusID (NCBI) 25796
Atlas_Id 71863
Location 19p13.11  [Link to chromosome band 19p13]
Location_base_pair Starts at 17511623 and ends at 17521288 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PGLS   8903
Cards
Entrez_Gene (NCBI)PGLS  25796  6-phosphogluconolactonase
Aliases6PGL; HEL-S-304
GeneCards (Weizmann)PGLS
Ensembl hg19 (Hinxton)ENSG00000130313 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000130313 [Gene_View]  chr19:17511623-17521288 [Contig_View]  PGLS [Vega]
ICGC DataPortalENSG00000130313
TCGA cBioPortalPGLS
AceView (NCBI)PGLS
Genatlas (Paris)PGLS
WikiGenes25796
SOURCE (Princeton)PGLS
Genetics Home Reference (NIH)PGLS
Genomic and cartography
GoldenPath hg38 (UCSC)PGLS  -     chr19:17511623-17521288 +  19p13.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PGLS  -     19p13.11   [Description]    (hg19-Feb_2009)
EnsemblPGLS - 19p13.11 [CytoView hg19]  PGLS - 19p13.11 [CytoView hg38]
Mapping of homologs : NCBIPGLS [Mapview hg19]  PGLS [Mapview hg38]
OMIM604951   
Gene and transcription
Genbank (Entrez)AF091091 AJ243972 BC014006 BC017706 BG764228
RefSeq transcript (Entrez)NM_012088
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PGLS
Cluster EST : UnigeneHs.466165 [ NCBI ]
CGAP (NCI)Hs.466165
Alternative Splicing GalleryENSG00000130313
Gene ExpressionPGLS [ NCBI-GEO ]   PGLS [ EBI - ARRAY_EXPRESS ]   PGLS [ SEEK ]   PGLS [ MEM ]
Gene Expression Viewer (FireBrowse)PGLS [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)25796
GTEX Portal (Tissue expression)PGLS
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95336   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95336  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95336
Splice isoforms : SwissVarO95336
PhosPhoSitePlusO95336
Domains : Interpro (EBI)6-phosphogluconolactonase_DevB    Glc/Gal-6P_isomerase   
Domain families : Pfam (Sanger)Glucosamine_iso (PF01182)   
Domain families : Pfam (NCBI)pfam01182   
Conserved Domain (NCBI)PGLS
DMDM Disease mutations25796
Blocks (Seattle)PGLS
SuperfamilyO95336
Human Protein AtlasENSG00000130313
Peptide AtlasO95336
HPRD12001
IPIIPI00029997   
Protein Interaction databases
DIP (DOE-UCLA)O95336
IntAct (EBI)O95336
FunCoupENSG00000130313
BioGRIDPGLS
STRING (EMBL)PGLS
ZODIACPGLS
Ontologies - Pathways
QuickGOO95336
Ontology : AmiGOprotein binding  cytoplasm  cytosol  carbohydrate metabolic process  pentose-phosphate shunt  pentose-phosphate shunt  pentose-phosphate shunt, oxidative branch  6-phosphogluconolactonase activity  6-phosphogluconolactonase activity  extracellular exosome  
Ontology : EGO-EBIprotein binding  cytoplasm  cytosol  carbohydrate metabolic process  pentose-phosphate shunt  pentose-phosphate shunt  pentose-phosphate shunt, oxidative branch  6-phosphogluconolactonase activity  6-phosphogluconolactonase activity  extracellular exosome  
Pathways : KEGGPentose phosphate pathway   
NDEx NetworkPGLS
Atlas of Cancer Signalling NetworkPGLS
Wikipedia pathwaysPGLS
Orthology - Evolution
OrthoDB25796
GeneTree (enSembl)ENSG00000130313
Phylogenetic Trees/Animal Genes : TreeFamPGLS
HOVERGENO95336
HOGENOMO95336
Homologs : HomoloGenePGLS
Homology/Alignments : Family Browser (UCSC)PGLS
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPGLS [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PGLS
dbVarPGLS
ClinVarPGLS
1000_GenomesPGLS 
Exome Variant ServerPGLS
ExAC (Exome Aggregation Consortium)PGLS (select the gene name)
Genetic variants : HAPMAP25796
Genomic Variants (DGV)PGLS [DGVbeta]
DECIPHERPGLS [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPGLS 
Mutations
ICGC Data PortalPGLS 
TCGA Data PortalPGLS 
Broad Tumor PortalPGLS
OASIS PortalPGLS [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPGLS  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPGLS
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PGLS
DgiDB (Drug Gene Interaction Database)PGLS
DoCM (Curated mutations)PGLS (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PGLS (select a term)
intoGenPGLS
Cancer3DPGLS(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604951   
Orphanet
MedgenPGLS
Genetic Testing Registry PGLS
NextProtO95336 [Medical]
TSGene25796
GENETestsPGLS
Target ValidationPGLS
Huge Navigator PGLS [HugePedia]
snp3D : Map Gene to Disease25796
BioCentury BCIQPGLS
ClinGenPGLS
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD25796
Chemical/Pharm GKB GenePA33240
Clinical trialPGLS
Miscellaneous
canSAR (ICR)PGLS (select the gene name)
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePGLS
EVEXPGLS
GoPubMedPGLS
iHOPPGLS
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Sep 18 13:34:24 CEST 2017

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