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PGLYRP2 (peptidoglycan recognition protein 2)

Identity

Alias_symbol (synonym)PGRP-L
PGLYRPL
TAGL-like
tagL
tagL-alpha
tagl-beta
PGRPL
Other aliasHMFT0141
HGNC (Hugo) PGLYRP2
LocusID (NCBI) 114770
Atlas_Id 71864
Location 19p13.12  [Link to chromosome band 19p13]
Location_base_pair Starts at 15468646 and ends at 15479504 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PGLYRP2   30013
Cards
Entrez_Gene (NCBI)PGLYRP2  114770  peptidoglycan recognition protein 2
AliasesHMFT0141; PGLYRPL; PGRP-L; PGRPL; 
TAGL-like; tagL; tagL-alpha; tagl-beta
GeneCards (Weizmann)PGLYRP2
Ensembl hg19 (Hinxton)ENSG00000161031 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000161031 [Gene_View]  chr19:15468646-15479504 [Contig_View]  PGLYRP2 [Vega]
ICGC DataPortalENSG00000161031
TCGA cBioPortalPGLYRP2
AceView (NCBI)PGLYRP2
Genatlas (Paris)PGLYRP2
WikiGenes114770
SOURCE (Princeton)PGLYRP2
Genetics Home Reference (NIH)PGLYRP2
Genomic and cartography
GoldenPath hg38 (UCSC)PGLYRP2  -     chr19:15468646-15479504 -  19p13.12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PGLYRP2  -     19p13.12   [Description]    (hg19-Feb_2009)
EnsemblPGLYRP2 - 19p13.12 [CytoView hg19]  PGLYRP2 - 19p13.12 [CytoView hg38]
Mapping of homologs : NCBIPGLYRP2 [Mapview hg19]  PGLYRP2 [Mapview hg38]
OMIM608199   
Gene and transcription
Genbank (Entrez)AB073610 AF384856 AK055882 AK289415 AK292292
RefSeq transcript (Entrez)NM_052890
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PGLYRP2
Cluster EST : UnigeneHs.282244 [ NCBI ]
CGAP (NCI)Hs.282244
Alternative Splicing GalleryENSG00000161031
Gene ExpressionPGLYRP2 [ NCBI-GEO ]   PGLYRP2 [ EBI - ARRAY_EXPRESS ]   PGLYRP2 [ SEEK ]   PGLYRP2 [ MEM ]
Gene Expression Viewer (FireBrowse)PGLYRP2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)114770
GTEX Portal (Tissue expression)PGLYRP2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96PD5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96PD5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96PD5
Splice isoforms : SwissVarQ96PD5
Catalytic activity : Enzyme3.5.1.28 [ Enzyme-Expasy ]   3.5.1.283.5.1.28 [ IntEnz-EBI ]   3.5.1.28 [ BRENDA ]   3.5.1.28 [ KEGG ]   
PhosPhoSitePlusQ96PD5
Domains : Interpro (EBI)Amidase_domain    PGRP    PGRP_domain_met/bac   
Domain families : Pfam (Sanger)Amidase_2 (PF01510)   
Domain families : Pfam (NCBI)pfam01510   
Domain families : Smart (EMBL)Ami_2 (SM00644)  PGRP (SM00701)  
Conserved Domain (NCBI)PGLYRP2
DMDM Disease mutations114770
Blocks (Seattle)PGLYRP2
SuperfamilyQ96PD5
Human Protein AtlasENSG00000161031
Peptide AtlasQ96PD5
HPRD10495
IPIIPI00163207   IPI00394992   
Protein Interaction databases
DIP (DOE-UCLA)Q96PD5
IntAct (EBI)Q96PD5
FunCoupENSG00000161031
BioGRIDPGLYRP2
STRING (EMBL)PGLYRP2
ZODIACPGLYRP2
Ontologies - Pathways
QuickGOQ96PD5
Ontology : AmiGOpeptide amidation  pattern recognition receptor signaling pathway  extracellular region  intracellular  zinc ion binding  N-acetylmuramoyl-L-alanine amidase activity  N-acetylmuramoyl-L-alanine amidase activity  peptidoglycan catabolic process  peptidoglycan receptor activity  membrane  detection of bacterium  antimicrobial humoral response  negative regulation of interferon-gamma production  negative regulation of natural killer cell differentiation involved in immune response  peptidoglycan binding  growth of symbiont in host  innate immune response  regulation of inflammatory response  defense response to Gram-positive bacterium  extracellular exosome  
Ontology : EGO-EBIpeptide amidation  pattern recognition receptor signaling pathway  extracellular region  intracellular  zinc ion binding  N-acetylmuramoyl-L-alanine amidase activity  N-acetylmuramoyl-L-alanine amidase activity  peptidoglycan catabolic process  peptidoglycan receptor activity  membrane  detection of bacterium  antimicrobial humoral response  negative regulation of interferon-gamma production  negative regulation of natural killer cell differentiation involved in immune response  peptidoglycan binding  growth of symbiont in host  innate immune response  regulation of inflammatory response  defense response to Gram-positive bacterium  extracellular exosome  
NDEx NetworkPGLYRP2
Atlas of Cancer Signalling NetworkPGLYRP2
Wikipedia pathwaysPGLYRP2
Orthology - Evolution
OrthoDB114770
GeneTree (enSembl)ENSG00000161031
Phylogenetic Trees/Animal Genes : TreeFamPGLYRP2
HOVERGENQ96PD5
HOGENOMQ96PD5
Homologs : HomoloGenePGLYRP2
Homology/Alignments : Family Browser (UCSC)PGLYRP2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPGLYRP2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PGLYRP2
dbVarPGLYRP2
ClinVarPGLYRP2
1000_GenomesPGLYRP2 
Exome Variant ServerPGLYRP2
ExAC (Exome Aggregation Consortium)PGLYRP2 (select the gene name)
Genetic variants : HAPMAP114770
Genomic Variants (DGV)PGLYRP2 [DGVbeta]
DECIPHERPGLYRP2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPGLYRP2 
Mutations
ICGC Data PortalPGLYRP2 
TCGA Data PortalPGLYRP2 
Broad Tumor PortalPGLYRP2
OASIS PortalPGLYRP2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPGLYRP2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPGLYRP2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PGLYRP2
DgiDB (Drug Gene Interaction Database)PGLYRP2
DoCM (Curated mutations)PGLYRP2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PGLYRP2 (select a term)
intoGenPGLYRP2
Cancer3DPGLYRP2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608199   
Orphanet
MedgenPGLYRP2
Genetic Testing Registry PGLYRP2
NextProtQ96PD5 [Medical]
TSGene114770
GENETestsPGLYRP2
Target ValidationPGLYRP2
Huge Navigator PGLYRP2 [HugePedia]
snp3D : Map Gene to Disease114770
BioCentury BCIQPGLYRP2
ClinGenPGLYRP2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD114770
Chemical/Pharm GKB GenePA134929965
Clinical trialPGLYRP2
Miscellaneous
canSAR (ICR)PGLYRP2 (select the gene name)
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePGLYRP2
EVEXPGLYRP2
GoPubMedPGLYRP2
iHOPPGLYRP2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Tue Aug 1 16:35:47 CEST 2017

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