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PGLYRP3 (peptidoglycan recognition protein 3)

Identity

Alias_symbol (synonym)PGRPIA
PGLYRPIalpha
PGRP-Ialpha
Other alias
HGNC (Hugo) PGLYRP3
LocusID (NCBI) 114771
Atlas_Id 71865
Location 1q21.3  [Link to chromosome band 1q21]
Location_base_pair Starts at 153297862 and ends at 153310718 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PGLYRP3   30014
Cards
Entrez_Gene (NCBI)PGLYRP3  114771  peptidoglycan recognition protein 3
AliasesPGLYRPIalpha; PGRP-Ialpha; PGRPIA
GeneCards (Weizmann)PGLYRP3
Ensembl hg19 (Hinxton)ENSG00000159527 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000159527 [Gene_View]  chr1:153297862-153310718 [Contig_View]  PGLYRP3 [Vega]
ICGC DataPortalENSG00000159527
TCGA cBioPortalPGLYRP3
AceView (NCBI)PGLYRP3
Genatlas (Paris)PGLYRP3
WikiGenes114771
SOURCE (Princeton)PGLYRP3
Genetics Home Reference (NIH)PGLYRP3
Genomic and cartography
GoldenPath hg38 (UCSC)PGLYRP3  -     chr1:153297862-153310718 -  1q21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PGLYRP3  -     1q21.3   [Description]    (hg19-Feb_2009)
EnsemblPGLYRP3 - 1q21.3 [CytoView hg19]  PGLYRP3 - 1q21.3 [CytoView hg38]
Mapping of homologs : NCBIPGLYRP3 [Mapview hg19]  PGLYRP3 [Mapview hg38]
OMIM608197   
Gene and transcription
Genbank (Entrez)AY035376 BC069741 BC069798 BC069801 BC128114
RefSeq transcript (Entrez)NM_052891
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PGLYRP3
Cluster EST : UnigeneHs.348266 [ NCBI ]
CGAP (NCI)Hs.348266
Alternative Splicing GalleryENSG00000159527
Gene ExpressionPGLYRP3 [ NCBI-GEO ]   PGLYRP3 [ EBI - ARRAY_EXPRESS ]   PGLYRP3 [ SEEK ]   PGLYRP3 [ MEM ]
Gene Expression Viewer (FireBrowse)PGLYRP3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)114771
GTEX Portal (Tissue expression)PGLYRP3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96LB9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96LB9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96LB9
Splice isoforms : SwissVarQ96LB9
PhosPhoSitePlusQ96LB9
Domains : Interpro (EBI)Amidase_domain    PGRP    PGRP_domain_met/bac   
Domain families : Pfam (Sanger)Amidase_2 (PF01510)   
Domain families : Pfam (NCBI)pfam01510   
Domain families : Smart (EMBL)Ami_2 (SM00644)  PGRP (SM00701)  
Conserved Domain (NCBI)PGLYRP3
DMDM Disease mutations114771
Blocks (Seattle)PGLYRP3
PDB (SRS)1SK3    1SK4    1TWQ    2APH   
PDB (PDBSum)1SK3    1SK4    1TWQ    2APH   
PDB (IMB)1SK3    1SK4    1TWQ    2APH   
PDB (RSDB)1SK3    1SK4    1TWQ    2APH   
Structural Biology KnowledgeBase1SK3    1SK4    1TWQ    2APH   
SCOP (Structural Classification of Proteins)1SK3    1SK4    1TWQ    2APH   
CATH (Classification of proteins structures)1SK3    1SK4    1TWQ    2APH   
SuperfamilyQ96LB9
Human Protein AtlasENSG00000159527
Peptide AtlasQ96LB9
HPRD16297
IPIIPI00064969   
Protein Interaction databases
DIP (DOE-UCLA)Q96LB9
IntAct (EBI)Q96LB9
FunCoupENSG00000159527
BioGRIDPGLYRP3
STRING (EMBL)PGLYRP3
ZODIACPGLYRP3
Ontologies - Pathways
QuickGOQ96LB9
Ontology : AmiGOpattern recognition receptor signaling pathway  extracellular region  intracellular  zinc ion binding  N-acetylmuramoyl-L-alanine amidase activity  peptidoglycan catabolic process  peptidoglycan receptor activity  membrane  detection of bacterium  antimicrobial humoral response  negative regulation of interferon-gamma production  negative regulation of natural killer cell differentiation involved in immune response  peptidoglycan binding  growth of symbiont in host  innate immune response  defense response to Gram-positive bacterium  
Ontology : EGO-EBIpattern recognition receptor signaling pathway  extracellular region  intracellular  zinc ion binding  N-acetylmuramoyl-L-alanine amidase activity  peptidoglycan catabolic process  peptidoglycan receptor activity  membrane  detection of bacterium  antimicrobial humoral response  negative regulation of interferon-gamma production  negative regulation of natural killer cell differentiation involved in immune response  peptidoglycan binding  growth of symbiont in host  innate immune response  defense response to Gram-positive bacterium  
NDEx NetworkPGLYRP3
Atlas of Cancer Signalling NetworkPGLYRP3
Wikipedia pathwaysPGLYRP3
Orthology - Evolution
OrthoDB114771
GeneTree (enSembl)ENSG00000159527
Phylogenetic Trees/Animal Genes : TreeFamPGLYRP3
HOVERGENQ96LB9
HOGENOMQ96LB9
Homologs : HomoloGenePGLYRP3
Homology/Alignments : Family Browser (UCSC)PGLYRP3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPGLYRP3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PGLYRP3
dbVarPGLYRP3
ClinVarPGLYRP3
1000_GenomesPGLYRP3 
Exome Variant ServerPGLYRP3
ExAC (Exome Aggregation Consortium)PGLYRP3 (select the gene name)
Genetic variants : HAPMAP114771
Genomic Variants (DGV)PGLYRP3 [DGVbeta]
DECIPHERPGLYRP3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPGLYRP3 
Mutations
ICGC Data PortalPGLYRP3 
TCGA Data PortalPGLYRP3 
Broad Tumor PortalPGLYRP3
OASIS PortalPGLYRP3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPGLYRP3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPGLYRP3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PGLYRP3
DgiDB (Drug Gene Interaction Database)PGLYRP3
DoCM (Curated mutations)PGLYRP3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PGLYRP3 (select a term)
intoGenPGLYRP3
Cancer3DPGLYRP3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608197   
Orphanet
MedgenPGLYRP3
Genetic Testing Registry PGLYRP3
NextProtQ96LB9 [Medical]
TSGene114771
GENETestsPGLYRP3
Target ValidationPGLYRP3
Huge Navigator PGLYRP3 [HugePedia]
snp3D : Map Gene to Disease114771
BioCentury BCIQPGLYRP3
ClinGenPGLYRP3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD114771
Chemical/Pharm GKB GenePA134861692
Clinical trialPGLYRP3
Miscellaneous
canSAR (ICR)PGLYRP3 (select the gene name)
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePGLYRP3
EVEXPGLYRP3
GoPubMedPGLYRP3
iHOPPGLYRP3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:34:25 CEST 2017

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